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2017 Vol. 23, No. 5
Published: 2017-05-20
705
The Clinical Effect Cognitive Function and Prognosis of Patients with Chronic Renal Failure Treated by Hybrid Blood Purification
ZHOU Meilan, HE Lijie
DOI: 10.3969/j.issn.1006-6233.2017.05.001
Objective:
To observe the clinical effect, cognitive function and prognosis of patients with chronic renal failure treated by hybrid blood purification.
Methods:
128 cases of elderly patients with chronic renal failure adapted blood purification treatment from July 2014 to July 2015 as the research object, according to the different dialysis, the patients divided into two groups, each group with 64 cases, control group only used dialytic treatments, while observation group used the type hybrid blood purification treatment, compared the clinical effect and prognosis of the two groups.
Results:
The levels of siderophilin, hemoglobin, serum albumin, serum prealbumin of observation group after treatment were higher than the control group (P < 0.05). The total score of cognitive function of observation group after treatment was better than that of control group (P < 0.05); The somatic pain, emotional functions, social functions, overall health score of observation group after treatment was better than that of control group (P < 0.05).
Conclusion:
Hybrid blood purification treatment can ameliorate the symptoms of malnutrition in elderly patients with chronic renal failure, improve their cognitive function, their quality of life and have good prognosis.
2017 Vol. 23 (5): 705-707 [
Abstract
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137
)
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708
The Effect on Intra-abdominal Pressure by Continuous Veno-venous Hemofiltration Combined with Hemoperfusion in Patients with Severe Sepsis
LUO Weixiong, ZHANG Yanfeng, LUO Weiwen
DOI: 10.3969/j.issn.1006-6233.2017.05.002
Objective:
To investigate the effect on intra-abdominal pressure by continuous veno-venous hemofiltration(CVVH) combined with hemoperfusion(HP) in patients with severe sepsis.
Methods:
60 cases of patients with severe sepsis were enrolled in the research from ICU of our hospital from December 2011 to August 2014 with the prospective study method. All of the patients were treated by anti-infection, restrictive liquid recovery, gastrointestinal decompression, enema catharsis, inhibition of gastric acid, sedation and analgesia, nutritional support and maintenance of electrolyte and acid-base balance. CVVH combined with HP were applied in this research for five days on the above basis of routine treatment. The changes of intra-abdominal pressure (IAP), C-reactive protein (CRP), procalcitonin(PCT), mean arterial pressure (MAP), lactic acid (Lac), serum creatinine (Scr), oxygenation index (PaO
2
/FiO
2
), acute physiology and chronic health evaluation Ⅱ (APACHE - Ⅱ score) and sepsis-related organ failure assessment (S0FA) were compared before treatment and after treatment in patients with 12h, 1d, 3d, 5d.
Results:
CVVH combined with HP treatment of 12h patients with PCT, Scr began to decline, compared with before treatment, the difference was statistically significant (P<0.05). IAP, CRP, PCT, Lac, Scr, APACHE Ⅱ score and SOFA score were all falling after 1d treatment. MAP and OI began to rise and the differences were statistically significant compared with before treatment. IAP, CRP, Lac, Scr, APACHE Ⅱ scores declined daily after treatment and declined to the lowest after 5d treatment. PCT and SOFA score reduced day by day after treatment and fell to the lowest after 3d treatment. They increased slightly in the fifth day. MAP and OI increased after treatment, the highest value reached 5D after treatment.
Conclusion:
CVVH with HP therapy can effectively reduce the internal pressure and improve the condition for patients with severe sepsis and intra-abdominal hypertension.
2017 Vol. 23 (5): 708-711 [
Abstract
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103
)
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712
The Effect of Escitalopram on the Expression of 5-HT DA INH and NE in Different Brain Regions of Patients with Depression
WAN Shu
DOI: 10.3969/j.issn.1006-6233.2017.05.003
Objective:
To investigate the expression of 5-HT, DA, INH and NE in patients with depression after escitalopram treatment, and to provide the basis for clinical application.
Methods:
50 cases of patients with depression admitted from June 2014 to January 2015 in our hospital were analyzed, using escitalopram to intervene; analysed live full brain, around the central, frontal, occipital, left and right around the left and right top, left temporal and other areas of the brain in 5-HT, DA, INH, NE induced analysis before and after treatment, patients with clinical treatment records.
Results:
The clinical effective rate was 92% after treatment with escitalopram; the 5-HT of the whole brain, right, right, right and right anterior temporal regions were significantly reduced, after treatment and the difference was statistically significant (P<0.05); The DA levels in the whole brain, right frontal, right central, right top, right anterior temporal area were significantly increased, and the difference was statistically significant (P<0.05); The INH level in the left frontal area was significantly lower (P<0.05); The left central part and right central NE levels were significantly lower (P<0.05); and the NE levels in the left and right occipital regions were significantly higher (P<0.05).
Conclusion:
After the treatment with escitalopram, the clinical effect of the patients with depression is good, and it can effectively correct the abnormal expression of 5-HT, DA, NE, and INH in each brain region.
2017 Vol. 23 (5): 712-715 [
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] (
93
)
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716
Annular Corneal Staining Score Model in Different Refractive Status in Juvenile Patients with Ametropia
WANG Donghua, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.004
Objective:
To analyze the circular corneal fluorescein staining scores in teenagers patients with refractive errors among different accommodation.
Methods:
166 teenagers patients with refractive errors were randomly selected, they were divided into myopia group (-0.50～-10.50D), hyperopia group (+0.50～+5.50D) and normal group, in 0min, 15min and 30min, using the circular corneal fluorescein staining scores to observe the fluorescein of the cornea.
Results:
With the inhance of the observation time, the accommodation time and range, the circular corneal fluorescein staining scores became more and more (P<0.05).
Conclusion:
With the changing of the accommodation time and range of teenager patients with refractive errors, the circular corneal fluorescein staining scores became more and more, the stability of teenagers refractive error patients'tear film descended.
2017 Vol. 23 (5): 716-718 [
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] (
108
)
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719
The Clinical Significance and Expression of Phosphoglycerate Mutase-1 in the Testis Tissues of Patients with Different Types of Prostatitis
HUANG Minyu, HUANG Qun, WU Jun, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.005
Objective:
To observe the phosphoglycerate mutase (PGAM1)-1 expression in testicular tissue of patients with different types of prostatitis, to analyze the clinical significance of detecting PGAM1 expression.
Methods:
Type I,II,III and IV prostatitis patients and healthy population of the testicular tissue specimens were collected. The level of PGAM1 expression was detected by immunohistochemical. The difference of PGAM1 expression in patients with different types of prostatitis was analyzed. The relationship between the expression of PGAM1 and the levels of follicle stimulating hormone, luteinizing hormone and testosterone was analyzed.
Results:
There was no significant difference in the expression of PGAM1 in the testis tissue of patients with typeⅠ(P>0.05). The expression of PGAM1 in testis tissues of patients with type II, III and IV prostatitis was significantly different from that in healthy people (P<0.05). There was no significant difference in the levels of follicle stimulating hormone, luteinizing hormone (LH) and T hormone (P>0.05) in patients with type Ⅰ prostatitis (PGAM1). However, there were significant differences in the levels of follicle stimulating hormone, luteinizing hormone and testosterone in patients with type PGAM1, type III and type IV prostatitis (P<0.05).
Conclusion:
In addition to the patients with type Ⅰ prostatitis, the expression of PGAM1 of patients with type II, III and IV prostatitis was lower. The abnormal expression of PGAM1 had an effect on spermatogenesis in patients with testicular tissue. Therefore, the detection of PGAM1 has a certain clinical value in the diagnosis of patients with prostatitis.
2017 Vol. 23 (5): 719-723 [
Abstract
] (
97
)
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724
Expression of Hepatocyte Growth Factor-1 in Human Glioma and Effect on Apoptosis of Glioma Cells
QUAN Junjie, QU Jianqiang, ZHOU Le, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.006
Objective:
To investigate the expression of hepatocyte growth factor -1 (PTP4A1) in glioma and effect on the apoptosis of glioma cells.
Methods:
Tissue protein in brain glioma and tumor adjacent tissues were extracted by total protein extraction kit; PTP4A1 protein expression were detected by western blot; siRNA-NC and PTP4A1-siRNA was transfected into the human glioma U251 cells of the logarithmic growth phase, and without any siRNA transfection as the control group, each group of cells transfected for 48h, expression of PTP4A1, Ki67, PCNA, Cleaved, Caspase3, β-catenin, CyclinD1, C-myc protein were detected by Western blot; cell proliferation was detected by CCK8 assay; cell apoptosis was detected by flow cytometry.
Results:
The expression of PTP4A1 protein in gliomas was significantly higher than that in the tumor adjacent tissues (P<0.01); the expression of PTP4A1 protein in siRNA-NC group and control group had no significant difference (P>0.05), expression of PTP4A1 protein in PTP4A1-siRNA group were significantly lower than the control group (P<0.01); compared with the control group and siRNA-NC group, the cell survival rate and the expression of Ki67, PCNA, β-catenin, CyclinD1, C-myc protein in PTP4A1-siRNA group were significantly decreased, cell apoptosis rate and expression of Cleaved Caspase3 protein was significantly increased (P<0.01).
Conclusion:
PTP4A1 is higher expression in glioma tissues. And silented PTP4A1 expression can inhibit the proliferation and induce apoptosis of human glioma U251 cells by down regulating the Wnt/β -catenin signaling pathway.
2017 Vol. 23 (5): 724-727 [
Abstract
] (
144
)
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728
The Effect of Internal and External Therapies in the Treatment of Children with Pneumonia and Effect on Procalcitonin hs-CRP and Immune Function
ZHANG Huali, WANG Chao, ZHANG Rui, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.007
Objective:
To find a new therapy for the treatment of pneumonia in children, to explore the clinical effect of combined internal and external treatment.
Methods:
200 cases of pneumonia patients were classified as the observation group and control group, each with 100 cases. The control group was treated with symptomatic treatment, the observation group based on the use of internal and external therapies in the control group. The treatment effect and the levels of hs-CRP, PCT, CD4+, CD4+/CD8+, Treg and CD4+CD25+ of two groups were observed.
Results:
After treatment, the curative effect of observation group was significantly better than the control group (P < 0.05). Before treatment, the hs-CRP level of observation group and control group was higher than that in healthy control group (P < 0.05), after treatment, there was no significant difference between the observation group patients and healthy control group, while the control group, the level of hs-CRP was slightly higher than that in the healthy control group (P < 0.05). Before treatment, the PCT level of observe group and control group was higher than that of the healthy control group (P < 0.05), after treatment, the observation group patients and healthy control group (P < 0.05), while the control group, the level of PCT was slightly higher than that in the healthy control group (P < 0.05). Before treatment, the levels of CD4+, CD4+/CD8+, Treg CD4+CD25+ in the observation group and the control group were lower than those in the healthy control group (P < 0.05). After treatment, there was no significant difference between the observation group and healthy control group, while the levels of CD4+CD25+, CD4+/CD8+ and Treg CD4+ in the control group were slightly higher than those in the healthy control group (P < 0.05).
Conclusion:
Combining internal and external therapy in the treatment of infantile pneumonia, the curative effect is significant, and can effectively improve children's hs-CRP, PCT, CD4 +, CD4 + / CD8 + and CD4 + CD25 + Treg levels.
2017 Vol. 23 (5): 728-731 [
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] (
154
)
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732
Anesthetic Effects of Dexmedetomidine Hydrochloride in Tonsillectomy and Influence on Postoperative Cognitive Function
LEI Hengfa, XIA Zhongyuan
DOI: 10.3969/j.issn.1006-6233.2017.05.008
Objective:
To analyze the anesthetic effect of dexmedetomidine hydrochloride in tonsillectomy and effect on postoperative cognitive function.
Methods:
150 patients admitted to our hospital were treated with tonsillectomy as the study object from September 2013 to December 2016. According to the anesthesia method, all the patients were divided into experimental group (application of dexmedetomidine hydrochloride Anesthesia)and the control group(intravenous injection of saline), each group with 75 cases. The postoperative disturbances, cognitive differences of two groups were compared.
Results:
The recovery time of the patients in the experimental group were significantly shorter than those in the control group (P <0.05). The postoperative agitation score and postoperative disturbance rate were significantly lower in the experimental group than in the control group. The difference of cognitive function between the two groups was statistically significant (P<0.05) at 4 hours postoperatively and 1 day after operation.
Conclusion:
The anesthetic effect of dexmedetomidine hydrochloride in tonsillectomy significantly is obviously. It can effectively improve the patient's postoperative cognitive function score.
2017 Vol. 23 (5): 732-734 [
Abstract
] (
132
)
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735
The Differential Diagnosis of Phyllodes Tumor of the Breast with Molybdenum Palladium and Ultrasonography
YAN Shuang
DOI: 10.3969/j.issn.1006-6233.2017.05.009
Objective:
To analyze 21 cases of breast phyllodes tumor of molybdenum and palladium and ultrasound and improve the diagnostic accuracy of the disease.
Methods:
The data of 21 preoperative color Doppler ultrasonography and X-ray molybdenum target confirmed by pathology were analyzed retrospectively. The density/echo, shape and size of the tumor were observed respectively.
Results:
The diagnosis of 21 cases of X-ray mammography was misdiagnosed as fibroma, 2 cases were misdiagnosed as breast cancer. The accuracy rate was about 76.19%. Ultrasound diagnosis of 21 cases of misdiagnosis of 4 cases of fibroma, misdiagnosed as breast cancer in the 3 cases, the accuracy rate of about 66.67%.
Conclusion:
The results showed that there's some characteristics in the diagnosis of breast phyllodes tumor, but there's no specificity. It should be distinguished from the fibroma and breast cancer in order to improve the diagnostic rate.
2017 Vol. 23 (5): 735-737 [
Abstract
] (
127
)
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738
Clinical Study on the Treatment of Hyperplasia of Mammary Glands with Biological Resonance Technology
JIANG Ziming, FENG Guangge, LI Yuanyuan, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.010
Objective:
To observe the efficacy of biological technique of channels and collaterals and traditional Chinese medicines (TCM) for soothing the liver, promoting blood circulation, eliminating swelling and removing stasis in treating liver-qi stagnation and phlegm stagnation type mammary gland hyperplasia and explore a treatment for the disease.
Methods:
All cases were collected from outpatient department of breast diseases in Yulin Hospital of Traditional Chinese Medicine from August 2016 to October 2016. A total of 120 patients with liver-qi stagnation and phlegm stagnation type mammary gland hyperplasia were enrolled in the study and were randomly divided into treatment group and control group according to the order of treatment, 60 cases in each group. Age, gender and duration of disease were compared between the two groups. The treatment group were treated with TCM screened by biological resonance technique and the control group were treated with the traditional Chinese medicine oral Rukuaixiao Granules. Both groups were treated for 1 month.
Results:
The total effective rate of treatment was higher in treatment group than the control group (85.00% vs 66.67%).
Conclusion:
TCM screened by biological technique of channels and collaterals are effective in the treatment of liver-qi stagnation and phlegm stagnation type mammary gland hyperplasia, without side effects, which is worthy of further study.
2017 Vol. 23 (5): 738-740 [
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] (
190
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741
Effects of Rumex Japonicus Houttextract on Transforming Growth Factor-β
1
and Receptors in Thrombocytopenic Purpura Mice
GAO Yang, JIANG Zujun
DOI: 10.3969/j.issn.1006-6233.2017.05.011
Objective:
To observe the effects of Rumex japonicus Houtt extract on transforming growth factor-β
1
and its receptors in thrombocytopenic purpura mice model.
Methods:
40 BALB/C mice were randomly divided into positive control group, model group, rumex japonicus houtt extract group and negative control group. All ITP mouse model were made by injected guinea pig-antimouse platelet serum (GP-APS) except negative control group. The expressions of TGF-β
1
and their receptors TGF-βR in the peripheral blood of mice were detected by the real-time PCR and Western Blot, and differences of their expression levels were analyzed.
Results:
The expression of TGF-β
1
in ITP model group was significantly higher than that in the negative control group (P<0.05), while the TGF-β mRNA and TGF-β protein expression in ITP model group were significantly lower than that in the negative control group (P<0.05). The expression of TGF-β
1
in rumex japonicus houtt extract group was significantly lower than that in the ITP model group (P<0.05), while the TGF-β mRNA and TGF-β protein expression in rumex japonicus houtt extract group were significantly higher than that in the ITP model group (P<0.05).
Conclusion:
Rumex japonicus houtt extract can regulate the immune function of ITP by in fluencing the expression of transforming growth factor-β
1
and its receptors.
2017 Vol. 23 (5): 741-744 [
Abstract
] (
117
)
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745
Effect of Different Incisions on Preexisting Corneal Astigmatism During Phacoemulsification
GUO Litao, ZHANG Tiemin, TAN Xiaobo, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.012
Objective:
To compare the effect of different incisions on preexisting corneal astigmatism during phacoemulsification.
Methods:
According to the results of corneal topography, corneal astigmatism between 1.0 D to 2.0 D, 47 patients (59 eyes) were divided into 2 groups. Different incisions for cataract surgery were made for each group. Group A (30 eyes): surgical incision for conventional 11:00 3.0mm transparent corneal incision; Group B (29 eyes): the incision was the clear corneal incision on the steepest corneal meridian. After surgery, the corneal topography was observed. The visual acuity, corneal astigmatism, astigmatism and astigmatism of the patients were observed at 1 week, 1 month, 3 months after operation.
Results:
The visual acuity of each group was significantly improved after operation. There was no significant difference for group A astigmatism before and after operation (p>0.05). Compared with group A, the astigmatism of group B was significantly reduced, and the difference was statistically significant (p<0.05). There was no significant difference between group A and group B at each time point in the axial ratio of astigmatism (p>0.05).
Conclusion:
The incisions on the steepest meridian can correct the midrange preexisting corneal astigmatism.
2017 Vol. 23 (5): 745-747 [
Abstract
] (
110
)
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748
The Value of Color Doppler Ultrasonography in the Detection of Fetal Posterior Fossa Structure in 11-13+6 Gestation Weeks
ZHANG Boyun, YAN Rui, LIU Xin, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.013
Objective:
To study the value of color doppler ultrasound in testing the structure of fetus posterior cranial-fossa during 11-13
+6
weeks pregnancy.
Methods:
The women of 11-13
+6
-weeks pregnant diagnosed monocyesis and accepted nuchal translucency (NT) examination were observed in this article in our hospital from February 2014 to February 2016. There were 502 fetuses in the normal group, 3 Dandy-Walker syndrome cases were belonged to the control group. The basic information of two groups, including the women's age, gestational age, height, weight, incest, childbearing history were recorded and analyzed. Using color doppler ultrasound to measure the fetal crown-rump length (CRL) and NT value. From scanning images of posterior cranial-fossa, including median sagittal section and premenstrual halid-e cerebellum transverse section, brain stem (BS) diameter, cistern magna (CM) diameter and the distance from brain stem to occipital bone (BSOB) were measured.
Results:
On the basic information, such as gestational age, height, weight and so on, there have no sig-nificant difference between the normal group and Dandy-Walker syndrome cases (P>0.05), but the CRL of Dandy-Walker syndrome fetus was shorter than the normal (P<0.05), while NT value was higher than the normal (P<0.05). Moreover, in the control group, the BS and CM were decreased, however BSOB was increased (P<0.05).
Conclusion:
It's different about the posteri-or cranial-fossa between Dandy-Walker syndrome fetus and the normal, including BS, CM and BSOB. It proves that color doppler ultrasoundcan be used to test the structure of fetus posterior cranial-fossa during 11-13
+6
weeks' pregnancy, and screen abnormal fetus.
2017 Vol. 23 (5): 748-751 [
Abstract
] (
153
)
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752
Analysis of the Efficacy and Safety of Laparoscopic Versus open Appendectomy
ZHENG Xiuyu
DOI: 10.3969/j.issn.1006-6233.2017.05.014
Objective:
To investigate the efficacy and safety of laparoscopic appendectomy in the treatment of acute appendicitis.
Method:
Retrospective analysis of 80 patients with acute appendicitis accepted surgical treatment in our hospital from June 2014 to June 2015. Randomly divided into observation group (n=40) and control group (n=40). The observation group was received laparoscopic appendectom, the control group was treated with traditional open appendectomy. Then the operation and postoperative recovery status of the two groups of patients were compared.
Result:
The operation time and blood loss of the observation group were less than that of the control group (P < 0.05), postoperative exhaust time, eating time and hospitalization time were shorter than the control group (P < 0.05),and the difference was statistically significant. Wound infection and intestinal obstruction were less than that of the control group (P > 0.05), But the differences were not statistically significant.
Conclusion:
Laparoscopic appendectomy has the advantages of short operation time, less blood loss, good cosmetic results, and rapid postoperative recovery. It is a safe and feasible operative model, worthy of widespread implementation at all levels of the hospital.
2017 Vol. 23 (5): 752-755 [
Abstract
] (
122
)
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756
Analysis of Clinical and Pathological Features of Gastric Polyps and Colorectal Polyps
ZHU Shu
DOI: 10.3969/j.issn.1006-6233.2017.05.015
Objective:
To explore the clinical and pathological characteristics of gastric polyps and colorectal polyps.
Method:
The clinical data and pathological data of 63 patients with gastric polyps and 89 patients with colorectal polyps were collected and diagnosed by endoscopy center from September 2010 to October 2015. The age, sex, polyp detection rate, polyp size, number, location and pathological types were compared and analyzed.
Results:
The detection rate of gastric polyps (10.12%) was lower than that of colorectal polyps (16.96%). The detection rate of gastric polyps (4.46%) and the detection rate of colorectal polyps (8.21%) were less than The detection rate of colorectal polyps was higher than that of gastric polyps (5.71%, 8.75%), the difference was statistically significant (P <0.05) (12.0%) was higher than that of male (8.2%). The detection rate of colorectal polyp was 23.9% higher than that of female (11.0%)(P<0.05). Study of the size of the two polyps found that single gastric polyps more than single large intestinal polyps. The difference of the detection rate of inflammatory, proliferative and adenomatous polyps was statistically significant (P <0.05).
Conclusion:
The detection rate of gastric polyp was lower than that of colorectal polyp. The older the patients, the higher the detection rate of the two groups of older age groups were higher than the average age group, suggesting that with the increase of age, polyp detection rate the higher. Gastric polyps are common in female patients, and colorectal polyps are common in male patients. Pathological types of gastric polyps inflammatory polyps common, colonic polyps pathological types of tumor polyps are more common midline, analysis shows that the rate of colorectal polyps higher than the gastric polyps.
2017 Vol. 23 (5): 756-759 [
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] (
129
)
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760
Clinical Observation on the application of mixed Solution with Lidocaine and Nitroglycerin in Radial Artery Puncture
WANG Kun, CHANG Xin, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.016
Objective:
To explore the efficacy and safety of subcutaneous injection of lidocaine-nitroglycerin mixed solution to relieve radial artery spasm and improve the success rate of puncture.
Method:
A total of 214 patients with radial artery spasm during the course of puncture, from May 2013 to May 2015 in the cardiology of Beijing Military General Hospital, were randomly divided into experimental group and control group. The patients in the experimental group were given 1% lidocaine 1.5ml + nitroglycerin injection 0.5ml (2.5mg) mixed solution subcutaneous injection, and the patients in the control group were given 1% lidocaine injection 2ml subcutaneous injection. Record the changes of radial artery pulsation、blood pressure and heart rate before and after treatment.
Results:
There was no significant difference in age, sex, hypertension, myocardial infarction,diabetes mellitus,smoking,LVEF,serum creatinine and high sensitivity C-reactive protein between the two groups (P<0.05). The time of puncture was 5.21 ±1.119 min in the experimental group and 8.32±1.506 min in the control group. The puncture time of the experimental group was significantly lower than that of the control group (P = 0.000). The number of puncture was 4.33±1.014 in the experimental group and 6.29±1.324 in the control group. The difference was statistically significant (P = 0.000). The time of recovery pulsation of radial artery was 1.79±0.399 min in the experimental group and 3.36±0.629 min in the control group. The time of recovery pulsation of radial artery in the experimental group was significantly shorter than that in the control group. The difference was statistically significant (P = 0.000). (5) The success rate of puncture was 94.44% in the experimental group and 81.13% in the control group. The difference was statistically significant (P = 0.003). Before and after treatment, there were no significant change in blood pressure, headache, new arrhythmia and other adverse reactions of the two groups.
Conclusion:
The subcutaneous injection of 1% lidocaine 1.5ml+ 0.5ml nitroglycerin (2.5mg) mixed solution can effectively improve the radial artery spasm, improve the success rate of puncture, reduce the number of puncture, and shorten the time of puncture, with no obvious adverse reaction. Which is safe and effective, worthy of recommendation to use.
2017 Vol. 23 (5): 760-763 [
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126
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764
Analysis of Clinical Risk Factors of Placental Abruption during Pregnancy
LIU Jiuying, CAI Xiaonan, CAO Ming
DOI: 10.3969/j.issn.1006-6233.2017.05.017
Objective:
To investigate the clinical risk factors of PA in 167 cases of placental abruption (PA).
Methods:
Clinical data of 167 cases with placental abruption were retrospectively reviewed in Wuhan Children's Hospital from Jan.2007 to Dec. 2012. The data of PA pregnant women's age, residence, parity, twin or multiple pregnancy, prenatal vaginal bleeding, rupture of membranes, blood pressure, time of activity, there is no trauma, umbilical cord, oxytocin, chronic cough and constipation during pregnancy, placental abruption type were analyzed retrospectively.
Results:
The incidence of placental abruption was 0.56% including emergency patients accounting for 82.04%.105 cases had the main predisposing factors(62.87% ), mainly including hypertensive disorders of pregnancy, premature rupture of fetal membranes, with oxytocin and traumatic factors.
Conclusion:
Pay more attention to prenatal care, pregnant women with high risk factors of PA, once the occurrence of PA, as soon as possible diagnosis, active treatment, improve maternal outcome.
2017 Vol. 23 (5): 764-766 [
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101
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767
Cannabidiol Can Inhibit Inflammation in a Mouse Model of Spinal Cord Injury
LI Cuicui, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.018
Objective:
To investigate the inhibition of inflammation by cannabidiol in a mouse model of spinal cord injury and study its mechanism.
Methords:
24 male C57Bl/6 mice were randomized into 3 groups: sham-operation group, control group and medication group. We established an spinal cord injury model by clip method, the mice in sham-operate group and control group were administered with a mixture of 1% of tween 80 and sterile saline (0.25mL/10g) and medication group were treated with cannabidiol (30mg/kg ; was dissolved in a mixture of 1% of Tween 80 and sterile saline (1.2mg/mL)) by intraperitioneal injection at 1h、12h、24h、36h、48h、60h after operation.72h after operation , BMS test was used to evaluate the neurological score, the expression levels of HMGB1 and TNF-αin spinal cord tissue were assayed by ELISA.
Rsults:
The BMS test showed that medication group had a higher score than the control group(P<0.05). The expression levels of HMGB1 and TNF-α in medication group were significant reduced as comparison with control group P<0.05), but significant increased than the sham-operation group(P<0.05).
Conclusion:
Cannabidiol can inhibit inflammation in a mouse model of spinal cord injury via inhibiting the expression of HMGB1.
2017 Vol. 23 (5): 767-769 [
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770
Clinical efficacy study of different surgical pathways in the treatmentof non - invasive fungal maxillary Efficacy study
LLI Xiaofeng, CHEN Yinzhong, WANG Guangming, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.019
Objective:
To investigate the clinical effects of different surgical methods on non-invasive fungal maxillary sinusitis, and then to guide the surgical operation.
Methods:
Sixty - six patients with non - invasive fungal maxillary sinusitis underwent endoscopic sinus surgery (ESS) were divided into three groups: 25 cases were treated with endoscopic maxillary sinus windowing (EMSS) ,simple endoscopic maxillary sinus open - (EMIF group), 22 cases of nasal endoscopy combined with inferior meatus pathways group (EMIF group) , opening combined with glottic sulcus approach group (ESSL group) in 19 cases under nasal endoscopic nasal .The clinical symptoms, the situation of nasal cavity and paranasal sinus lesions were compared between the three groups.
Results:
The therapeutic effect was evaluated by the standard of Haikou. The effective rates of EMSS, EMIF and ESSL were 80.0%, 94.7% and 100%, respectively. Compared with EMIF group and ESSL group, EMSS had significant difference (P<0.05). There was no significant difference between EMIF group and ESSL group (P>0.05). There were no significant differences in the VAS score, Lund-Kennedy endoscopic score and Lund-Mackay CT score between the three groups before operation (P>0.05). There were significant differences between EMSS group and EMIF group and ESSL group before and after operation (P <0.05). There were significant differences between EMSS group and EMIF group and ESSL group after operation (P<0.05) .There was no significant difference between EMIF group and ESSL group (P> 0.05). The VAS score, Lund-Kennedy endoscopic score and Lund-Mackay CT score were highest in the EMSS group at 6 months postoperatively.
Conclusions:
The combined approach has better therapeutic effect on non-invasive fungal maxillary sinusitis than EMIF and ESSL. However, the effect of EMIF and ESSL is not different. However, Trauma of the inferior meatus window is less, less blood and more convenient operation.It is an ideal method In clinical treatment of Non-invasive fungal maxillary sinusitis and worthy of promotion.
2017 Vol. 23 (5): 770-772 [
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109
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773
Observation of Clinical Efficacy in Patients with Coronary Artery Bypass Grafting Operation
LEI Bai, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.020
Objective:
To investigate the relationship between the fatality rate in patients with coronary artery bypass grafting and influences factors and evaluate the clinical efficacy of coronary artery bypass surgery and long-term follow-up.
Methods:
275 patients were telephoned follow-up, who were conducted the coronary artery bypass grafting in department of cardiac surgery, The Second Hospital of Hebei Medical University from Jan 2006 to Dec 2010. The patients with postoperative deaths, complications, and analysis the correlation between them were recorded to evaluate the clinical efficacy in patients with coronary artery bypass grafting operation.
Results:
In the actual follow-up of 275 cases, the death patients in perioperative and postoperative patients were 16 and the fatality rate was 5.92%. The complications were less and the higher fatality rate was in patients with several severe basic diseases, such as diabetes, hypertension and heart failure.
Conclusion:
The coronary artery bypass grafting has a better long curative effect in patients and the more significant treatment upon patients without basic diseases. The present study suggests that the coronary artery bypass grafting is one of the effective means in treatment of coronary heart disease.
2017 Vol. 23 (5): 773-775 [
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127
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776
Analysis of the Efficacy of Percutaneous Endoscopic Discectomy for Lumbar Intervertebral Disc Herniation
YANG Bo, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.021
Objective:
To discuss the curative effect analysis of transforaminal endoscopic discectomy typing method on the lumbar disc herniations.
Methods:
128 patients underwent percutaneous transforaminal endoscopic surgery of lumbar disc herniation patients with intervertebral foramen in diagnosing type, was divided into 4 types: compression type, scar, calcification type, lateral recess stenosis type; and the visual analogue score (visual analog, scale, VAS), oswestry disability index (Oswestry disability index ODI, Japan), department of orthopedics (Japanese Orthopaedic Association evaluation scores of Association Scores, JOA) and macNab standard to assess the efficacy of surgery.
Results:
The average (10.5 + 3.7) months of follow-up, the patients with low back pain VAS score and ODI score were significantly lower than that before operation, JOA was significantly higher than that before operation, MacNab rated excellent rate of 95.31%, VAS, ODI and JOA had significant difference (P<0.05).
Conclusion:
Percutaneous transforaminal endoscopic surgery for lumbar disc herniation are significantly different efficacy of transforaminal endoscopic, rational use of the classification can make the surgery greatly alleviate symptoms, improve curative effect, reduce the recurrence rate.
2017 Vol. 23 (5): 776-779 [
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147
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780
Risk factors of children’s refractory mycoplasma pneumoniae pneumonia
LIU Xinfeng ZHAO Zhimiao ZHANG Zhongping
DOI: 10.3969/j.issn.1006-6233.2017.05.022
Objective:
To study the risk factors of children’s refractory mycoplasma pneumoniae pneumonia(RMPP).
Methods:
The clinical data of 343 cases of mycoplasma pneumoniae pneumonia(MPP) from June 2012 to June 2013 were retrospective analyzed. The risk factors of RMPP were investigated using univariate analysis and multivariate logistic regression analysis.
Result:
Univariate analysis showed that five factors were related with RMPP:fever lasting more then seven days(OR＝1.710,P＜0.05), complication diseases(OR＝36.458,P＜0.01),Chest CT (more than two-thirds of lung lobe) (OR＝1.796,P＜0.05)、CRP≥40mg/l(OR＝18.935,P＜0.01)、MP-IgM≥1:1280(OR＝20.494,P＜0.01)。Multivariate logistic regression showed that complication diseases(OR＝57.906,P＜0.01)、CRP≥40mg/l(OR＝28.877,P＜0.01)、MP-IgM≥1:1280(OR＝14.642,P＜0.01)were the independent risk factors for RMPP.
Conclusions:
RMPP is caused by many factors,among which, complication diseases、CRP≥40mg/l、MP-IgM≥1:1280 are the independent risk factors.
2017 Vol. 23 (5): 780-782 [
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144
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848
Study on the Effect of Tongjingshu Decoction Combined with Conventional Acupuncture Treatment of Dong's Extra-point on the Symptom Score and Prognosis for Dysmenorrheal
SUN Xiufeng
DOI: 10.3969/j.issn.1006-6233.2017.05.045
Objective:
To observe the effect of Tongjingshu Decoction (with alleviating effect for dysmenorrheal) combined with conventional acupuncture treatment of Dong's extra-point on the improvement of symptom and prognosis for dysmenorrheal.
Methods:
The clinical data of 110 patients with dysmenorrheal treated in our hospital between January 2013 and December 2014 were reviewed, which according to the different treatments given, were divided into two groups, each with 55 cases. The control group underwent Yueyueshu Granule for treatment, whereas the study group was given Tongjingshu Decoction combined with conventional acupuncture treatment of Dong' s extra-point for treatment. The curative effect and the prognosis of the two groups of patients were observed and compared.
Results:
The effective rate of the treatment in the study group was higher than that in the control group, yet the recurrence rate in the former group was lower than that in the control group (P<0.05). Pain score in both groups after treatment was significantly lower than that before treatment, and improvement in the study group was more obvious (P<0.05).
Conclusion:
Tongjingshu Decoction combined with conventional acupuncture treatment of Dong's extra-point is of positive effect on the improvement of symptoms and prognosis for the treatment of dysmenorrheal, with higher efficacy, which is therefore worthwhile to be put into promotion and application.
2017 Vol. 23 (5): 848-851 [
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120
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852
Clinical Observation on the Treatment of Chronic Pelvic Inflammatory Disease with the Method of Invigorating Qi and Invigorating the Body High Enema Combined with Acupotomy
YANG Xiaomei
DOI: 10.3969/j.issn.1006-6233.2017.05.046
Objective:
To investigate the therapeutic effect of the treatment of chronic pelvic inflammatory disease with the method of Invigorating Qi and invigorating the body and combining with acupotomy in the treatment of chronic pelvic inflammatory disease.
Method:
75 cases of patients with chronic pelvic inflammatory disease were treated by invigorating Qi high enema, and compared with the needle knife therapy. According to different clinical manifestations of pelvic inflammation in 145 patients with this disease in different age patients; while the patients were randomly divided into experimental group (75 cases) and control group (70 cases), the control group received needle knife therapy; the experimental group was treated with Chinese herbal decoction treatment on the basis of the control group, the use of high position enema in the treatment, after 2 courses of treatment, evaluation of curative effect.
Result:
Gao Wei Guan's bowel combines needle knife rule of law to treat a chamber to blaze always efficiently for 92%.
Conclusion:
Gao Wei Guan's bowel combines needle knife the rule of law treat burning economy of a chamber, convenient, effective, worth clinical expansion.
2017 Vol. 23 (5): 852-853 [
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96
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854
Cause Analysis and Nursing Countermeasures of Complications of Tracheotomy in patients with Severe Craniocerebral Injury
LI Shuwei, TIAN Xiufen, YIN Xiuling, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.047
Objective:
To analyze the causes of complications of tracheotomy in patients with severe craniocerebral injury, and to explore the corresponding nursing measures.
Methods:
The clinical data of 106 patients with severe craniocerebral injury admitted in our hospital from January 2012 to March 2016 were analyzed and the causes and nursing measures of patients with complications were summarized.
Results:
In this group of patients, there were 42 cases of postoperative pulmonary infection patients. And the incidence rate was 40.6%. The analysis of severe craniocerebral injury after tracheotomy showed coma time > 1 weeks, mechanical ventilation and 10d and aspiration was the main factor of pulmonary infection.
Conclusion:
Severe craniocerebral injury patients with trachea cut sputum suction complications, and postoperative clinical nursing work should be strengthened, in order to prevent and reduce complications, promote patients recover
2017 Vol. 23 (5): 854-855 [
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148
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856
Analysis of the Effect of Quality Control Circle on Endoscopic Thyroid Pre-operation Visit
QIU Lifei, LIU Shumin, ZHAO Guojun
DOI: 10.3969/j.issn.1006-6233.2017.05.048
Objective:
To improve the satisfaction rate of patients with thyroid surgery using the quality control circle (QCC) to the preoperative visit of thyroid surgery.
Methods:
According to the voluntary participation and flexible principle, our "Love QCC" consists of 6 members in our department, and established the theme "to improve the patient satisfaction rate of endoscopic thyroid pre-operation visit", and carried on the statistical analysis, using fish bone diagram. Then we make corrective measures to compare the patient satisfaction rate of the endoscopic thyroid operation and give continuous quality improvement. The satisfaction rates of patients with thyroid surgery before and after the quality control circle were compared.
Results:
After QCC activities, the complete patient satisfaction rate of endoscopic thyroid has risen from 85 %to 95%, above 93% of the target value. By the comparison of the result before and after the QCC activity, the results was statistically significant, χ
2
=4.4.
Conclusion:
The QCC activities could improve the patient satisfaction rate of endoscopic thyroid operation, improve the professional ability of nursing staff, and nursing quality and group cooperation have been continuous improved.
2017 Vol. 23 (5): 856-858 [
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136
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859
Application of Rehabilitation Nursing in the treatment of Knee Osteoarthritis after Arthroscopic Surgery
DU Ling
DOI: 10.3969/j.issn.1006-6233.2017.05.049
Objective:
To study the application effect of rehabilitation nursing in postoperative care of arthroscopic treatment of knee osteoarthritis (KOA).
Methods:
A total of 86 cases of KOA patients who underwent arthroscopic treatment in our hospital from January 2012 to June 2016 were divided into rehabilitation nursing group (n=43) and routine treatment group (n=43). Patients in routine treatment group were performed routine nursing, based on this, patients in rehabilitation nursing group were performed rehabilitation nursing. The knee-joint flexion degree, pain score and Tegner motor score before operation and at discharge, and the Lequesne score, the levels of tumor necrosis factor α (TNF-α), interleukin 1β(IL-1β) and matrix metalloproteinase-13(MMP-13) in synovial fluid and postoperative complications before operation and 6 months after discharge of patients in the two groups were compared.
Results:
On discharge, the knee-joint flexion degree in rehabilitation nursing group was greater than in routine treatment group, the pain score was smaller than in routine treatment group, the incidence rate of Tegner motor of Grade 1~2 was lower than in routine treatment group, the incidence rate of Tegner motor of Grade 3~4 was higher than in routine treatment group, and the difference was statistically significant (p < 0.05). At 6 months after discharge, the Lequesne score and levels of TNF-α, IL-1β and MMP-13 in the synovial fluid were lower than in routine treatment group, and the difference was statistically significant (p < 0.05). The good rate of rehabilitation nursing group (95.35%) was significantly higher than that of routine treatment group (65.17%), and the difference was statistically significant (p < 0.05). No significant adverse reaction was found during nursing in the two groups.
Conclusion:
The application of rehabilitation nursing in postoperative care of arthroscopic treatment of KOA can effectively promote the recovery of joint function, reduce inflammatory response and have significant curative effect, which is safe and reliable.
2017 Vol. 23 (5): 859-862 [
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870
Comparison of the Difference between VCT Confirmed and Other Confirmed HIV/AIDS Cases Infected by Sexual Transmission of Tangshan
WEI Xueqian, MAO Lichao, ZHANG Zhikun, et al
DOI: 10.3969/j.issn.1006-6233.2017.05.053
Objective:
To compare the difference between voluntary counseling and testing (VCT) pathway confirmed and other sources confirmed HIV/AIDS cases infected by sexual transmission, in order to clarify the characteristic of sexual transmission group that accepted VCT.
Methods:
Collected the information of HIV/AIDS cases infected by sexual transmission who were reported by Tangshan from 2011 to 2015.The information included cases' basic characteristics, route of transmission and CD4
+
test. Compared the differences between the VCT diagnosed cases and other diagnosed cases.
Results:
There were 515 HIV/AIDS cases infected by sexual transmission, including 186 cases were confirmed through VCT and 329 cases were confirmed through other ways. The age in cases diagnosed by VCT (29.37±9.89) was younger than the cases diagnosed by other ways (35.87±13.43). VCT diagnosed cases had a higher proportions of men (95.70%), unmarried (64.52%), with collage degree or above (40.86%), and cases in the service industry (29.03%). More MSM HIV/AIDS cases were found by VCT (83.87%). The first CD4
+
T lymphocyte counts were statistically higher in VCT diagnosed cases (422.62±277.71).
Conclusion:
VCT would be accepted more easily among the HIV/AIDS infected by sexual transmission of unmarried, younger age, with collage degree or above, and cases in the service industry.
2017 Vol. 23 (5): 870-872 [
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137
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873
Prevalence and Risk Factors of Mammary Gland Hyperplasia Among Female Workers in a Hospital in Qinhuangdao
WANG Jingshi, LI Yanguo
DOI: 10.3969/j.issn.1006-6233.2017.05.054
Objective:
To explore the effective method of reducing the incidence of mammary hyperplasia in female workers in a hospital of Qinhuangdao city by analyzing the situation and risk factors of breast hyperplasia.
Method:
1154 female workers who took part in physical examination in the hospital in 2015 were selected as the research object. Breast survey was made by B ultrasonography for all the objects. According to the classification of normal and breast hyperplasia, statistical analysis of prevalence and risk factors of hyperplasia of mammary glands in accordance with the six aspects of work, section categories and different degree, different age, different titles, such as monthly night shift.
Result:
A total of 1154 women were included in the study, the incidence of breast hyperplasia was 44.45%. According to the distinction between jobs, the highest rate of breast hyperplasia, sick doctor was 50.31%, followed by nurses, the prevalence rate was 46.69%, the prevalence rate of the work of breast hyperplasia compared with statistical significance (χ
2
=43.770, P<0.05); According to the department, the highest rate in the emergency department of breast hyperplasia was 85.42%, followed by surgery, the prevalence rate was 48.69%, the prevalence rate of the breast hyperplasia compared with statistical significance (χ
2
=44.390, P<0.05); According to the different age, the prevalence rate of 31 ~ 40 years old was 65.44%, followed by the age of the patients from the age of 41 to the age of 41.89%, and the prevalence of breast hyperplasia in different age groups was statistically significant (χ
2
=80.570, P<0.05); According to the comparison of monthly night shift, night shift in >6 days breast hyperplasia and the highest prevalence rate was 80%, 4 ~ 6 days group of breast hyperplasia prevalence rate was 68.35%, the prevalence rate of different monthly shift compared to the array of breast hyperplasia. The difference was statistically significant (χ
2
=254.760, P<0.05); According to the title, the prevalence rate of the intermediate grade was 55.36%, and the prevalence rate of primary disease was about 22.22%. There was a significant difference in the incidence of hyperplasia of mammary glands between different titles (χ
2
=80.570, P<0.05).
Conclusion:
Jobs, Department category, age, monthly night shift, the title is the risk factors of hospital workers of breast hyperplasia, must according to the related risk factors of prevention to reduce health care system of female workers in prevalence rate of breast hyperplasia.
2017 Vol. 23 (5): 873-877 [
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150
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878
Analysis on the Current Situation and Influencing Factors of Health Records of Urban Residents in Chengde
ZHANG Yi
DOI: 10.3969/j.issn.1006-6233.2017.05.055
Objective:
To study the current situation and influencing factors of health records of urban residents in Chengde city.
Methods:
A total of 800 households in Chengde city were selected by multi-stage stratified cluster sampling, to investigate the establishment of health records, and to investigate the influencing factors by single factor and multi factor Logistic regression analysis.
Results:
In the 800 subjects, 685 (85.63%) had established health records, 115 (14.38%) did not establish health records. The factors that affected the health records of residents in Chengde city were age, household income, whether to enjoy financial assistance, and whether they were satisfied with health education, and whether to participate in the training of health institutions and other factors, especially whether or not to accept financial assistance, the satisfaction of health education and whether to participate in the training of health institutions had a greater impact.
Conclusion:
The establishment of health records still need government support, increase to establish the significance of archives propaganda, establish corresponding supervision and accountability mechanisms, improve the awareness of residents to establish archives, as a basis to improve the health level and health quality and lay a solid.
2017 Vol. 23 (5): 878-880 [
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109
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