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| Related Factors Analysis of Pancreatitis Orhyperamylasemia after ERCP |
| FAN Xiuping, HUANG Xiaoli, LI Xiaohui, et al |
| The First Affiliated Hospital of Chengdu Medical College, Sichuan Chengdu 610500, China |
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Abstract Objective: To observe the risk factors of pancreatitis and hyperamylasemia after endoscopic retrograde cholangiopancreatography (ERCP). Methods: The clinical data of 196 patients undergoing ERCP in our hospital from March 2017 to March 2018 were retrospectively analyzed. According to the occurrence of post-ERCP pancreatitis (PEP) and post-ERCP hyperamylasemia (PEPH), the patients were divided into study group (concurrent with PEP or PEPH, n=41) and control group (not concurrent with PEP or PEPH, n=155). The differences in clinical data were compared between the two groups. Logistic regression analysis was used to analyze the risk factors affecting the occurrence of PEP or PEPH. Results: The proportions of patients with pancreatitis history, drinking history, common bile duct stricture, duodenal papillary diverticulum and intubation difficulties in study group were higher than those in control group, and the levels of blood WBC, PLT and Alb and ERCP operation time and frequency of entering pancreiatic duct in study group were greater than those in control group (P<0.05). Logistics regression analysis showed that the pancreatitis history, common bile duct stricture, duodenal papillary diverticulum, intubation difficulty and frequent pancreatic duct entering were independent risk factors for PEP or PEPH (P<0.05). Conclusions: The pancreatitis history, common bile duct stricture, duodenal papillary diverticulum, intubation difficulty and frequent pancreatic duct entering will increase the risk of PEP and PEPH in patients with ERCP. The emphasis should be placed on the above situation and timely intervention should be given to help to improve the prognosis of patients.
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2019, Vol. 25 
