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| Curative Effect of Pterygium Excision Combined with Limbal Stem Cell Transplantation in Elderly Patients with Pterygium and the Effect on Tear Film Function |
| MA Liming, LI Bo |
| West China Guang'an Hospital, Sichuan University, Sichuan Huaxi 638000, China |
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Abstract Objective: To analyze the curative effect of pterygium excision combined with limbal stem cell transplantation in elderly patients with pterygium and the effect on tear film function. Methods: 84 elderly patients with pterygium were divided into the observation group (n=42, a total of 56 diseased eyes treated by pterygium excision combined with limbal stem cell transplantation) and the control group (n=42, a total of 54 diseased eyes treated by pterygium excision alone) by simple random number table method. The tear film stability , tear film function, uncorrected visual acuity (UCVA), corneal astigmatism degree (CAD), complications and recurrence rate were observed. Results: SIT and BUT decreased in both groups at 4 weeks after treatment, while CFS and OSDI scores increased (P<0.05). SIT, BUT, CFS and OSDI scores returned to the levels before treatment at 8 weeks after treatment (P>0.05). The above indexes in the observation group were superior to those in the control group at 4 weeks after treatment (P<0.01). There was a significant difference in the grade of tear film function between the two groups at 12 weeks after treatment (P<0.05), and the ratio of grade I～II in observation group was higher than that in the control group (P<0.05). The UCVA increased and the CAD decreased at 4 weeks, 8 weeks and 12 weeks after treatment (P<0.05), but there was no significant difference between the two groups (P>0.05). The incidence of complications and recurrence rate in the observation group were lower than those in the control group at 12 weeks after treatment (P<0.05). Conclusion: The curative effect of pterygium excision combined with limbal stem cell transplantation is good in elderly patients with pterygium. The combined treatment is beneficial to recovery of tear film function and visual acuity, and it can reduce complications and recurrence rate.
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2019, Vol. 25 
