HeBei Med

Home | About Us | Editorial Board | Instruction | Subscribe | Advertisement | Messages | Contact Us | 中文

Office Online

Journal

Advanced Search

Download

Links

2017 Vol. 23, No. 12 Published: 2017-12-30

	1937	Cytogenetic Analysis of 1032 Male Infertility Patients
		CHAI Beibei, HE Pei, WANG Huiying, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.001
		Objective: To investigate the detection rate and abnormal type of abnormal chromosome karyotype in infertile patients. Methods: 1032 infertile patients' peripheral blood lymphocytes were detected by G banding karyotype analysis. Results: 51 cases of chromosomal abnormalities were found in 1032 male patients, the detection rate was 4.94%. Among them, there are 3 cases of sex chromosomal abnormalities, 11 cases of autosmal abnormalities, 37 cases of chromosome polymorphism changed, the 37 cases state including 8 cases of sex chromosomal polymorphism changed and 29 cases of autosomal polymorphic changed. Most clinical manifestations are weak symptoms, azoospermia and spouse repeated abortion. Conclusion: In male infertility patients, not only need to carry out routine analysis of semen, but also carry their abnormal chromosomes or chromosome polymorphisms detected to prevent patients from transmitting these abnormal chromosomes to the next generation, resulting in its offspring of infertility.
		2017 Vol. 23 (12): 1937-1939 [Abstract] ( 1154 ) HTML (1 KB) PDF (1372 KB) ( 647 )

	1940	Three Dimensional Ultrasound Dynamic of Anatomical Function Remodeling of Levator ani muscle Hiatus in late Pregnant Women with Constipation
		MU Liang, LIU Li, WEI Aihua, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.002
		Objective: To observe the morphological characteristics of pelvic diaphragm hiatus in late-pregnant women with constipation by transperineal three-dimensional ultrasonography. Methods: Primiparous singleton selected from July 2014 to June 2017 in our hospital for regular prenatal examination in late pregnancy, 140 cases of full-term pregnancy (pregnancy group), including 48 cases of constipation symptoms (constipation pregnant women), 92 cases without symptoms of constipation (constipation; non pregnant women) were selected without constipation nonparous health 100 women (control group). The size of levator ani muscle and the thickness of pubic rectal muscle were measured in 3 states: resting state, anal sphincter movement and Valsalva maneuver. Results: Loosen connective tissue was observed in some pregnant women in the late pregnancy group.The perimeter and area of pelvic diaphragm hiatus and pubovisceral muscle thickness were significantly increased than those in control group, at rest, on maximum pelvic floor contraction and maximum Valsalva respectively (P＜0.05).And the perimeter and area of pelvic diaphragm hiatus in pregnant women with constipation were increased than those without constipation at three maneuvers,respectively(P＜0.05).Pubovisceral muscle thickness in pregnant women with constipation was significantly thinner than those in pregnant women without constipation at maximum pelvic floor contraction(P＜0.05), but there was no significant difference between pregnant women with constipation and without constipation at rest and on maximum Valsalva in pubovisceral muscle thickness (P＞0.05).Conclusion: Pelvic floor anatomic remodeling is identified in late pregnant women.Transperineal three-dimensional ultrasonography has great value for　pelvic floor change in late pregnant women,especially pregnancy with constipation .
		2017 Vol. 23 (12): 1940-1943 [Abstract] ( 768 ) HTML (1 KB) PDF (1411 KB) ( 416 )

	1944	The Prognostic Value of HPV16-E6-DNA for Cervical Cancer
		CHENG Yingxing, HUANG Yong
		DOI: 10.3969/j.issn.1006-6233.2017.12.003
		Objective: To explore the prognostic value of HPV16-E6-DNA in cervical cancer. Methods: A retrospective analysis of our hospital in January 2014 ~2017 year in March 72 cases of cervical cancer patients with clinical data, blood tests, using fluorescence quantitative (PCR) technique for detection of HPV16-E6-DNA virus load, according to the test results of the patients were divided into two groups, namely low load and high load group, using fluorescence quantitative (RT-PCR) determination of cervix cancer tissue HPV16-E6-DNA viral load, using Kaplan-Meier to calculate the survival rates of the two groups, using the factor Cox regression analysis in patients with 5-year-survival rates. Results: The expression levels of HPV16-E6-DNA viral load in patients with cervical cancer were related to age, FIGO stage and lymph node metastasis (P<0.05); The 1, 3 and 5 year survival rates of the patients in the low load group were 95.66%, 89.31% and 74.30% respectively; The 1, 3 and 5 year survival rates of the patients in the high load group were 89.10%, 62.61% and 51.36% respectively; The survival rate of patients in the low load group was significantly higher than that of high load group, the difference was statistically significant (P<0.05); Cox regression analysis showed that HPV16-E6-DNA viral load and lymph node metastasis were the important factors affecting the prognosis of patients with cervical cancer (P<0.05). Conclusion: HPV16-E6-DNA virus is an important predictor of the prognosis of cervical cancer patients. It is an important factor in the prognosis of cervical cancer after radical resection. It is also an independent factor in the survival rate of cervical cancer after radical operation.
		2017 Vol. 23 (12): 1944-1947 [Abstract] ( 676 ) HTML (1 KB) PDF (1402 KB) ( 377 )

	1948	Distribution and Preventive Measures of Nosocomial Infection of Acinetobacter Bauman in Hospital
		HUANG Qun, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.004
		Objective: To analyze the distribution characteristics and drug resistance of pathogens causing nosocomial infection in hospitalized patients, and to explore the prevention and control measures of nosocomial infection. Methods: 648 cases of nosocomial infection were collected in our hospital during the past 6 years, and the positive strains were selected. The sources, bacterial spectrum and drug resistance of the specimens were analyzed. Results: The incidence of lower respiratory tract infection and wound infection in hospitalized patients was higher, and there was significant difference compared with other sites (P<0.01); The infection of Bauman and Staphylococcus aureus was more common, and compared with other bacteria species, there were significant differences (P<0.01, P<0.05); The infection of Acinetobacter baumannii was sensitive to imipenem and Cefoperazone / sulbactam, but the drug resistance rate was on the rise with the duration of administration of Bauman. Conclusion: Bauman Acinetobacter infection rate is higher in hospitalized patients. With the extension of the drug and the increase in the types of drugs, The rate of drug resistance is more and more high. In order to prevent and correct diagnose and treat, positive measures should be take.
		2017 Vol. 23 (12): 1948-1951 [Abstract] ( 611 ) HTML (1 KB) PDF (1398 KB) ( 411 )

	1952	The Effect of Eustachian Tube Balloon Dilatation in Children with Secretory Otitis Media
		BU Yang, JIN Xin
		DOI: 10.3969/j.issn.1006-6233.2017.12.005
		Objective: To analyze the effect of eustachian tube balloon dilatation in children with secretory otitis media. Methods: 76 children with secretory otitis media admitted in our hospital from July 2015 to July 2016 were selected as objects. According to the order of admission, the patients were divided into observation group and control group. The control group received conservative treatment, the observation group using eustachian tube balloon dilatation. (ETA), tympanic membrane healing time, normal hearing time, duration of disappearance of tinnitus and nausea, and duration of effusion were compared between the two groups. Results: After treatment, the total effective rate of the observation group was significantly higher than that of the control group [89.47% (34/38) vs 65.79% (25/38)] (P <0.05). The PTA of the observation group was significantly lower than that of the control group [(20.04 ± 2.31) dB VS(25.38 ± 2.87) dB](P <0.05), and the ETS value was significantly higher than that of the control group[(20.14±2.31)points VS (13.27±1.26)points] (P <0.05). In the observation group, tympanic membrane healing, hearing recovery, the time of disappearance of tinnitus and the duration of effusion were shorter than those in the control group (P <0.05). Conclusion: Eustachian tube balloon dilatation is used in children with secretory otitis media, which the clinical curative effect is good.
		2017 Vol. 23 (12): 1952-1955 [Abstract] ( 507 ) HTML (1 KB) PDF (1389 KB) ( 289 )

	1956	Effect of Bronchoscopic Balloon Dilatation combined with Local Injection of Tramcinolone Acetonide in the Treatment of Tuberculous Bronchial Stenosis
		CAI Xiangjing, HOU Yulian, DUAN Yueting
		DOI: 10.3969/j.issn.1006-6233.2017.12.006
		Objective: To analyze the effect of bronchoscopic balloon dilatation combined with local injection of tramcinolone acetonide in the treatment of tuberculous bronchial stenosis. Methods: 120 cases of tuberculous bronchial stenosis treated in our hospital from January, 2013 to March 2016 were selected. The patients in the conventional group were treated with bronchial balloon dilatation, and the experimental group was treated with bronchoscopic balloon dilatation combined with triamcinolone acetonide injection. Results: Treatment of the experimental group and the conventional group total effective rate were 95% and 81.67%, P < 0.05; the experimental group after treatment FEV1 score and shortness of breath were significantly better than the conventional group, P < 0.05. Conclusion: The effect of balloon high pressure dilation combined with triamcinolone acetonide on tuberculous bronchial stenosis is remarkable.
		2017 Vol. 23 (12): 1956-1957 [Abstract] ( 507 ) HTML (1 KB) PDF (1367 KB) ( 258 )

	1958	Clinical Analysis of Percutaneous Transforaminal Endoscopic Discectomy Combined with Rehabilitation in the Treatment of Lumbar Disc Herniation
		LV Xuefeng, BAI Xiaojie, CAO Biying
		DOI: 10.3969/j.issn.1006-6233.2017.12.007
		Objective: To investigate the clinical efficacy and related factors of percutaneous transforaminal lumbar discectomy (PTED) combined with rehabilitation training in the treatment of lumbar disc herniation (LDH). Methods: 50 patients with LDH admitted to our hospital from October 2014 to October 2016 were treated with PTED and perioperative period to 6 months postoperative rehabilitation. The VAS score, SAS score, ODI index and SF-36 score were observed and compared before and after the operation. Serum levels of IL-1β, MMP-3 and TNF-α were measured and compared before and after operation; Univariate analysis was used to analyze the clinical parameters affecting the therapeutic effect. Results: After treatment, 12 cases were excellent, good in 18 cases, fair in 17 cases and poor in 3 cases, the total effective rate was 94.00%. Compared with preoperative, VAS, SAS score and ODI index increased 1 d after operation, and the SF-36 score decreased (P<0.05 or P<0.01); the SAS, VAS score and ODI index showed a decreasing trend from 1 months to 6 months after operation and the SF-36 score showed an increasing trend (P<0.05 or P<0.01). Compared with the preoperative, serum IL-1β, MMP-3 and TNF-α levels were significantly lower (P<0.01). Excellent and good patients were classified as good prognosis group (n=30), fair and poor patients were classified as poor prognosis group (n=20), there was a significant correlation between the age and the course of disease and the clinical curative effect (P<0.05). Conclusion: PTED combined with rehabilitation training can significantly reduce the postoperative pain, relieve anxiety, promote the recovery of lumbar function, inhibit the inflammatory response and improve the quality of life of patients. At the same time, the patient's age, course of disease can affect the clinical treatment effect.
		2017 Vol. 23 (12): 1958-1962 [Abstract] ( 491 ) HTML (1 KB) PDF (1407 KB) ( 276 )

	1963	Effects of Alprostadil Combined with Telbivudine on Clinical Efficacy and Serum Inflammatory Factor in Patients of Hepatitis B Virus-related Cirrhosis
		CHEN Xun, LIU Haibin
		DOI: 10.3969/j.issn.1006-6233.2017.12.008
		Objective: To explore clinical efficacy and serum inflammatory factor use of alprostadil combined with telbivudine in treatment of hepatitis B virus-related cirrhosis,providing a theoretical basis for clinical treatment. Methods:98 patients with hepatitis B cirrhosis admitted in our hospital from June 2014 to June 2016, were selected. According to the random number table, patients were divided into telbivudine group (49 cases) and combined group (49 cases). On the basis of routine treatment, telbivudine group was given telbivudine, combined group was given telbivudine and alprostadil for 12 weeks. To observe and analyze the changes of serum HBV DNA levels, liver function and serum inflammatory factor. Results:After treatment, overall efficacy of combined group was significantly higher than that of telbivudine group (89.30% VS.63.89%,P< 0.05).After treatment, the serum HBV and DNA levels of the two groups were significant lower than those before treatment,but there was no significant difference (P>0.05) between two groups. After treatment, serum AST, ALT, Tbil, IL-6, IL-22 and hs-CRP levels of combined group were significantly lower than those of telbivudine group (P<0.05). Conclusion:Alprostadil combined with telbivudine could reduce serum HBV DNA levels, improve liver function, and alleviate the inflammatory condition of patients with ghepatitis B virus-related cirrhosis.
		2017 Vol. 23 (12): 1963-1965 [Abstract] ( 479 ) HTML (1 KB) PDF (1385 KB) ( 386 )

	1966	Comparing the Effects of Cemented Artificial Hip Hemiarthroplasty and Total Hip Replacement on ESR, CRP and SAA Levels in Elderly Patients with Severe Hip Disease
		LEI Yunfeng, GAO Shansong, GAO Zhi
		DOI: 10.3969/j.issn.1006-6233.2017.12.009
		Objective: To compare the effects of total hip arthroplasty and hemiarthroplasty on serum erythrocyte sedimentation rate (ESR), C reactive protein (CRP) and amyloid A (SAA) levels in elderly patients with severe hip disease. Methods: 124 elderly patients with severe hip disease who underwent artificial hip replacement in our hospital from January 2013 to June 2016 were selected. Among them, 56 patients received bone cement artificial hip replacement and 68 cases were treated with bone cement artificial total hip arthroplasty. Then surgical related indicators, hip Harris score, the changes of serum ESR, CRP and SAA levels of the two groups before and after the treatment were compared. Results: Replacement time, intraoperative blood loss, postoperative drainage volume, postoperative activity time and hospitalization time of the hemiarthroplasty group were significantly lower than that of the total hip replacement group (P<0.01), there was no significant difference in complication rate between the two groups (P>0.05); the levels of serum ESR, CRP and SAA of 1, 3, 7 and 14d of the hemiarthroplasty group were significantly lower than those of the total hip replacement group of the same time period (P<0.05); There was no significant difference in hip Harris score between the two groups before and 3 months after the surgery (P>0.05). Conclusion: The effect of bone cement type artificial hip joint replacement cementless hemiarthroplasty is similar to the bone cement type artificial hip replacement in the treatment of elderly patients with severe hip joint diseases. But cemented hip replacement has lighter inflammation, less surgical trauma, with better patients'tolerablity, so it is more suitable for elderly patients with poor general condition.
		2017 Vol. 23 (12): 1966-1969 [Abstract] ( 391 ) HTML (1 KB) PDF (1408 KB) ( 281 )

	1970	Clinical Analysis of Granulocyte Colony-stimulating Factor in the Treatment of Ischemic Stroke
		LI Yuyang, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.010
		Objective: To investigate the value of granulocyte colony-stimulating factor (G-CSF) in the treatment of patients with ischemic stroke and the effect on neurological function. Methods: A total of 120 patients with ischemic stroke were selected as study subjects. By the random number table method, they were divided into study group and control group, 60 cases in each group. The control group (60 cases, 56 cases completed, 4 cases lost to follow up) was treated with conventional symptomatic treatment (thrombolysis, anticoagulation, improving cerebral circulation, lowering intracranial pressure, oxygen inhalation, anti-infection, oxygen inhalation, anti-encephaledema, cerebral protection, etc.); the study group (60 cases, 54 cases completed, 6 cases lost to follow up), was treated combined with recombinant human G-CSF injection [2μg/(kg·d), iH, for 5d], based on the treatment in the control group; curative effect in both groups was observed after 12 weeks of treatment. Changes of serum neuron specific enolase (NSE), neuropeptide Y (NPY), serum nuclear factor kappa B (NF-κB) and inflammatory factors [interleukin - 6 (IL-6), tumor necrosis factor alpha (TNF-α)] before and after treatment were compared between the two groups. The incidence of adverse reactions was recorded, and the differences in neurological function recovery before and after treatment were analyzed. Results: After 5d and 12 weeks of treatment, the test results of serum NSE, NPY, NF-κB, serum IL-6, TNF-a and other inflammatory cytokines and NFDS scores in both groups were significantly lower than those before treatment, and the study group was lower than the control group (P < 0.05). There were no serious adverse reactions in both groups, and there were no significant differences in the incidence rates of mild anorexia, nausea, muscular soreness, rash and other adverse reactions between the two groups (P > 0.05). Conclusion: G-CSF can effectively promote the recovery of neurological function in patients with ischemic stroke, and the anti-inflammation effect is ideal, which is beneficial to the prognosis of patients.
		2017 Vol. 23 (12): 1970-1973 [Abstract] ( 324 ) HTML (1 KB) PDF (1398 KB) ( 350 )

	1974	Clinical Observation on Letrozole Combined with Low Dose and High Purity Gonadotropin Efficacy in Treatment of Polycystic Ovary Syndrome with CC Nike Anovulatory Infertility Patients
		SHI Ying
		DOI: 10.3969/j.issn.1006-6233.2017.12.011
		Objective: To investigate letrozole (LTZ) combined with low dose of high purity gonadotropin (Hp-HMG) in treatment of polycystic ovary syndrome with CC Nike anovulatory infertility. Methods: 160 cases of PCOS patients admitted in gynecological clinics of our hospital from July 2014 to June 2016 were selected as the research object, randomly divided into experimental group and control group. Two groups of patients in the early stage of treatment were the same, the late ovulation treatment was different. The experimental group was treated with LTZ combined with Hp-HMG, and the control group was treated with Hp-HMG alone. All the patients were treated for 2 weeks. The indexes related to ovulation, follicular development and endometrial thickness were statistically evaluated, and the clinical pregnancy rates of the two groups were compared. Results: The ovulation rate and the rate of ovulation of the single follicle in the experimental group were significantly different from those in the control group(χ²=4.195,8.789,P<0.05),the average treatment cycle was significantly shorter than that of the control group(t=6.665,P<0.05);the number of mature follicles, the diameter of the largest follicles and the thickness of endometrium in the experimental group were significantly higher than those in the control group(t=23.605,8.556,18.742,P<0.05);The clinical pregnancy rate of the experimental group (48.7%) was significantly higher than that of the control group (20%), the difference was statistically significant (P<0.05). Conclusion: Letrozole (LTZ) combined with low dose of high purity urinary stimulating hormone (Hp-HMG) treatment of PCOS is better than Hp-HMG alone, which is more conducive to the development of follicular maturation, help endometrial growth, improve the clinical pregnancy rate.
		2017 Vol. 23 (12): 1974-1977 [Abstract] ( 245 ) HTML (1 KB) PDF (1410 KB) ( 259 )

	1978	Experience of Drip Bipolar Coagulation in Thyroid Surgery
		CHEN Yong, ZHANG Liuyang, XUE Junxing, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.012
		Objective: To explore the effect of drip bipolar coagulation in thyroid surgery. Method: 520 patients underwent thyroid operation were divided into research group and control group. Patients in the research group were treated by drip bipolar coagulation and patients in the control group were treated by harmonic scalpel in thyroidectomy. The operative time, bleeding, palsy of recurrent laryngeal nerve, total lead flow after operation, postoperative PTH and the blood calcium were compared between the two groups. Result: There was no difference of the operative time and bleeding in the two groups (P >0.05), but the total lead flow after operation were statistical difference (P<0.05). The complications of transient palsy of recurrent laryngeal nerve and transient function insufficiency of parathyroid were more in the control group (8.4% and 9.2%) than in the research group (4.2% and 5.0%) with statistical difference (P<0.05). There were no permanent palsy of recurrent laryngeal nerve and permanent function insufficiency of parathyroid in the two groups. Conclusion: Drip bipolar coagulation for thyroid operation is safe and can effectively reduce the surrounding temperature of the important tissue, and can protect the recurrent laryngeal nerve and parathyroid and shorten the time of drain in the wound.
		2017 Vol. 23 (12): 1978-1980 [Abstract] ( 583 ) HTML (1 KB) PDF (1391 KB) ( 444 )

	1981	Clinical Efficacy and its Quality of Life of Aidi Injection Combined with Taxol and Platinum-based Drug in the Treatment of Elderly Patients with Middle-late Stage Non-small Cell Lung Cancer
		LIU Taifeng, CHEN Xiangmei, QIN Xiaobing
		DOI: 10.3969/j.issn.1006-6233.2017.12.013
		Objective: To evaluate the clinical effect and its influence on the quality of life of Aidi injection combined with chemotherapy of taxol and Platinum-based drug in the treatment of elderly patients with middle-late stage non-small cell lung cancer. Methods: 60 patients with advanced non-small cell lung cancer patients were randomly divided into observation group and control group, the control group in first, 8 days with paclitaxel, given cis-platinum complexes on the first day, the observation group were given intravenous injection Addie on the basis of the control group. With 1 cycles per 21 d, each patient completed at least 2 cycles of chemotherapy. The clinical efficacy of two groups and their influence on the quality of life of patients were observed and compared. Results: Comparison of the clinical efficacy of the two groups after treatment, the difference was not statistically significant (Z=-1.202, P>0.05), but the effective rate of the observation group was higher than that of the control group. The observation group patients to improve the quality of life was significantly higher than that of control group, the difference was statistically significant (χ²=4.022, P<0.05). There was no significant difference between the observation group and the control group in allergic reaction, alopecia and neurotoxicity (P>0.05), but there was significant difference between the two groups in incidence of adverse reactions of digestive tract (χ² = 1.663, P <0.05). Conclusion: Aidi injection combined with chemotherapy of taxol and Platinum-based drug in the treatment,it can alleviate the clinical symptoms of elderly patients with advanced non-small cell lung cancer, improve the quality of life, and alleviate the adverse drug reactions caused by chemotherapy.
		2017 Vol. 23 (12): 1981-1983 [Abstract] ( 440 ) HTML (1 KB) PDF (1390 KB) ( 307 )

	1984	Clinical Analysis of Temporary Pacemaker treated with Acute Myocardial Infarction complicated with Slow Arrhythmia
		NIU Hongmei
		DOI: 10.3969/j.issn.1006-6233.2017.12.014
		Objective: To investigate the clinical efficacy of temporary pacemaker in the treatment of acute myocardial infarction with slow arrhythmia. Methods: 100 cases of acute myocardial infarction with slow arrhythmia patients admitted to our hospital in March 2010 to March 2017 selected in random number table method were divided into two groups. Patients in the control group were given drug therapy + interventional therapy, and patients in the experimental group were treated with temporary pacemakers. The disease related parameters, myocardial perfusion classification, cardiac function, reperfusion injury, follow-up cardiovascular events and quality of life were compared between the two groups. Results: Compared with the control group, the systolic blood pressure, diastolic blood pressure and left ventricular ejection fraction were significantly higher in the experimental group than those in the control group. The left ventricular end diastolic diameter, left ventricular systolic diameter, BNP, CK-MB and cTnT (P <0.05) . There was significant difference between the TIMI grade and the NYHA grade in the control group. The incidence of cardiovascular events was significantly lower than that of the control group. The quality of life scores were significantly higher than those of the control group at 6 months after treatment (P <0.01). The incidence of total reperfusion injury was significantly higher than that of the control group (P <0.05). Conclusion: The clinical efficacy of temporary pacemaker treatment with acute myocardial infarction complicated with slow arrhythmia is significant and has reference significance.
		2017 Vol. 23 (12): 1984-1987 [Abstract] ( 394 ) HTML (1 KB) PDF (1399 KB) ( 209 )

	1988	Effect of Low Dose Methylprednisolone and High Effective Dose of Dexamethasone Decreased with Sudden Sensorineural Hearing Loss in the whole Frequency Therapeutic Effect
		WANG Qinghai, XIONG Xiangjing, LI Junjuan
		DOI: 10.3969/j.issn.1006-6233.2017.12.015
		Objective: To study and compare the treatment effect of low equivalent dose of methylprednisolone and high dose equivalent of dexamethasone for full frequency descent type of sudden deafness. Methods: From January 2014 to December 2016, 100 cases of patients with full frequency decline of sudden sensorineural hearing loss were selected as the research object, and they were randomly divided into two groups by taking computer random number method, each group had 50 cases, A group was treated with methylprednisolone, B group was treated with dexamethasone, after 2 weeks of treatment, the clinical curative effect, full frequency pure tone average and the incidence of adverse reaction were compared between two groups. Results: The total effective rate in A group and B group were 88%, 84%, the difference was not statistically significant (P>0.05); after treatment, the full frequency pure tone average in two groups were significantly improved (P<0.05), and the full frequency pure tone average in two groups was compared, there was no statistically significant difference (P>0.05); the adverse reactions in A group and B group were respectively 6%, 4%, the difference was not statistically significant (P>0.05). Conclusion: The low dose methylprednisolone and high effective dose of dexamethasone in the treatment for full frequency descent type of sudden deafness both have significant curative effect, can effectively improve the hearing of the patients, and the safety of the two medicine are very reliable.
		2017 Vol. 23 (12): 1988-1990 [Abstract] ( 274 ) HTML (1 KB) PDF (1393 KB) ( 226 )

	1991	The Safety and Clinical Efficacy of Etonogestrel-releasing Implant in the Treatment of Adenomy
		HUA Hua, CAO Xixia, ZHU Hui
		DOI: 10.3969/j.issn.1006-6233.2017.12.016
		Objective: To evaluate the efficacy and safety of a etonogestrel-releasing implant in treatment of adenomyosis. Methods: 30 cases of adenomyosis patients admitted in our hospital from January 2015 to January 2017 were selected as the research object, adopt treatment etonogestrel implants, respectively, on the fifth day after operation, first, 3, 6, and 12 months postoperatively. The analysis of the contraceptive effect, relieve dysmenorrhea degree, after months of treatment and the curative effect of adverse reactions the degree of dysmenorrhea; using visual analog scale (VAS) assessment. Results: The contraceptive rate is as high as 100%.30 cases of adenomyosis patients had different degrees of dysmenorrhea before subcutaneous implantation, and the degree of dysmenorrhea was relieved or disappeared 3 months after implantation (P＜0.05). There were 12 cases of menorrhagia, menostaxis patients treated for 1 months, 3 months, 6 months, 12 months after the endometrial thickness compared with before treatment were significantly thinner (P<0.05),the volume of uterus treated for 1 months and 3 months later was not different from that before treatment(P>0.05; treatment for 6 months and 12 months was significantly lower than before treatment(P<0.05). The major adverse effect during the follow-up period was a change in bleeding patterns. Conclusion: The treatment of adenomyosis with subcutaneous implants can effectively relieve dysmenorrhea, and can treat menorrhagia. It is safe and reliable and can be popularized in clinical practice.
		2017 Vol. 23 (12): 1991-1993 [Abstract] ( 262 ) HTML (1 KB) PDF (1392 KB) ( 492 )

	1994	The Research on Clinical Curative Effect and Safety of Bozhi Glycopeptide Injection in the Treatment of Large Areas of Psoriasis Vulgaris
		WANG Yingquan
		DOI: 10.3969/j.issn.1006-6233.2017.12.017
		Objective: To evaluate the clinical curative effect and safety of Bozhi Glycopeptide Injection in the treatment of large areas of psoriasis vulgaris. Methods: One hundred and six cases of patients with large areas of psoriasis vulgaris were randomly divided into the control group and treatment group, 53 cases in each group. The control group was given A citretin capsule 30mg, qd, orally, on the basis of the control group, the experimental group was treated with Shen Qi Bozhi Glycopeptide Injection 4ml, qd, intravenous drip. Before and after treatment, compared between the two groups of patients with serum tumor necrosis factorα (TNF- α), interleukin 6(IL-6) , interleukin 17A(IL-17A) levels, interleukin-22(IL-22), interferonγ(INF-γ) , vascular endothelial growth factor (VEGF) , soluble E selectin (sE-slelctin) , soluble intercellular adhesion molecule -1 (sICAM-1) , efficiency of treatment and incidence of adverse reactions. Results: After treatment, serum levels of TNF-α, IL-6, IL-17A, IL-22, INF-γ,VEGF, sE-slelctin, sICAM-1 in the control group respectively were(91.65±12.87) pg/mL,(89.76±11.08)pg/mL,(16.46±1.55)pg/mL,(45.23±6.11)pg/mL,(16.52±2.47)pg/mL,(152.34±20.08)pg/mL,(43.29±5.78)ng/mL,(117.21±10.29)μg/L,, the levels of the above indicators in the experimental group respectively were (49.57±7.02) pg/mL, (58.46±7.66)pg/mL,(10.75±1.23)pg/mL,(38.23±5.01)pg/mL,(9.75±1.32)pg/mL,(123.12±12.54)pg/mL,(29.55±4.21)ng/mL,(98.75±12.13)μg/L, compared with the control group, the serum levels of TNF-α, IL-6, IL-17A, IL-22, INF-γ, VEGF, sE-slelctin, sICAM-1 were lower in the experimental group (P<0.05). The treatment efficiency of the experimental group (90.58%) was significantly higher than that of the control group (67.92%) (P<0.05). There was no significant difference in the incidence of adverse reactions between the 2 groups (P > 0.05). Conclusion: The Bozhi Glycopeptide Injection can significantly reduce the serum levels of TNF-α, IL-6, IL-17A, IL-22, INF-γ, VEGF, sE-slelctin and sICAM-1 in patients with large areas of psoriasis vulgaris, inhibit angiogenesis, improve clinical efficacy, and have high clinical efficacy and safety.
		2017 Vol. 23 (12): 1994-1996 [Abstract] ( 300 ) HTML (1 KB) PDF (1396 KB) ( 340 )

	1997	Risk Factors Analysis and Control Measures of Nosocomial Infection in Patients with Cardiology
		MEI Chunlong, XU Yan
		DOI: 10.3969/j.issn.1006-6233.2017.12.018
		Objective: To investigate the distribution of the main parts of hospital infection and the risk factors of infection in hospitalized patients, and to provide the clinical basis for the prevention of nosocomial infection. Methods: 2049 patients admitted in our hospital from January 2015 to December 2016 were retrospectively analyzed. Results: The incidence of nosocomial nosocomial infection was 2.05%. The main part of the hospital infection was respiratory infection. The patients were aged ≥65 years old. They had basic diseases such as diabetes mellitus and hypertension. There were invasive operation, antibiotics and hospital stay ≥14 days and so on, and the difference was statistically significant (P <0.05). Conclusion: It is possible to reduce the hospital infection rate, reduce the average hospitalization time, improve the quality of life of patients and reduce the medical expenses by taking preventive measures and treatment measures as soon as possible to evaluate the risk factors of nosocomial infection in patients with heart medicine hospital.
		2017 Vol. 23 (12): 1997-1999 [Abstract] ( 347 ) HTML (1 KB) PDF (1377 KB) ( 268 )

	2000	Comparison of Blood Lipid, Hcy levels and E-selectin Genotype Distribution in male patients with Coronary Heart Disease
		WANG Liping, SUN Changming, YU Haiming, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.019
		Objective: To compare the blood lipid and Hcy levels and E-selectin genotype distribution in male patients with coronary heart disease. Methods: A total of 190 patients with coronary heart disease were selected from our hospital from Jan. 2015 to Jun. 2017, including Hui 90cases, 100 cases of Han nationality as the research object, using restriction fragment length polymorphism analysis of polymerase chain reaction (PCR-RFLP) gene polymorphism detection of E selectin in the second exon of G89T and the fourth exon of A561C, and serological detection levels in the two groups,to explore the differences between the two peoples. Results:There was no significant difference between Hui and Han population in age, while the Han family history, hypertension, smoking/drinking history was significantly higher than the proportion of Hui population (P<0.05);Group of coronary heart disease in Han population of HDL, Glu, serum TC, Hcy levels were significantly higher than that of Hui population, the difference was statistically significant (P<0.05);Han AMI group serum E-selectin level was significantly higher than that of the Hui, the difference was statistically significant (P<0.05),SAP group and UAP group had no significant difference between the two ethnic groups (P＞0.05);Group GG and GT, the distribution of AMI AA and AC genotype was significantly higher than that of Han and Hui, there was a significant difference (P<0.05),the national SAP and UAP distribution between groups were not significantly different (P＞0.05). Conclusions:Han nationality patients with coronary heart disease in the family history, history of hypertension, smoking/drinking history and the ratio of serum TC, HDL, Glu, Hcy levels Was higher than that of Hui population; E-selectin Exon 2 G98T and Exon 4 A561C two gene polymorphism in Hui and Han nationality coronary heart disease have significant difference, Hui AMI group GT and AC genotype were higher incidence.
		2017 Vol. 23 (12): 2000-2004 [Abstract] ( 300 ) HTML (1 KB) PDF (1416 KB) ( 390 )

	2005	Clinical Effect on Left Atrial Appendage Occlusion with the Amplatzer Cardiac Plug in Atrial Fibrillation Patients with Increased Bleeding Risk
		GUAN Xin, BAI Zhisheng
		DOI: 10.3969/j.issn.1006-6233.2017.12.020
		Objective: To investigate the clinical effect on left atrial appendage occlusion with the amplatzer cardiac plug in atrial fibrillation patients with increased bleeding risk. Methods: 60 atrial fibrillation patients with increased bleeding risk by Left atrial appendage occlusion admitted in cardiology department of our hospital during March 2013 to May 2015 were selected as LAAO group and 80 atrial fibrillation patients with increased bleeding risk for the same period as the control group. The plasma ANP, left ventricular ejection fraction (LVEF) and LAA peak, 1 year and 2 year survival rates were compared of two groups before and after treatment. Results: The plasma ANP level of LAAO Group after 72 h and 3 months postoperative were significantly decreased. After 3 months, the ANP level back to 26.56±5.17 (pg/ml), there was no statistically significant difference compared with control group (P>0.05). and recovered to preoperative levels after 3 months postoperative. Compared with control group, the difference was statistically significant (P<0.05). The cardiac function index of two groups were significantly better than before treatment and the improvement of observation group was significantly better than control group, the difference was statistically significant (P<0.05). The 1 year survival rates (88.3% vs72.5 %)and 2 year survival rates(53.3% vs38.8 %) of two groups were significant difference (P< 0.05). Conclusion: LAAO with ACP seems to improve the combination of survival ,improve heart function and has good application prospect in patients with atrial fibrillation and increased bleeding risk.
		2017 Vol. 23 (12): 2005-2009 [Abstract] ( 226 ) HTML (1 KB) PDF (1353 KB) ( 281 )

	2010	To Investigate the Serum Marker Pregnancy Detection in Prenatal Screening for Down Syndrome
		FU Jiuyuan, XIAO Yanping, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.021
		Objective: To explore the change and clinical significance of serum markers in Down syndrome (Down syndrome,DS) prenatal screening. Methods: The selection from July 2014 to July 2017 in our hospital during the application of quantitative mass spectrometry was used to detect 2598 cases of 14⁺¹~21⁺⁶weeks pregnant women were detected serum AFP、uE3、HCG and InhA markers and content, combined with maternal age, body mass, gestational weeks, single twins, smoking history, whether patients with diabetes, previous factors without abnormal pregnancy history, the use of Teng cheng version of the system risk assessment. Results: The 2598 cases of pregnant women, screening out the abnormal chromosome 117 cases of pregnant women with high risk pregnancy, including 54 cases of pregnant women were amniocentesis antenatal examination, diagnosis of Down syndrome in 21 cases, 2 cases of trisomy 18-syndrome, 3 cases of other fetal chromosomal abnormalities. (1) The levels of AFP and uE3 were lower than that in the low-risk group, [(15.54±1.23)vs.(35.38±3.54) ng/mL] and [(4.16±3.25)vs.(8.31±2.26) ng/mL] , respectively. the difference was significant (P<0.05). The levels of HCG and InhA were higher than that that in the low risk group, [(2.94±1.26)vs.(1.16±3.12) mIU/mL] and [(2.94±1.26)vs.(1.16±3.12) mIU/mL], respectively.(2) The total positive rate of screening for birth defects in the >35-year-old pregnant women (10.08%) was higher in ≤35-year-old pregnant women (3.50%), the difference was significant (P<0.05). (3) The total positive rate of diagnosis of birth defects in high-risk group (65.22%) was significantly higher than that in the low-risk pregnant women (35.48%), the difference was significant (P<0.05). (4) The levels of serum HCG and InhA rise while The levels of serum AFP and InhA reduced in the pregnant women of pregnancy DS fetal. Conclusions: The second trimester serum marker examination can be used as an important index prediction of fetal chromosomal abnormalities, and take effective measures in a timely manner through the prenatal diagnosis, can significantly reduce the birth defects, to help students work.
		2017 Vol. 23 (12): 2010-2012 [Abstract] ( 273 ) HTML (1 KB) PDF (1389 KB) ( 339 )

	2013	Research on the Effectiveness of Bepotastine Hesilate in the treatment of Primary Acquired Cold Urticaria
		TIAN Zhilan, ZHANG Liangqi, HOU Junrong, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.022
		Objective: To evaluate the efficacy and safety of bepotastine besilate in the treatment of primary acquired cold urticaria (PACU). Method: The selected PACU patients were randomly divided into experimental group and control group, were treated with benzenesulfonyl bepotastine besilate and placebo treatment, treatment for two weeks of pruritus and wheal response to cold stimulation test were observed, and the cold water or cold air to stimulate the emergence of clinical symptoms. Result: The itchy wheal reaction cold stimulation test and rewarming in 20 min patients with PACU in cold water or air after the wheal reaction and pruritus compared with the placebo group had significant difference (P<0.05). The incidence of adverse reactions was low. Conclusion: Mizolastine is safe and effective in the treatment of primary acquired cold urticaria.
		2017 Vol. 23 (12): 2013-2015 [Abstract] ( 188 ) HTML (1 KB) PDF (1386 KB) ( 207 )

	2058	Research on the Differences between Blood Samples Anticoagulated Different of Real-time Fluorescent Quantitative PCR method for the Determination of HBV-DNA Results
		ZHANG Jing, LUO Baochang
		DOI: 10.3969/j.issn.1006-6233.2017.12.038
		Objective: To investigate the use of anticoagulants and vacuum without anticoagulant blood samples were collected for real-time fluorescence quantitative (PCR) difference method for detection of hepatitis B virus HBV-DNA results, provide the basis for clinical selection of HBV-DNA specimen collection containers, different types of HBV-DNA specimens analysis results provide the reference for clinicians. Methods: With different anticoagulants and vacuum without anticoagulant blood specimen collection, Extraction of HBV nucleic acids by precipitation boiling cracking method. The content of HBV-DNA was detected by real-time fluorescent quantitative PCR. Results: There was no significant difference in HBV-DNA content between the plasma samples collected from the vacuum collecting vessels with different anticoagulants (P>0.05). However, the plasma levels of EDTA-2K and heparin anticoagulant plasma samples were significantly lower compared with the serum levels of HBV-DNA without anticoagulant (P<0.05). A total of 128 samples were detected, of which 105 samples were collected by three kinds of vacuum blood vessels. The total correlation coefficient (R) of the 105 cases was 0.916 (P<0.01). Conclusions: The content of HBV-DNA in serum samples without anticoagulant is significantly higher than that in anticoagulant plasma samples
		2017 Vol. 23 (12): 2058-2060 [Abstract] ( 226 ) HTML (1 KB) PDF (1392 KB) ( 413 )

	2061	Relationship between Blood Pressure Variability and Microalbuminuria in patients with Primary Hypertension
		YANG Jing, ZHANG Xiaoling, SU Hao, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.039
		Objective: To investigate the relationship of BPV evaluation index: the actual average variation (ARV) and standard deviation (SD) of the pros and cons through the analysis of newly diagnosed patients with essential hypertension blood pressure variability (BPV) and urinary albumin (MA). Method:A total of 223 of primary hypertension patients were selected, averaged (50.9±12.1) years old. all the patients were not taking antihypertensive drugs, according to microalbuminuria divided into positive-MA group (71 case) and negative-MA group (152 case). Baseline data, 24h mean systolic and diastolic pressure, nocturnal systolic and diastolic blood pressure, daytime systolic and diastolic blood pressure, and SD and ARV of the corresponding period were compared, to analyze the relationship between MA and mean blood pressure, SD, ARV, and so on. Result:The SD (24h SBP, dSBP, nSBP), ARV (24hSBP, dSBP) in positive-MA group were higher than the negative-MA group, and there was statistical significance (P<0.05); but SD , ARV of diastolic blood pressure, ARV of nighttime systolic blood pressure are no significant difference between the two groups (P>0.05). ②Logistic regression analysis showed that 24h mean systolic blood pressure, SD of diurnal systolic pressure ,SD of nocturnal systolic blood pressure , ARV of 24h systolic blood pressure were independent risk factors of MA. Conclusion: Blood pressure variability is an independent risk factor for predicting early renal function impairment, and SD and ARV can be used to assess blood pressure variability.
		2017 Vol. 23 (12): 2061-2064 [Abstract] ( 291 ) HTML (1 KB) PDF (1425 KB) ( 227 )

	2065	Study On Anatomical Influencing Factors Of Ⅱ Odontoid Fracture
		XIE Dong, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.040
		Objective: By measuring the some anatomical parameters of odontoid process, and to explore the anatomical factors of odontoid type Ⅱ fractures. Methods:Choosing 25 cases of odontoid CT imaging data of normal anatomical structures, 24 cases of odontoid fracture CT imaging data and fracture displacement <2mm. The posterior slope angle, the side angle, and the transverse diameter and anteroposterior diameter of the base of odontoid were measured using the measurement scale of the PACS imaging system. And comparing the diffe differences between the two groups.Results: The posterior slope angle of normal anatomical structures was 17.56±1.61 °, the left side angle was 118.84±2.78 °, the right side angle was 119.13±3.04°, the transverse diameter of the base of odontoid was 9.73±0.98mm, the anteroposterior diameter of the base of odontoid was 11.97±0.96mm. The posterior slope angle of occurrence of II odontoid fracture was 15.13±1.35 °, the left side angle was 117.97±2.66 °, the right side angle was 119.35±2.13°, the transverse diameter of the base of occurrence of fracture of odontoid process was 9.82±1.21mm, the anteroposterior diameter of the base of odontoid was 9.46±0.89mm. Conclusion: The occurrence of Ⅱ odontoid fracture is related to the posterior slope angle of odontoid process,the smaller the posterior slope angle is, the more prone to fracture. The occurrence of Ⅱ odontoid fractures is related to the anteroposterior diameter of the base of the odontoid process,the shorter the anteroposterior diameter is,the more prone to fracture . Ⅱ odontoid fractures have nothing to do with the left and right side angle and the transverse diameter of the base of odontoid.
		2017 Vol. 23 (12): 2065-2067 [Abstract] ( 237 ) HTML (1 KB) PDF (1433 KB) ( 222 )

	2068	Clinical Application of Aspiration with Hysteroscopy-Laparoscopy in Cornual Pregnancy
		QIANG Yan, LI Yujuan, DONG Lingyan, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.041
		Objective: To study the clinical application of aspiration with hysteroscopy-laparoscopy in cornual pregnancy. Methods: A total of 126 patients with cornual pregnancy who were treated in our hospital from June 2015 to June 2017 were selected and randomly divided into a control group (n=63) and an observation group (n=63). The observation group was treated by aspiration with hysteroscopy-laparoscopy, and the control group was treated by conventional aspiration. The therapeutic effects of the two groups were evaluated based on intraoperative bleeding volume and level of serum β-human chorionic gonadotropin (β-HCG). Results: For the observation group, the markedly effective rate was 39.7%, the effective rate was 52.4%, and the ineffective rate was 7.9%. For the control group, the markedly effective rate was 25.4%, the effective rate was 46.0%, and the ineffective rate was 28.6%. The overall effective rate of the observation group (92.1%) was significantly higher than that of the control group (71.4%) (P<0.05). The intraoperative bleeding volume of the observation group was (57.32 ± 6.52) ml, and the postoperative serum β-HCG level was (4.22 ± 0.51) mIU/ml, which were both significantly lower than those of the control group ((94.32 ± 10.02) ml and (13.71 ± 2.98) mIU/ml) (P <0.05). After treatment, the total satisfaction rate of the observation group (92.1%) was significantly higher than that of the control group (69.8%) (P<0.05). Conclusion: Aspiration with hysteroscopy-laparoscopy in cornual pregnancy significantly reduced intraoperative bleeding volume and serum β-HCG level, and increased the success rate of surgery, thus being of great clinical significance.
		2017 Vol. 23 (12): 2068-2071 [Abstract] ( 238 ) HTML (1 KB) PDF (1386 KB) ( 317 )

	2076	Effect of L-carnitine Combined with Shengmai Injection on Children with Viral Myocarditis and its effect on Serum Cardiac Troponin I and Creatine Kinase Isoenzyme
		XU Hui, NIU Ling
		DOI: 10.3969/j.issn.1006-6233.2017.12.043
		Objective: To investigate the effect of levocarnitine combined with Shengmai injection on the treatment of viral myocarditis in children and the effect of serum cardiac troponin I (cTnI) and creatine kinase isoenzyme (CK-MB). Methods: 100 patients with viral myocarditis enrolled from May 2015 to May 2017 were randomly divided into two groups. The children in the control group were given routine treatment. The patients in the experimental group were treated with levocarnitine combined with Shengmai injection Fluid, compare the two groups of children with TCM symptom score, the overall efficacy of the disease, TCM syndrome, disease-related parameters, cellular immunity and cardiac function. Results: Compared with the control group, CD3, CD4 and CD4 / CD8 were significantly lower than those in the control group (P<0.05) (P<0.01). The overall markedly effective rate of disease was significantly higher than that of the control group (P<0.05). The significant difference was significant (P<0.05). Conclusion: The effect of levocarnitine combined with Shengmai injection on children with viral myocarditis and the effect on cTnI and CK-MB levels is significant.
		2017 Vol. 23 (12): 2076-2078 [Abstract] ( 242 ) HTML (1 KB) PDF (1380 KB) ( 385 )

	2079	Clinical Observation of Deanxit combined with Yi Xin Shu Capsule in the Treatment of Anxiety State after PCI
		ZHANG Jinyan, YIN Yuhua, TAN Liduan
		DOI: 10.3969/j.issn.1006-6233.2017.12.044
		Objective: To explore the clinical curative of deanxit combined with yixinshu capsule in the treatment of patients with anxiety state after PCI. Methods: 120 patients with anxiety in PCI surgery admitted in Chengde central hospital from January 2014 to January 2017 were selected. They were randomly divided into four groups, 27 cases in group A, 37 cases in group B, 23 cases in group C, and 33 cases in group D. Group A was the control group, given standardized treatment of coronary heart disease combined with psychological counseling; group B control group were treated with Deanxit anti anxiety treatment; group C on the basis of the control group plus Yixinshu capsule intervention; D group in the control group based on the combined application of energy-saving and Yixinshu capsule for 4 weeks, four groups were observed in patients with HAMA score, angina and ECG ST-T changes. Results: Patients with treatment by deanxit combined with yixinshu capsule had lower HAMA scores(P<0.05); The per protocol effective rate was 94% for group D, 70.3% for group B, 78.3% for group C. Group D effective rate were significantly higher than group B, group C(P<0.05). Conclusions: Deanxit combined with yixinshu capsule can effectively treat the somatic symptoms of anxiety state after PCI, improve clinical symptoms of coronary artery disease.
		2017 Vol. 23 (12): 2079-2082 [Abstract] ( 202 ) HTML (1 KB) PDF (1387 KB) ( 215 )

	2083	Observation on the Therapeutic Effect of Qian Lie Hua Zhuo Pills Combined with Levofloxacin in Treating Ⅲ A Prostatitis
		CHEN Yingzhong, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.045
		Objective: To observe and evaluate the efficacy of the Qian Lie Hua Zhuo Pills combined with Levofloxacin in the treatment of type ⅢA prostatitis. Methods: One hundred and four patients with type ⅢA prostatitis admitted in our hospital from July 2015 to February 2017, were randomly divided into control group and experimental group. There were Fifty-two cases in each group. The control group received routine treatment, oral Levofloxacin, 0.2 gram/ Time, once daily,and given prostate massage therapy, 1 times / week; experimental group: to give clinical routine treatment while oral Self-made Qian Lie Hua Zhuo Pills, 6gram/ time, two times daily. After 5 weeks of continuous treatment, the curative effect of the two groups was observed and compared the NIH-CPSI score (Pain score, Urinary symptom score, Life quality score), white blood cell (EPS-WBC) in the prostatic fluid, Maximum urinary flow rate changes. Results: The NIH-CPSI scores of the two groups were significantly lower than before treatment (P ＜ 0.05). The overall significant efficiency rate and overall effective rate of the two groups were statistically significant (P ＜ 0.05). The EPS-WBC counts in the experimental group and the control group were significantly lower than before treatment and the difference was statistically significant (P ＜ 0.05). The maximum urinary flow rate of the two groups was significantly higher than that before treatment (P ＜ 0.05). Conclusion: The Qian Lie Hua Zhuo Pills combined with Levofloxacin in the treatment of type ⅢA prostatitis can obviously improve the symptoms of pelvic cavity, perineal pain, urinary frequency, urinary incontinence, sexual dysfunction and so on, alleviate the patients' mental depression and anxiety.
		2017 Vol. 23 (12): 2083-2086 [Abstract] ( 196 ) HTML (1 KB) PDF (1415 KB) ( 164 )

	2087	Clinical Efficacy of Satellite Ganglion Block with Guipi Decoction for Cervical-cardiac Syndrome
		MENG Aixia, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.046
		Objective: To observe the clinical effect of the Guipi decoction combined with stellate ganglion block (SGB) in treating Cervical-cardiac Syndrome. Then provide theoretical basis for the treatment of Cervical-cardiac Syndrome by integrated traditional Chinese and western medicine.Methods: Select 80 cases of Cervical-cardiac Syndrome patients. And divided them into the treatment group and the control group randomly. 41 cases in the treatment group and 39 cases in the group. The treatment group was treated by SGB . The contrd group was treated by the Guipi decoction combined with SGB.One month was a course of treatment. Then appraise the total effective rate of heart-throb、dizziness、chest distress 、chest complaint and the change of bearing premature. Results: The treatment group is better than control group in the total effective rate of clinical symptom.The treatment group can decrease bearing premature obviously( P<0.01). Possess the statistical significance.Conclusions: The Guipi decoction combined with SGB is effective on treating Cervical-cardiac Syndrome,and can be popularized in hospitals of various levels.
		2017 Vol. 23 (12): 2087-2089 [Abstract] ( 185 ) HTML (1 KB) PDF (1388 KB) ( 296 )

	2090	Clinical Observation on the Treatment of Somatic Symptoms combined with Xiaoyao Pill Flupentixol and Melitracen
		ZHAO Wu
		DOI: 10.3969/j.issn.1006-6233.2017.12.047
		Objective: To observe the clinical effect of Flupentixol and melitracen combined with Xiaoyao Pill in the treatment of somatization symptoms. Methods: 98 cases of somatization symptoms in our hospital during the past 2 years were randomly divided into the observation group and the control group, 49 cases in each group. The observation group was given Flupentixol and melitracen tablets, 1 tablets each time, once in the morning. Xiaoyao pills, 8 pills each time, 3 times a day. The control group was given Fluoxetine Hydrochloride Capsules, 20mg, once a day. Treatment was observed for 8 weeks. The curative effect was evaluated by SSS scale at 2 weeks, 4 weeks, 6 weeks and 8 weeks after treatment. Results: at the second weekend of the medication, the SSS score of the observation group and the control group had very significant difference (P<0.01). At the end of the 8 week treatment, the SSS scores of the 2 groups were significantly decreased, but there was still significant difference between the 2 groups (P<0.05). Conclusion: Flupentixol and melitracen combined with Xiaoyao Pill in the treatment of patients with somatization symptoms, has quick effect, good curative effect, adverse reaction and good compliance characteristics.
		2017 Vol. 23 (12): 2090-2091 [Abstract] ( 233 ) HTML (1 KB) PDF (1365 KB) ( 463 )

	2092	Clinical Efficacy on Treatment of Type 2 Diabetes Mellitus Combined with Primary Treatment of Pulmonary Tuberculosis with Jiawei qinjiao biejia Decoction
		WANG Xiuzheng, ZHANG Hao, DIAO Lili, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.048
		Objective: To observe the clinical efficacy of jiawei qinjiao biejia decoction in the treatment of type 2 diabetes mellitus combined with newly diagnosed smear-positive pulmonary tuberculosis. Methods: 300 patients with type 2 diabetes mellitus complicated with newly diagnosed smear-positive pulmonary tuberculosis were randomly divided into two groups. The control group was treated with conventional hypoglycemic and anti-tuberculosis drugs. The treatment group was treated on the basis of the control group jiawei qinjiao biejia decoction and aerosol inhalation treatment, 6 months after treatment to evaluate the clinical efficacy. Results: The levels of FBG, 2hPBG, HbA1c and cough, sputum, wheezing and pulmonary rales in the two groups were lower than those in the control group, the difference was statistically significant (P<0.05), and the treatment group was lower than the control group, the difference was statistically significant (P<0.05). The effective rate of wound healing, cure rate and cure rate were higher in the treatment group than in the control group, the difference was statistically significant (P<0.05). Conclusion: The combination of jiawei qinjiao biejia decoction in the treatment of type 2 diabetes mellitus combined with newly diagnosed smear-positive pulmonary tuberculosis can better control blood sugar, promote sputum negative, lesion absorption and empty closure, and improve cough, sputum, wheezing, lung rales and other clinical symptoms, improve clinical efficacy.
		2017 Vol. 23 (12): 2092-2095 [Abstract] ( 232 ) HTML (1 KB) PDF (1389 KB) ( 237 )

	2104	Effect of High Quality Nursing combined with Health Education on Anxiety and Depression and Postoperative Pain in patients undergoing Gynecological Laparoscopic Surgery
		SONG Xiulan
		DOI: 10.3969/j.issn.1006-6233.2017.12.052
		Objective: To investigate the effect of high quality nursing combined with health education on anxiety and depression and postoperative pain in patients undergoing gynecological laparoscopic surgery. Methods: 120 cases of laparoscopic surgery in our hospital were randomly divided into experimental group and control group, each group had a total of 60 cases. Patients in control group were given routine nursing and health education. The patients in the experimental group received preoperative, intraoperative and postoperative nursing care and health education. The visual analogue scale (VAS), Self rating Anxiety Scale (SAS) and self rating Depression Scale (SDS), and the level of compliance of the patients were observed and compared between the two groups before and after the treatment. Results: Compared with before treatment, VAS, SAS and SDS scores were decreased after treatment, the difference was statistically significant (P<0.05); compared with the control group, the VAS, SAS, SDS score level was lower of experimental group patients, the difference was statistically significant (P<0.05); compared with the control group, the compliance rate was higher of experimental group patients, the difference was statistically significant (P<0.05). Conclusion: High quality nursing combined with health education can significantly reduce the anxiety and depression of patients with gynecological laparoscopic surgery and postoperative pain.
		2017 Vol. 23 (12): 2104-2107 [Abstract] ( 487 ) HTML (1 KB) PDF (1389 KB) ( 243 )

	2108	Study on the Effect of Fenestration on Bone Graft and Bone Grafting by Meticulous Nursing
		ZHAO Juan, ZHAN Yingying, CHEN Menglu, et al
		DOI: 10.3969/j.issn.1006-6233.2017.12.053
		Objective: To investigate the effect of fenestration on bone graft and bone grafting by meticulous nursing. Methods: 74 patients undergoing fenestration bone grafting in our hospital were selected and randomly divided into the control group and the experiment group with 37 cases in each group. The control group was given routine nursing care; the experimental group was given meticulous care on the basis of the above; the two groups were treated with open window bone grafting and bone grafting. The ROM score excellent and good rate, good rate of HSS score, bone healing time, healing time and healing rate of two groups, fracture tenderness disappearance time, longitudinal percussion pain elimination time, nursing service satisfaction, operation compliance were compared between two group. Results: Compared with control group, the excellent and good rate of ROM score and HSS score excellent rate were higher, the disappearance time of fracture tenderness and the elimination time of longitudinal percussion pain were shortened, and the bone healing time was shortened. The rate of primary healing and the two stage healing rate was higher, and the satisfaction degree of patients to nursing service and the score of compliance were higher, the difference was statistically significant (P < 0.05) . Conclusion: Meticulous nursing care for patients with fenestration bone grafting and bone grafting provides a more comprehensive and detailed nursing intervention, which can help to promote bone healing and bone graft growth, good prognosis, suitable for clinical application.
		2017 Vol. 23 (12): 2108-2111 [Abstract] ( 423 ) HTML (1 KB) PDF (1383 KB) ( 234 )

Copyright © Editorial Board of HeBei Med
Supported by:Beijing Magtech