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2017 Vol. 23, No. 4
Published: 2017-04-20
529
Preliminary Study on the Application of Low dose CT Scan and Quantitative Analysis in Patients with COPD
WANG Yongqin, DUAN Yumei, SONG Lihua
DOI: 10.3969/j.issn.1006-6233.2017.04.001
Objective:
To study the low dose CT scanning and quantitative analysis on the value of airway lesions in chronic obstructive pulmonary disease.
Methods:
From August 2015 to July 2016, selected 69 cases of COPD patients admitted in our hospital, according to the severity patients were divided into mild group of 26 cases, moderate group of 19 cases, severe group of 24 cases, and at the same time, choose the health check-up 30 cases as control group. All the research objects were received with low dose CT scanning and lung function test, and measured airway related parameters of the airway with quantitative CT analysis soft ware, and made spearman correlation analysis.
Results:
The contrast of FEV1, FEV1 / FVC of control group, mild group, moderate group and severe group showed a trend of gradual decline, the difference was statistically significance (P < 0.05). The contrast of WA/BSA, T/BSA, WA %, Pi10 of control group, mild group, moderate group and severe group showed a trend of rising, the difference had statistical significance (P < 0.05). FEV1 and WA %, a negative correlation relationship between Pi10 (r = -0.472, P = 0.000; r =- 0.484, P = 0.000), FEV1 / FVC and WA %, were negatively correlated relationship between Pi10 (r = -0.501, P = 0.000; r=- 0.493, P = 0.000).
Conclusion:
Low dose CT scanning and quantitative analysis can provide reliable assessment of COPD airway disease in patients with information, airway parameter WA %, Pi10 is an effective objective evaluation index
2017 Vol. 23 (4): 529-531 [
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105
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532
Efficacy of Los Platinum Combined Eddy Injection for Patients with Malignant Pleural Effusion
ZHU Yali, JI Hong, WANG Xin
DOI: 10.3969/j.issn.1006-6233.2017.04.002
Objective:
To observe the effect of eddy injection combined los platinum pleural perfusion on advanced NSCLC patients with malignant pleural effusion and the influence on serum levels of VEGF.
Methods:
74 cases of patients with malignant pleural effusion with NSCLC admitted in our hospital from April 2013 to June 2015 were divided into control group and observation group according to random parallel grouping, 37 cases in each group. The patients in the control group were treated with intrapleural perfusion of luo platinum. The patients in the observation group were treated with eddly injection on the basis of the control group. The efficacy after treatment of all the patients and its influence on serum levels of VEGF were compared.
Results:
After treatment, the clinical remission rate of the control group (67.5%) was significantly higher than that of the control group (48.6%) (P < 0.05). The VECR level of two groups patients(140.22±19.30ng/L vs105.54±13.48ng/L)after treatment were significantly lower than that before treatment (P < 0.05); the degree of decline in observation group was obviously higher than that of control group (P < 0.05); the incidence of patients in observation group with chest pain, bone marrow suppression was lower than that in control group (P < 0.05).
Conclusion:
The clinical application of los platinum pleural perfusion combined with eddy injection treatment of advanced NSCLC with malignant pleural effusion curative effect significantly, can significantly improve the serum VEGF levels, and high safety and it can be popularized in clinical application.
2017 Vol. 23 (4): 532-534 [
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134
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535
Application of Oseltamivir Combined with Yanhuning in Children with Viral Pneumonia
WANG Xiaohong, LIN Yan, HU Dan, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.003
Objective:
To explore the application of oseltamivir combined with Yanhuning in children with viral pneumonia so as to provide reference for future clinical treatment.
Methods:
60 cases of children with viral pneumonia admitted in our hospital from Jan. 2014 to Oct. 2016 were selected as the research object. By randomly all the patients were divided into 2 groups, control the treatment group was given Yanhuning, the observation group was given oseltamivir combined with Yanhuning treatment, 30 cases in each group. The two groups were observed the clinical efficacy and adverse reaction.
Results:
The observation group R = 0.5278, t = 14.161, the confidence interval (0.4516, 0.6040), the 95% confidence interval does not include 0.05, the difference was statistically significant; The observation group of patients with wheezing; sputum; cough; pulmonary rales disappeared time was shorter than the control group (P < 0.05); The incidence rate of adverse reactions in the observation group was 10.00% significantly lower than 33.33% of the control group (P < 0.05).
Conclusion:
Oseltamivir combined with Yanhuning treatment of children with viral pneumonia can produce a curative effect and can reduce the incidence of adverse reactions. It is worth to have a clinical application and promotion.
2017 Vol. 23 (4): 535-538 [
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277
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539
Evaluation of Curative Effect of Improved Hysteroscopy Combined withLaparoscopy in Treatment of Tubal Infertility Stress Factors and its Effects on Inflammatory Factors
WANG Gaiqin, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.004
Objective:
To study improved hysteroscopy combined with aparoscopy in treatment of tubal infertility stress factors and its effects on inflammatory factors.
Methods:
80 patients of tubal infertility who received therapy from August 2014 to August 2015 in our hospital were selected as research objects. The control group was treated with tradition hysteroscopy combined with aparoscopy, while the observation group was treated with Improved hysteroscopy combined with aparoscopy, Then The stress level of adrenaline (E), cortisol(Cor), Thyroid stimulating hormone(TSH), inflammatory factors interleukin-2(IL-2), interleukin-6(IL-6), interleukin-8(IL-8), C reactive protein (CRP), treatment efficacy before and after treatment two groups of patients were compared.
Results:
After treatment, tubal patency rate, intrauterine pregnancy rate in observation group was than the control group, ectopic pregnancy rate in observation group was less than the control group[92.50%(37/40)vs75.00%(30/40),95.00%(38/40)vs75.00%(30/40),5.00%(2/40)vs22.50%(9/40)] (P＜0.05); E,or in observation group was less than the control group, TSH in observation group was than the control group[(96.16±10.25)ng/ml vs(152.17±16.03)ng/ml、(146.86±18.97)ng/ml vs(236.16±23.17)ng/ml、(3.10±0.50)mU/L vs(1.82±0.32)mU/L] (P＜0.05); IL-2、IL-6、IL-8、CRP in observation group was less than the control group[(17.80±2.21)pg/ml vs(29.07±4.70)pg/ml、(43.21±5.86)pg/ml vs(54.26±6.23)pg/ml、(183.25±34.20)pg/ml vs(213.97±50.65)pg/ml、(5.03±0.81)pg/ml vs(6.12±0.90)pg/ml] (P＜0.05); The total effective rate of observation group was statistically higher than that in the control group95.00%(38/40)vs75.00%(30/40)(P＜0.05).
Conclusion:
To improve the effect of hysteroscopy and laparoscopy in the diagnosis and treatment is well for tubal infertility, which can reduce the expression of stress factors and inflammatory factors, which is beneficial to the prognosis of the patients.
2017 Vol. 23 (4): 539-543 [
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114
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544
Efficacy and Influence of Salbutamol Combined with Ipratropium Bromide in Treatment of COPD and Borg Score
WANG Chunchang, JIN Yang, YANG Cui, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.005
Objective:
To observe the efficacy of salbutamol combined with ipratropium bromide in treatment of chronic obstructive pulmonary disease (COPD).
Methods:
128 patients with COPD were individed into two groups randomly, patients in observation group (n=64) were given salbutamol aerosol joint isopropyl bromide aerosol on the basis of conventional treatment, and patients in control group (n=64) were given salbutamol aerosol on the basis of conventional treatment, two groups'clinical curative effect after 2 period of treatment were compared.
Results:
The total effective rate of observation group was 96.9%, significantly different compared with the control group (P<0.05); The level of VC, FEV1,FEV1/FVC,PEER and PaO2 were significantly higher than the control group (P<0.05),and PaCO
2
was significantly lower than the control group (P < 0.05) after treatment; The Borg score of observation group was better than the control group (P＜0.05).
Conclusions:
Salbutamol combined with ipratropium bromide has a good efficacy in chronic obstructive pulmonary disease. And it is worthy to have a clinical promotion.
2017 Vol. 23 (4): 544-546 [
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123
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547
Value of ABVS in the Treatment of Less than 1cm Breast Hyperplasia Nodules by MMT
WANG Quanle, ZHAO Haijun, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.006
Objective:
To observe the intervention effect of ABVS for hyperplasia of less than 1cm breast nodules with the first automated breast volume imaging (ABVS) score, and then developing ultrasound guided mammotome excision scheme.
Methods:
212 cases of patients were diagonosed less than 1cm nodular hyperplasia with two-dimensional ultrasound in the fourth hospital of Shijiazhuang from January 2014 to 2015 December. All the patients underwent mammotome vacuum biopsy surgery (MMT) received nodular hyperplasia of malignant tendency score firstly, then were compared the effect of the treatment of ABVS positioning before surgery and the effect of MMT operation under the guidance of simple two-dimensional color doppler ultrasound.
Results:
After the treatment of ABVS MMT surgery, the complication rate was obviously lower than that of two-dimensional ultrasound guided MMT surgery, but the difference was not statistically significant (P>0.05); with ABVS score after resection of nodules and pathological results was higher than that of simple two-dimensional ultrasound coincidence rate, there were significant differences (P<0.05).
Conclusion:
Before the MMT treatment of hyperplasia of mammary glands less than 1cm, the ABVS score and localization were performed, which can reduce the incidence of complications, improve the consistency with pathological results, and guide the implementation of the operation plan.
2017 Vol. 23 (4): 547-549 [
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142
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550
Prognostic Value of Neutrophil -lymphocyte Ratio in Critical ill Patients
LI Zhenjie, PU Jun, YUAN Hongbin
DOI: 10.3969/j.issn.1006-6233.2017.04.007
Objective:
To study the prognostic value of neutrophil-lymphocyte ratio (NLR) for predicting prognosis in critical ill patients.
Methods:
Adult patients who admitted our ICU from Jan. 2012 to Sep. 2013 and met inclusion criteria were included. NLR, PCT, APACHEII scores and SOFA scores according to the classification of different outcomes were compared. Univariate and multiple logistic regression analysis were used to identify potential independent risk factors for mortality. The performances of NLR in predicting mortality was assessed by receiver operating curves (ROC) and diagnostic parameters. The survival curves grouped by cut-off value of NLR were compared by using Kapla-Meier method.
Results:
Two hundred patients were included, among which 144 patients were male and the other 56 patients were female. According to classification of different outcomes, NLR in different groups had significant differences (P<0.05). NLR [1.10(1.04-1.16), p<0.001] and APACHEII scores [1.10(1.01-1.20), P<0.001] were the independent risk factors for mortality. The ROC of NLR for predicting mortality was 76.2% and the cut-off value was 4.92. Patients with NLR more than 4.92 had significantly lower survival rates than those with NLR less than 4.92 (P=0.002).
Conclusion:
NLR is an effective predictor of clinical outcomes in critical ill patients.
2017 Vol. 23 (4): 550-554 [
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144
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555
Application of Transvaginal Color Doppler Ultrasound in Diagnosis and Treatment of Uterine Scar Pregnancy after Cesarean Section
ZHONG Suxia, XIE Wenjie, ZHU Wenyan, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.008
Objective:
To evaluate the clinical value of transvaginal color doppler ultrasound in the diagnosis and treatment of uterine scar pregnancy (CSP) after cesarean section.
Methods:
30 CSP patients confirmed by pathology and 30 cases of non CSP patients admitted in our hospital from January 2011 to December 2015 were selected as the research objects. The patients in two groups were separately given transabdominal color doppler ultrasound and transvaginal color doppler ultrasound examination. The clinical and pathological results were the "gold standard". The accuracy, the rate of misdiagnosis and missed diagnosis of two methods were compared.
Results:
The misdiagnosis rate of transabdominal ultrasound and transvaginal ultrasound inspection group were separately 23.33% (7/30) and 6.66% (2/30); the difference was statistically significant (P < 0.05); the misdiagnosis rate of transabdominal ultrasound and transvaginal ultrasound inspection group were 20% (6/30) and 6.66% (2/30); the difference was statistically significant (P < 0.05).
Conclusion:
Transvaginal color doppler ultrasound in the diagnosis of uterine scar pregnancy after cesarean section rate of accuracy is higher than transabdominal color doppler ultrasound examination. It has a lower rate of misdiagnosis and missed diagnosis rate, and can provide accurate therapeutic claims for more patients, make treatment more reasonable, reflect the high value of clinical application.
2017 Vol. 23 (4): 555-557 [
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119
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558
Study on the Effect of Aspirin Combined with Clopidogrel on Acute Ischemic Stroke and the Levels of FIB and Hcy in Serum
XU Mingming, NI Baiyun, XIA Jiaqin
DOI: 10.3969/j.issn.1006-6233.2017.04.009
Objective:
To investigate the effect of aspirin combined with clopidogrel on acute ischemic stroke and the levels of FIB and Hcy in serum.
Methods:
A total of 70 patients with acute ischemic stroke who were admitted to our hospital during July 2015 to July 2016. All the patients were randomized into two groups: the control group (35 cases) used diuretics, cardiac glycoside, aspirin; for the observation group (35 cases), on the basis of the control group treatment, used aspirin combined with clopidogrel. After the treatment for 1 month, the neurologic impairment score and the levels of FIB, Hcy in serum were compared in the two groups and statisticaly analysed in two groups of patients before and after treatment.
Results:
After the treatment, the scores of NIHSS was decreased in two groups; but the observation group was decreased obviously(P<0.05); at the same time, the levels of FIB and Hcy in the observation group were significant lower than the control group after the treatment(P<0.05).
Conclusion:
Aspirin plus clopidogrel in the treatment of acute ischemic stroke can effectively improve patients platelet viscosity, at the same time, reduce the FIB and Hyc level in serum, improve the clinical curative effect and the prognosis; it is worthy of further promotion in clinical treatment.
2017 Vol. 23 (4): 558-560 [
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112
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561
Clinical Value of WBC CRP and PCT in Children with Respiratory Tract Infection Caused by Different Pathogens
LIU Xiaoqiao, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.010
Objective:
To observe the clinical variety of white blood cell count (WBC), C-reactive protein (CRP) and procalcitonin (PCT) of different pathogens causing respiratory infection in children.
Methods:
157 cases of children of respiratory infections in our hospital were chose from January 2015 to May 2016, according to different pathogens, divided into bacteria group, viruses group and mycoplasma group, according to different staining of bacteria groups, divided group G+ and group G-. Analysis of the WBC, CRP and PCT test results and the change of each group before and after the treatment was conducted; a preliminary classification of etiology diagnosis basis was provided.
Results:
The WBC, CRP and PCT in found bacteria group were significantly increased the mycoplasma group and virus group (P < 0.05), while the WBC, CRP and PCT between virus group and mycoplasma group were no significant difference. WBC and CRP on group G+ and G- group, there was no significant difference (P > 0.05), but PCT on G+ group is significantly increased than G- group (P < 0.05). Diagnosis accuracy rate of PCT on children respiratory tract bacterial infection is significantly higher than the WBC and CRP (P < 0.05). The diagnosis of respiratory tract bacterial infection in children by PCT had high specificity and low false positive rate.
Conclusion:
The WBC, CRP and PCT test can preliminary judgment different pathogens to children respiratory infection, for bacterial infections, the diagnostic value of PCT is superior to the WBC and CRP.
2017 Vol. 23 (4): 561-563 [
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116
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564
Efficacy Analysis of Ulinastatin Combined with Continuous Venous Hemodialysis in the Treatment of Severe Acute Pancreatitis
WANG Qi, LU Chengkang, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.011
Objective:
To investigate the efficacy of ulinastatin combined with continuous intravenous hemodialysis in the treatment of severe acute pancreatitis.
Methods:
80 patients with severe acute pancreatitis who were enrolled from January 2014 to November 2016 were randomly divided into two groups. The patients in the control group received continuous intravenous hemodialysis and hemodialysis. The patients in the experimental group received ulinastatin combined with continuous intravenous hemodialysis. The disease-related parameters, clinical symptoms remission rate, remission time and overall treatment of two groups patients before and after treatment were compared.
Results:
The scores of Scr, BUN, TBil, ALT, Lac and CRP in the experimental group were significantly lower than those in the control group (P <0.01); The total effective rate was significantly higher than the control group, there was a significant difference (P <0.05).
Conclusion:
Ulinastatin combined with continuous static - venous hemodiafiltration in the treatment of severe acute pancreatitis is significant, with reference.
2017 Vol. 23 (4): 564-567 [
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146
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568
Predictive Value of MODS Scoring System on Prognosis of Critically ill Patients with Department of Critical Care Medicine in APACHEⅡ Score
LI Huizhen, ZHANG Haiying, ZHAO Yanling
DOI: 10.3969/j.issn.1006-6233.2017.04.012
Objective:
Predictive value of APACHEII score on prognosis of critically ill patients in ICU and APACHEII scoring system for predicting prognosis of critically ill patients in emergency internal medicine in MODS score.
Methods:
APACHEII score and MODS score of 300 critically ill patients in emergency internal medicine were calculated and the mortality was calculated.
Results:
T he use of the number of deaths of APACHEII score and MODS score were higher than the number of people living, the differences were statistically significant (P < 0.05); using the APACHEII score to predict all patients, MODS group and MODS group, APACHEII score increased with the severity of disease, the patients in the MODS group APACHEII the highest score, the difference between groups were statistically significant (P < 0.05). The actual mortality in the study was 26.67%, and the estimated mortality rate was about 30.15%, with no significant difference (P > 0.05). No actual mortality in group MODS was 12.12%, lower than the expected mortality rate of 18.67%, the actual mortality of patients in the MODS group was 75.36%, significantly higher than the expected mortality rate of 46.17%, the difference between the two groups were statistically significant (P < 0.05).
Conclusion:
APACHEII can predict mortality and risk of disease, but the prediction results for patients with MODS are not very satisfactory. The MODS score is more inclined to the evaluation of organ function. The APACHEII scoring system introduced MODS scoring system, can improve the integrity and accuracy of prediction, which has a good effect for the treatment and monitoring of emergency internal medicine in critically ill patients, can control the disease effectively, reduce disease mortality
2017 Vol. 23 (4): 568-571 [
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118
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572
Effect of Immediate Dilation of Phenylephrine and Hydroxyethyl Starch on Maternal Hemodynamics and Fetal pH Value During Cesarean Section Under Combined Spinal Epidural Anesthesia
TIAN Hang, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.013
Objective:
To explore the effect of maternal hemodynamics and fetal acid-base values of immediate expansion of hydroxyethyl starch and phenylephrine hydrochloride on combined spinal-epidural analgesia.
Methods:
According to the different ways of dealing with hypotension,51 cases of elective cesarean section under combined spinal-epidural analgesia were divided into two groups: Phenylephrine hydrochloride group (group P) and Hydroxyethyl starch immediate expansion group (group C). Mean arterial pressure, heart rate, standard volume of output and cardiac output (CO) at the time of anesthesia and post anesthesia between the two groups were compared. The blood gas results of umbilical vein blood of the two groups were compared. Apgar scores at 1 min and 5 min after delivery, and the time from anesthesia to neonatal delivery (IDI) of the two groups were compared.
Results:
There was no significantly difference of mean arterial pressure, cardiac output and cardiac output between the two groups (P> 0.05). The heart rate of the two groups were increased and then decreased, then increased. The heart rate of group C was significantly lower than that of group P at T
2
, T
3
, T
4
, T
5
, T
6
, T
7
and T
8
(P <0.05). The levels of pH, PO
2
, PCO
2
and HCO
3
in the umbilical vein blood of the two groups were all within the normal range, there was no significantly difference between the two groups (P>0.05). The duration of cesarean section, and Aparg score at 1 minute and 5 minutes after umbilical cord cut short were no significantly difference (P> 0.05).
Conclusion:
Combined spinal-epidural analgesia with hydroxyethyl starch immediate expansion can obviously reduce the hypotension at elective cesarean section; deoxidation adrenaline can maintain the maternal systemic stability, and does not increase heart work, little influence on newborn blood gas analysis
2017 Vol. 23 (4): 572-575 [
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115
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576
Effect of Neuromuscular Electrical Stimulation on the Efficacy and Quality of life in Patients with Dysphagia after Stroke
LI Yan
DOI: 10.3969/j.issn.1006-6233.2017.04.014
Objective:
To observe the effect and life quality of stroke patients with dysphagia treated by Neuromuscular Electrical Stimulation (NMES) combined with traditional therapy.
Methods:
The stroke patients with dysphagia treated from Apr. 2013 to Mar. 2015 in our hospital were recruited as the research samples. According to the intensity and frequency of electrical stimulation, those samples divided into 2 subgroups, A and B. Group A was adopted the NMES at a motor level plus traditional therapy, while group B was adopted the NMES at a sensory level plus traditional therapy. All of those patients were followed up and assessed clinically at before treatment, 1 month after treatment and 3 months after treatment, respectively. We observed their FOIS score, SWAL-QOL score and MDADI score.
Results:
FOIS score, SWAL-QOL score and MDADI score were all improved significantly 1 month after treatment. Meantime, those indexes all maintain at a high level after 3 months after treatment. Compared to the before treatment, the 11 dimensions of SWAL-QOL scale, including appetite, food choice, eating time, symptom frequency, psychological burden, fear, language communication, mental health, fatigue, sleep, and social interaction, were all changed significantly. The 4 dimensions of MDADI scale in Overall, physiology, function and emotion were significant different before and after treatment.
Conclusion:
The 2 levels of NMES combined with traditional therapy can both improve the effect of the stroke patient with Dysphagia, and enhance a high quality life
2017 Vol. 23 (4): 576-579 [
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98
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580
Effect and Influence of Erythropoietin and Methylprednisolone on Acute Interstitial Nephritis patients and IL-6 TNF- alpha
LIU Suijun, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.015
Objective:
To study effect and its influence of interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α) of erythropoietin and methylprednisolone in the treatment of patients with acute interstitial nephritis.
Methods:
96 patients with AIN who were treated in our hospital from January 2015 to December 2016 were selected as study object. The patients were divided into observation group and control group with 48 cases in each group. The two groups were discontinued may lead to AIN drugs, and corrected the acidosis, while maintained the body of water electrolyte balance. The control group was given methylprednisolone, modified Chengponisong oral in the treatment of 3d, the observation group was another given EPO for treatment. Two groups were treated for 1 month then compared the comparison of efficacy, clinical indicators, adverse reactions, and the two groups before treatment and after treatment of IL-6 and TNF-α level.
Results:
The effective rate of the observation group was 43.75%, and the total effective rate was about 97.92%, respectively compared with the control group of 16.67% and 83.33% were significantly higher, the difference was statistically significant (P < 0.05). In the observation group, the time of oliguria, the time of polyuria, the time of disappearance of hematuria and proteinuria, and the recovery of renal function to normal were significantly less than those in the control group, the difference was statistically significant (P < 0.05). After treatment, the levels of IL-6 and TNF-α in two groups were significantly lower than those before treatment, and the observation group was lower than the control group, the difference was statistically significant (P < 0.05). The total incidence of adverse reactions in the observation group was 10.42%, compared with the control group of 12.50%, the difference was not statistically significant (P > 0.05).
Conclusion:
The application of EPO and methylprednisolone on the curative effect of treatment of AIN patients with better implementation of the high safety, reduce the release of inflammatory cytokines and anti-inflammatory action. It is worthy of application and popularization.
2017 Vol. 23 (4): 580-583 [
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112
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584
Clinical Significance of Liposuction in Axillary Lymph Node Dissection for Breast Cancer
XIE Fang, NI Jinbin, ZHENG Yanyu, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.016
Objective:
To explore the clinical significance of liposuction in axillary lymph node dissection of breast cancer.
Methods:
120 female patients who underwent modified radical mastectomy were randomly divided into observation group and control group. In the observation group, axillary lymph nodes were dissected after liposuction. The control group received traditional axillary lymph node dissection. Contrastive analysis was made between two groups: operation time, blood loss, number of lymph nodes, postoperative drainage, average extubation days, limb pain, shoulder movement disorders and limb edema.
Results:
In observation group, the average 19 lymph nodes per patient, much more than the control group of 13 ; the blood loss and postoperative drainage, less than the control group; mean extubation time earlier than the control group; However, the operation time was longer than the control group(P<0.05). 4 cases observed of limb pain, 18 cases in the control group; shoulder movement disorders observation group 3 cases, 15 cases in the control group; 1 case occurred limb edema in observation group, in the control group had 8 cases of upper limb edema, postoperative complications were significantly differences (P <0.05).Subgroup analysis showed that the method can achieve better results in obese patients.
Conclusions:
The efficacy for liposuction in the axillary lymph node dissection of breast cancer has the following advantages: clearly exposed armpit, remove adequate lymph nodes, less nerves, blood vessels and lymphatic vessels injured, and fewer postoperative complications, is worthy of clinical further promotion
2017 Vol. 23 (4): 584-588 [
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157
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589
Effects of Different Doses of Propofol on Cognitive Function in Elderly Patients Undergoing Painless Gastroscopy
WEN Huahai, RAN Rui, TIAN Jiangtao
DOI: 10.3969/j.issn.1006-6233.2017.04.017
Objective:
To investigate the influence of different doses of propofol anesthesia in painless gastroscopy in elderly patients with cognitive function
Methods:
200 cases of elderly patients admitted in our hospital from January 2013 to January 2015 were selected as study subjects. All the selected cases were randomly divided into group A, group B, group C and the common gastroscopy group, with 50 cases in each group. The patients in painless gastroscopy group A were recived intravenous injection of 1 mg/kg propofol. The patients in group B were recived intravenous injection of 1.5 mg/kg propofol. The patients in group C were injected with 2 mg/kg propofol for gastroscopy. The patients in the ordinary gastroscopy group only received gastroscopy and mucilage mucilage. The mean arterial pressure (MAP), heart rate (HR), respiratory rate (BR) and oxygen saturation (SPO
2
) of patients were compared during operation. It was recorded and compared four groups of patients with Montreal cognitive assessment scale (MoCA) and activity of daily living scale (ADL) and mini mental state examination (MMSE) score scale after 1 year. The adverse reactions and the incidence of cognitive dysfunction (POCD) in 1 group were compared and observed between the four groups.
Results:
At different time points, the changes of MAP, HR and BR in the painless gastroscopy group were decreased in a dose-dependent manner, and the MAP, HR and BR values of painless gastroscopy group C were significantly lower than those of painless gastroscopy group A (P<0.05). On T1, T2, MAP, HR and BR values of each group were significantly lower than that of painless gastroscopy group A (P<0.05). There was no significant difference in SPO
2
values between the groups (P>0.05). After discharge for 1 years, the MMSE, MoCA and ADL scores of painless gastroscopy group C and were statistically significant (P<0.05). The adverse reaction rate of C group was significantly higher than that in painless gastroscopy group A group, B group and common gastroscopy group (P<0.05). The incidence of POCD in painless gastroscopy group was significantly higher than that in A group, B group and C group (P<0.05).
Conclusion:
Low dose propofol painless gastroscopy has little effect on the cognitive function of elderly patients has clinical value
2017 Vol. 23 (4): 589-593 [
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140
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594
Clinical Value of HRCT Combined with Pulmonary Function Examination in the Diagnosis of Connective Tissue Disease-Related Pulmonary Interstitial Lesions
LIANG Zhiqiang, JIANG Fengyun, ZHAO Lei, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.018
Objective:
To investigate the clinical value of HRCT combined with pulmonary function test in the diagnosis of connective tissue disease associated with interstitial lung disease (CTD-ILD).
Methods:
CTD-ILD was performed in 42 CTD-ILD patients from Jan. 2015 to Dec. 2015. CTD-ILD was performed in 33 patients with CTD alone, and CTD was performed in healthy subjects at the same time. Thirty cases were taken as control group. All the patients were scanned by high resolution CT (HRCT) and lung function was examined. The lung function of the three groups was compared and the application of pulmonary function test in the diagnosis of CTD-ILD was analyzed.
Results:
Compared with CTD group and control group, the total lung CTD-ILD group (TLC), forced vital capacity (FVC), forced expiratory volume (FEV1) were significant differences (P < 0.05); the CTD group and the control group had no significant difference compared to the lung function index. Among the 42 patients with CTD-ILD, 30 cases were detected by HRCT, the detection rate was 71.4%, and 12 cases of HRCT were not detected in 11 patients The combined detection rate was 97.6%, and the detection rate of HRCT was significantly higher than that of HRCT, the difference was statistically significant (P<0.05).
Conclusion:
HRCT combined with pulmonary function test for the diagnosis of connective tissue disease-related interstitial lung disease can effectively improve the detection rate, connective tissue disease patients with pulConmonary function suggest that pulmonary interstitial lesions may occur, it should cause clinical attention
2017 Vol. 23 (4): 594-596 [
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112
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597
The value of contrast-enhanced ultrasound and conventional ultrasound in the diagnosis of gallbladder adenomyomatosis
Chen Yu, Luo Xiaoyong, Wu Hang,Lu Wei
DOI: 10.3969/j.issn.1006-6233.2017.04.019
Objective:
To investigate the clinical value of contrast-enhanced ultrasonography and conventional ultrasound in the diagnosis of gallbladder adenomyomatosis(GA).
Methods:
The clinical in 28 patients with gallbladder adenomyomatosis in our hospital from January 2012 to January 2015 were included,all were diagnosed by pathology,were treated by conventional ultrasound and contrast-enhanced ultrasound respectively,and compared the image characteristics of two kinds of examination,summed up the two kinds of diagnosis of adenomyomatosis of the accurate rate.
Results:
Conventional ultrasound examination showed that all patients with gallbladder adenomyomatosis showed gallbladder wall thickening(local) signs,the lesion boundaries:0.7mm * 0.4mm * 2.6mm * 1.3mm.The typical manifestation of the gallbladder wall was a flat thickening(local),scattered within the small echo,the individual with strong echo,the rear "comet tail" sign;according to the diagnostic accuracy rate was 67.9%(19/28).Contrast enhanced ultrasound showed that the arterial and venous phases showed inhomogeneous enhancement,and there was a small and no enhancement in the interior;The diagnostic accuracy rate was 96.4%(27/28).The accuracy of contrast-enhanced ultrasound was significantly higher than that of conventional ultrasound(X2=7.79,P<0.05).
Conclusion:
The use of conventional ultrasound and contrast-enhanced ultrasound in the diagnosis of gallbladder adenomyomatosis,the image has its own characteristics,which can effectively improve the accuracy of clinical diagnosis,and has the value of promotion
2017 Vol. 23 (4): 597-599 [
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202
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600
Effect of Interferon on Herpes Zoster and its Effect on Cellular Immune Function
WU Rile, REN Yu, YU Tao, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.020
Objective:
To study the effects of interferon treatment of herpes zoster and its impact on cellular immune function in patients.
Methods:
90 patients with herpes zoster treated in our hospital from December 2013 to December 2014 were randomly divided into observation group and control group, 45 cases in each. The control group was treated with valacyclovir therapy. The observation group was treated with interferon and valacyclovir therapy. The level of CD3,CD4 and CD8 were compared after 4 weeks, and pain relief time, blistering time, scab off time and crusting time were compared. The PNH rate of the two groups was compared after three monthes.
Results:
The total effective rate was 97.78% in the observation group patients, which were higher than 77.78% in the control group of patients, the difference was statistically significant (P <0.01). Pain relief time (2.24 ± 0.56) d, blistering time(1.56 ± 0.69) d, crusting time (4.58 ± 1.04) d and the scab off time (7.26 ± 1.48) d in the observation group of patients were shorter than pain relief time (5.69 ± 0.58) d, blistering time (3.02 ± 0.82) only d, crusting time (6.89 ± 1.07) d and the scab off time (13.65 ± 1.57) d in the control group of patients, a statistically significant difference (P <0.01). After treatment, CD3 levels (66.38 ± 7.62)× 10
-2
, CD4 levels (39.71 ± 7.55) × 10
-2
, CD8 levels (29.67 ± 7.23) × 10
-2
and CD4 / CD8 levels (1.49 ± 0.16 ) × 10
-2
CD3 levels in the observation group of patients were higher than CD3 levels(58.97 ± 8.36) × 10
-2
, CD4 levels (32.30 ± 7.69) × 10
-2
, CD8 levels (25.34 ± 7.22) × 10
-2
and CD4 / CD8 levels (1.19 ± 0.14) × 10
-2
in the control group of patients, the difference was statistically significant (P <0.01). Occur in patients with postherpetic neuralgia in the observation group was 6.67% lower than the 31.11% of patients in the observation group, the difference was statistically significant (P <0.01).
Conclusion:
Interferon treatment of herpes zoster can improve immune function in patients, and prevention of post-herpetic neuralgia patients
2017 Vol. 23 (4): 600-602 [
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160
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603
Clinical Observation of Different Surgical Repair of Inguinal Hernia in Adults
XIAO Qiang, ZENG Jun, LIANG Haifei, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.021
Objective:
To investigate the clinical effect and safety of transabdominal preperitoneal (TAPP), totally exntraperitoneal prosthesis (TEP) and open tension free hernia repair (Rutkow) in the treatment of adult inguinal hernia.
Methods:
Clinical data of 936 cases (1116 sides) of adult inguinal hernia treated in our hospital from January 2009 to January 2016 were analyzed retrospectively. The patients were divided into TAPP group, TEP group and open group, according to different treatment methods, 152 cases (174 sides), 336 cases (449 sides) and 448 cases (493 sides), respectively. The operation time, the VAS pain score at first day of postoperative, length of stay, postoperative complications of two groups were observed. After 6～40 months (media 21 months) follow up, the recurrence of two groups were observed.
Results:
Operation time: unilateral hernia: TAPP group > TEP group > open group, the difference was statistically significant (P < 0.05). Bilateral hernia: TAPP and open group > TEP group, the difference was statistically significant (P < 0.05), there was no significant difference between the TAPP group and the open group (P > 0.05). Length of stay: the open group was significantly longer than the TAPP group and TEP group (P < 0.05), while there was no significant difference between the TAPP group and the TEP group (P > 0.05). Incidence of complications: open group > TAPP group and TEP group, the difference was statistically significant (P < 0.05), there was no significant difference between TAPP group and TEP group (P > 0.05). The recurrence rate of open group was 0.89%, the recurrence rate of TAPP group was 0.66%, the recurrence rate of TEP group was 0.60%, and there was no significant difference in recurrence rate between the three groups (P > 0.05). The postoperative urinary retention, chronic pain or numbness in the open group were higher than those in the TAPP group and TEP group (P < 0.05).
Conclusion:
TAPP and TEP in the treatment of adult inguinal hernia is satisfactory, especially in the treatment of bilateral inguinal hernia, can significantly reduce the degree of postoperative pain, shorten the length of stay, reduce postoperative urinary retention, chronic pain or numbness, and other complications
2017 Vol. 23 (4): 603-606 [
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136
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607
The Effect of Optimized Motor Skill Training on the Recovery of Hand Function in Stroke Patients
YAO Jie, ZHANG Shaoru, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.022
Objective:
To explore the optimal recovery of motor skills in fine hand function in patients with stroke in the role.
Methods:
60 cases stroke patients admitted in our hospital were randomly divided into two groups, the control group was treated by traditional rehabilitation, research group was used the optimized motor skills training, after treatment for 6 weeks, Fugl-Meyer score, hand, upper extremity function in neural function defect score and a simple inspection score before and after treatment were compared.
Results:
After treatment, the FMA score of the study group was (38.13 ± 7.94), and the STEF score was (58.24 ± 7.83), which was higher than those in the control group (29.92 ± 8.57), (49.87 ± 8.31), the difference was statistically significant (t=3.849,4.015, P < 0.001). The score of neurological deficits in the study group was (2.41 ± 0.88), was significantly lower than the control group (3.51 ± 0.75) points, the difference was statistically significant (t=5.211, P < 0.001).
Conclusion:
The optimized motor skills training can effectively improve the situation of upper extremity in stroke patients with hemiplegia, can promote the recovery of fine hand function in stroke patients, it is worth spreading
2017 Vol. 23 (4): 607-609 [
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101
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610
Analysis of Clinical Efficacy of Behavioral Therapy in Patients with Schizophrenia
GAO Haijiang, CHEN Yanhua, WANG Xingsheng, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.023
Objective:
To explore the clinical application of behavior therapy combination in schizophrenia.
Methods:
369 cases of schizophrenia patients admitted in Jiulongshan hospital of qinhuangdao city from April 2012 to April 2015 were selected as the research objects. All patients were randomly divided into two groups, the treatment group was treated with risperidone combined with risperidone, and the treatment group was treated with risperidone for 8 weeks for the first time in 184 cases. The positive and negative symptom scale (PANSS) was used to evaluate the therapeutic effect. Adverse reaction scale (TESS) and extrapyramidal side effects scale (RSESE) were used to evaluate adverse reactions.
Results:
The clinical efficacy of the study group was better than that of the control group. The total effective rate of the two groups was statistically significant (P<0.05). There were significant differences in the PANSS scores between the two groups during the treatment period (P<0.05). The adverse reactions in the study group were lower than those in the control group (P<0.05).
Conclusion:
The clinical effect of the combination of behavioral therapy in schizophrenia is obvious, and the adverse reaction is low
2017 Vol. 23 (4): 610-612 [
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118
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613
Effect of Probiotics Combinated with Quadruple Chemotherapy in the Eradication of Helicobacter Pylori
ZHANG Bing, WANG Yanling, LI Bingqing, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.024
Objective:
To investigate the effect of probiotics in the eradication of Helicobacter pylori.
Methods:
122 cases of Hp positive patients were selected and were randomly divided into three groups. Group A were received quadruple chemotherapy for 14 days, group B were receved bifidobacterium tetravaccine tablets combinated with quadruple chemotherapy for 14 days, group C were receved bifidobacterium tetravaccine tablets 14 days.
Results:
Group A and group B were better than group C in the eradication rate of Hp, and group B receivce the highest eradication rate of Hp. Group B possess absolute advantage in the prevention of reinfection rate of Hp.
Conclusion:
The application of Bifidobacterium quadruple viable tablets alone can not improve the eradication rate of Hp, and its combination with quadruple therapy can significantly improve the rate of Helicobacter pylori eradication, and can significantly reduce the long-term Hp reinfection rate
2017 Vol. 23 (4): 613-615 [
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117
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616
Analysis of the Effect of Pre-hospital Anticoagulant Therapy on the Prognosis of Patients with Myocardial Infarction with ST Segment Elevation
FAN Conghua
DOI: 10.3969/j.issn.1006-6233.2017.04.025
Objective:
To observe the effect of pre-hospital antiplatelet therapy on the prognosis of patients with myocardial infarction with ST-segment elevation.
Methords:
56 patients with ST-segment elevation acute myocardial infarction admitted to our hospital from March 2014 to February 2016 were randomly divided into observation group (pretreated anticoagulant therapy) and control group (routine treatment ), with 28 patients in each group. The results of prehospital and post-hospital resuscitation were evaluated. the levels of plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI- 1), and record the occurrence of cardiovascular events and adverse reactions were compared.
Results:
The effective rate of pre-hospital rescue was 96.43% in the observation group and 92.86% in the control group, the difference was not statistically significant (x2=0.35, p=0.55); the effective rate of the observation group was 92.86%, and the effective rate was 92.86% in the control group. The difference was not statistically significant (x2=0, p=1.00). The level of t-PA expression in observation group was higher than that in control group (t=3.53, p=0.00095), and the level of PAI-1 was lower than that of control group (t=2.51, p=0.016). The incidence of gastrointestinal discomfort (x2=0.09, p=0.76), ecchymosis (x2=0.12, p=0.73) and gastrointestinal bleeding (x2=0.18, p=0.67) were not statistically different between the two groups. The incidence of cardiovascular events in the observation group was 12.00%, which was significantly lower than that in the control group (41.67%). The difference was statistically significant (x2=5.53, p=0.019).
Conclusion:
Pre-hospital anti-platelet therapy can reduce the incidence of cardiovascular events in patients with ST-segment elevation myocardial infarction and improve the patients'fibrinolysis imbalance without increasing the side effects. It is worthy of clinical application
2017 Vol. 23 (4): 616-619 [
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110
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645
Over-expression of Hsp72 Induced by Hepatitis C virus: Role of Hsp72 in Proliferation of Hepatocellular Carcinoma with HCV Infection
WANG Xi, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.034
Objective:
To investigate the expression of Heat shock protein 72(Hsp72) in HCV infection and its role on the growth and proliferation of hepatocellular carcinoma cells with hepatitis C virus (HCV) infection.
Methods:
Sera and liver biopsy specimens from patients chronically infected with HCV were obtained for analysis of Hsp72 expression by ELISA, quantitative PCR and immunohistochemical staining. Hepatocytes upon infection with cell culture-grown HCV J6/JFH1 were used to investigate the role of over-expressed Hsp72 in proliferation of hepatocellular carcinoma cell with HCV infection by siRNA and cell proliferation assays.
Results:
Hsp72 expression was significantly upregulated in HCV infection. HCV increases Hsp72 expression level via induction of NFAT5. Hsp72 promotes proliferation of human hepatocellular carcinoma cells with HCV infection. The MAPK/MEK activation and cell proliferation driven by Hsp72 were suppressed by MEK inhibitor PD98095.
Conclusions:
The over-expressed of Hsp72 in HCV related HCC contributes to cell proliferation by activating MEK/Erk1/2. The role of Hsp72 and its importance for elimination of HCV in patients with HCC needs to take into account
2017 Vol. 23 (4): 645-650 [
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90
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651
Study on the Effect of Buguzhi Decoction on Wnt/PPARγ Signal Pathway in Healing Process of Fracture in Type 2 Diabetic Rats
CAO Daning, YANG Chunhua, LI Cong
DOI: 10.3969/j.issn.1006-6233.2017.04.035
Objective:
To analysis the effect of Buguzhi Decoction on Wnt/PPARγ signal pathway in healing process of fracture in type 2 diabetic rats.
Methods:
Seventy-two healthy male SD rats were randomly divided into control group, model group, sodium fluoride and Buguzhi group, each with 18 rats. The tibial fracture model was established in control group, type 2 diabetic tibial fracture model were established by intraperitoneal injection of streptozotocin in the other groups, and were given corresponding drug treatment. The tibia BMD, FPG and serum Ca、P、ALP levels, tibia bending strength and torque, the expression levels of β-catenin, p-GSK3β and PPARγ in bone tissue were detected.
Results:
After treatment, compared with model control group, the tibia BMD levels were higher in rats of each group,and Buguzhi group was higher than sodium fluoride group(P<0.05);the serum Ca、P levels were lower in rats of each group,and Buguzhi group was lower than sodium fluoride group (P<0.05);the serum ALP levels were higher in rats of each group,and Buguzhi group was higher than sodium fluoride group (P<0.05);the tibia bending strength and torque levels were higher in rats of each group,and Buguzhi group was higher than sodium fluoride group (P<0.05);the expression of β-catenin protein in bone tissue of rats in each group was higher in rats of each group, and Buguzhi group was higher than sodium fluoride group (P<0.05);the expression of p-GSK3β protein in bone tissue of rats in each group was lower in rats of each group, and Buguzhi group was lower than sodium fluoride group (P<0.05);the expression of PPARγ protein in bone tissue of rats in each group was lower in rats of each group, and Buguzhi group was lower than sodium fluoride group (P<0.05).
Conclusions
: Buguzhi Decoction can effectively improve the BMD、serum ALP levels of fracture and type 2 diabetic rats, reduce serum Ca、P levels, improve the biomechanical strength of bone, accelerate fracture healing, it may be associated with up regulation ofβ-catenin protein expression, down regulation of p-GSK3β、PPARγ protein expression, activation of the Wnt signaling pathway and inhibition of the PPAR signaling pathway
2017 Vol. 23 (4): 651-655 [
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136
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656
Expression of PTTG and VEGF-C in Laryngeal Squamous Cell Carcinoma and its Correlation with Clinicopathological Features
Gao Lisheng, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.036
Objective:
To investigate the expression of PTTG and VEGF-C in laryngeal squamous cell carcinoma and the relationship with the pathological features.
Methods:
Immunohistochemistry and RT-PCR were adopted to detect the expression of PTTG and VEGF-C in 60 cases of laryngeal squamous cell carcinoma and 32 cases of para-carcinoma tissue.
Results:
The expression of PTTG and VEGF-C in laryngeal squamous cell carcinoma were significantly higher than that in para-carcinoma tissue (P<0.01). In laryngeal squamous cell carcinoma, the expressions of PTTG and VEGF-C were associated with differentiation, Lymph node metastasis and clinical stage (P<0.01).
Conclusion:
PTTG and VEGF-C might play an important role in the development of laryngeal squamous cell carcinoma. PTTG and VEGF-C might be prognostic factor of lymph node metastasis
2017 Vol. 23 (4): 656-658 [
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112
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659
Expression of Cyclooxygenase-2 and Proliferating Cell Nuclear Antigen in Bladder Leukoplakia
CHEN Lezhong, TIAN Xiaoyuan, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.037
Objective:
To explore the expression and clinical significance of cyclooxygenase-2 and proliferating cell nuclear antigen in bladder leukoplakia.
Methods:
The expressions of cyclooxygenase-2 and proliferating cell nuclear antigen in 26 cases of bladder leukoplakia and 26 cases of normal urothelium and 26 cases of bladder carcinoma were detected by immunohistochemistry S-P method.
Results:
Two kinds of protein expression in normal urothelial were occasional, the expression of cyclooxygenase-2 in bladder leukoplakia was 46.15% and bladder cancer was 76.92%, the expression of proliferating cell nuclear antigen in bladder leukoplakia was 53.84% and bladder cancer was 69.23%.
Conclusion:
The expression of cyclooxygenase-2 and proliferating cell nuclear antigen is correlated with the occurrence of bladder leukoplakia, and the occurrence and progression of bladder leukoplakia may be related to the occurrence of bladder cancer.
2017 Vol. 23 (4): 659-661 [
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81
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662
Efficacy of Xuebijing in the Treatment of Severe Pneumonia caused by Acinetobacter Baumannii Resistant to Bauman
BAI Yan, MA Xin, ZHENG Jingjing, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.038
Objective:
To investigate the clinical efficacy of Xuebijing injection in the treatment of severe pneumonia caused by acinetobacter baumannii (Bauman).
Method:
140 patients with severe pneumonia admitted in our hospital ICU from 2014 to 2016 were selected as the objects. All the patients were randomly divided into two groups, the observation group (n=74) and the control group (n=66), which were induced by the drug resistant Acinetobacter baumannii. The observation group was treated with Xuebijing injection combined with antibiotics, while the control group was only treated with antibiotics. The clinical efficacy of the two groups were observed and compared.
Results:
2 weeks as a course of treatment, after the same course of treatment, the significant efficiency and efficiency of the observation group were 62.16%, 31.08%, the total effective rate was 93.24%; in the control group, the significant efficiency and effective rate were respectively 48.48% and 24.24%. PO2, pCO2 and WBC were compared between the two groups before and after treatment. Compared with the control group, the observation group decreased WBC (p<0.05), white blood cell count recovered to the normal range, reduce carbon dioxide partial pressure (p<0.05), oxygen partial pressure (p<0.05), to improve the level of patients with improved breathing.
Conclusion:
Compared with the simple treatment, the use of Xuebijing injection in the treatment of severe pneumonia caused by Acinetobacter baumannii infection with a wide range of drug resistance has a significant clinical effect in the treatment of Bauman, it is worthy of promotion
2017 Vol. 23 (4): 662-664 [
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154
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675
Analysis of the Effect of Shugan Mingmu Decoction combined with Mecobalamin on Liver qi Stagnation in patients with Primary Intraocular pressure, Glaucoma Visual Acuity and CRP
CAI Xiaojun, ZHAO Xiaolong
DOI: 10.3969/j.issn.1006-6233.2017.04.043
Objective:
To study the impact analysis of Shugan Mingmu decoction combined with Mecobalamin on patients with liver qi stagnation primary open-angle glaucoma intraocular pressure,visual acuity and CRP.
Methods:
156 cases (274 eyes) of patients with stagnation of liver Qi POAG. admitted in our hospital from January 2015 to December 2016 were selected as objects. The patients were divided into observation group 78 cases (136 eyes) and control group 78 cases (138 eyes) according to the digital method. The two patients were treated with mecobalamin. The patients in the observation group were treated with Shugan Mingmu Decoction combined mecobalamin. The IOP, visual acuity, CRP level and adverse reactions were compared between the two groups before and after treatment for 3 months.
Results:
The cure rate of the observation group was 57.69%,the total effective rate was 94.87%, compared with the control group of 30.77% and 84.62% were significantly higher, the difference was statistically significant(P<0.05). After treatment, the IOP reduced value and visual acuity rise value of the observation group were significantly higher than those of the control group, the difference was statistically significant(P<0.05).After treatment,the levels of CRP in the observation group was significantly lower than control group,the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of allergies, anorexia, nausea, vomiting and diarrhea, as well as adverse events in the observation group (P > 0.05).
Conclusion:
Using Shugan Mingmu Decoction and Mecobalamin in treatment of liver qi stagnation POAG patients with better curative effect, also can effectively improve the intraocular pressure,visual acuity and the level of CRP, which is worthy of promotion
2017 Vol. 23 (4): 675-678 [
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105
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679
Study on the Effect of Scutellaria Decoction and the Changes of Serum IL-6 IL-8 and MVD and the Quality of Life in Patients with Gastric Cancer
WANG Jinling
DOI: 10.3969/j.issn.1006-6233.2017.04.044
Objective:
To study the effect of Huangqin decoction treatment in patients with gastric cancer and IL-8 on serum IL-6, MVD level.
Methods:
108 patients with gastric cancer admitted in our hospital from May 2014 to April 2016 were randomly divided into control group and observation group, 54 cases in each group. The patients in the control group were received simple DCF chemotherapy, and the observation group was treated with Scutellaria decoction based DCF chemotherapy. The curative effect, improve the quality of life and the incidence of bone marrow suppression of two groups patients were compared. The serum IL-6, IL-8 and MVD levels before and after treatment were compared.
Results:
The RR and DCR of the observation group were significantly higher than the control group (P<0.05), the observation group after treatment of the quality of life improvement rate (53.70%) was significantly higher than the control group (29.63%) (u=5.31,P=0.01); after treatment, the serum IL-6, IL-8, MVD levels of the observation group were significantly lower than the control group (P<0.01); the incidence of bone marrow suppression of the observation group was significantly lower than the control group (u=4.02,P=0.03).
Conclusion:
Scutellaria decoction can obviously improve the curative effect of gastric cancer, inhibit the inflammatory reaction, improve the quality of life, and can reduce the side effects of chemotherapy, it is worthy of clinical promotion
2017 Vol. 23 (4): 679-681 [
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106
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686
Clinical Observation of Ginseng Oral Ulcer Qinji Decoction in the Treatment of Radiotherapy
DU Haifeng, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.046
Objective:
To study the efficacy of Chinese medicine treatment of oral ulcer patients gargle after radiotherapy.
Methods:
96 patients with head and neck radiotherapy were randomly divided into control group, Chinese medicine group and compound group. The three groups in the first week after radiotherapy, the control group application of Kangfuxin Liquid oral gargle, traditional Chinese medicine group were treated with Salvia Decoction gargle, compound group were treated with Salvia decoction combined with Kangfuxin liquid.
Results:
After 6 weeks, the curative effect of traditional Chinese medicine group and compound group was better than that of control group (p<0.05).
Conclusion:
Salvia Decoction gargle can make oral ulcer and xerostomia significantly decreasing, and increase patient comfort and assist the completion of radiotherapy
2017 Vol. 23 (4): 686-688 [
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116
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689
The Application of Task-Based Learning Model in Medical English Teaching
HU Xiangdong, LI Qiang, ZHANG Xiaodong, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.047
Objective:
To investigate the application method and effect of task-based learning in medical English teaching.
Method:
On the basis of literature review, TBL was applied to medical English teaching, and experience was summarized.
Result:
We abided by five basic principles, such as real feasible task, learning by participating, combination of function and form, stimulating students' interest and the continuity of the task. Based on the peculiarities of clinical medical English teaching, TBL enriched the teaching forms, inspired the students' interest and motivation for autonomous learning, which was widely accepted by the students.
Conclusion:
TBL in medical English teaching is effective and worthy of popularization
2017 Vol. 23 (4): 689-690 [
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89
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691
Study on Satisfaction Index Model and Reliability and Validity Test of Outpatients
SHANG Rongyu, LIU Junyan, WANG Duan, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.048
Objective:
To systematically analyze the outpatient-satisfaction-related factors and their relationships and establish the exponential model of outpatient satisfaction which is suitable for the current medical environment in China and test its reliability and validity.
Method:
Foreign studies on outpatient satisfaction were analyzed through documentary method to establish a tentative outpatient satisfaction evaluation system draft consisting of three grades of indicators and to make a questionnaire. Purposeful sampling method was employed to find proper respondents and then face-to-face interviews were conducted. Delphin Method was used to consult the respondents for three rounds and
Results:
were analyzed. Result: Outpatient satisfaction index evaluation system consisting of five structure variables as hidden variables and four dimensions as dependent variables was established. The relationship between outpatient-satisfaction-related factors and outpatient satisfaction was uncovered and the reliability and validity of outpatient satisfaction questionnaire were tested.
Conclusion:
The exponential model of outpatient satisfaction contains core factors involved in outpatient satisfaction. The model has general applicability and comparability and reveals the problems of outpatient department actually and vividly. The adjusted outpatient satisfaction questionnaire is reliable and feasible and can be used as a promising evaluation tool for outpatient satisfaction
2017 Vol. 23 (4): 691-696 [
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104
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697
Analysis of Confirmation Laboratory Test Results of HIV in Langfang City in 2015
ZHANG Baoyan, GAO Feng, YONG Yunyun, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.049
Objective:
To analyze HIV confirmatory laboratory test results in Langfang City in 2015, to understand the city's screening laboratory testing and quality control, to understand the characteristics of the population and the prevalence of HIV infection in different populations, and provide evidence for AIDS prevention and control strategies.
Methods:
A total of 273 samples of positive samples were collected from the HIV/AIDS screening laboratory in Langfang City in 2015. The data of 273 HIV antibody checklist were recorded by Excel.Western blot test for the use of inspection samples tested, laboratory confirmation data for statistical analysis.
Results:
273 people were collected by the Langfang Municipal Center for Disease Control and Prevention confirmed AIDS laboratory test results positive for 159 people, 94 were negative and uncertain for 20 people. For 159 positive samples, 142 cases were male (89.31%, 159/273), 17 cases were female (10.69%, 17/159), the sex ratio is 8.35:1. The age of the patients was mainly 21-40 years (55.35%, 88/159), followed by 41-50 years of age in all of the patients (n = 23.90%, 38/159), in the case of the age of 50 years (n = 19.50%,) (n = 31, 31/159) (n = 88). The distribution of the population was mainly in 102 men (64.15%, 102/159).
Conclusion:
Strengthening HIV screening laboratories HIV antibody testing laboratory and quality control can increase health education and behavioral intervention for high-risk groups to curb the spread of AIDS
2017 Vol. 23 (4): 697-698 [
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156
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702
Analysis of Nursing Defects in Hemodialysis Patients in a Hospital and Countermeasures
CAO Hongmin, TIAN Bin, KANG Wei, et al
DOI: 10.3969/j.issn.1006-6233.2017.04.051
Objective:
To analyse hemodialysis nursing problems, and summarize the cause of problems and solutions.
Methods:
98 patients admitted with hemodialysis treatment in our hospital form October 2014 to May 2016 were selected as the research objects. The nursing defects were retrospectively analyzed for all the patients. Its influence factors were summarized in combination with the actual situation of patients, and finally to explore a set of effective measures to improve hemodialysis nursing service.
Results:
Of the 98 patients, the main nursing defects for the loss of blood disease, arteriovenous puncture failure cause subcutaneous large hematoma, parameter setting error, instrument using error, arteriovenous fistula way with the internal fistula arteriovenous connection error, the largest loss of hematic disease, arteriovenous fistula in the road and fistula arteriovenous end connection error, at least in the middle and the remaining three proportion was more close to; The causes of these defects mainly included the nurse poor judgment, risk awareness, to check my work does not reach the designated position, poor technology, inattention, which was caused by nursing staff errors of judgment the most number of cases.
Conclusion:
Hemodialysis nursing defects often occur, leading to many factors of nursing problems. The hospital must be the reason to develop effective measures to change this to provide a good therapeutic environment, avoid the occurrence of nursing defects
2017 Vol. 23 (4): 702-704 [
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