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| Comparison on the Therapeutic Effect of Interventional Embolization of Intracranial Aneurysms at Different Times |
| HUANG Yongwang, et al |
| The Affiliated Hospital of Guilin Medical College, Guangxi Guilin 541001, China |
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Abstract Objective: To compare the therapeutic effects of interventional embolization of intracranial aneurysms at different times. Methods: The clinical data of 102 patients with intracranial aneurysms treated by interventional embolization in our hospital from March 2015 to March 2018 were retrospectively analyzed. According to the timing of interventional therapy, group A (54 cases) had the onset time less than 72 hours, and group B (48 cases) had the onset time longer than 72 hours. The scores of embolism degree, modified Rankin scale, neurologic function impairment scale and MOS 36-items short form-health survey (SF-36) were compared between the two groups. Results: Compared with group B (58.33%), the complete embolization rate in group A (81.48%) was significantly increased (P< 0.05). Three months after operation, the scores of modified Rankin scale in both groups were significantly decreased compared with those before treatment, and the score in group A was significantly decreased compared with group B (P< 0.01). Compared with the preoperative scores, the scores of neurologic function impairment scale in both groups decreased significantly at 3 months after operation, and the score in group A was significantly decreased compared with those in group B (P< 0.01). Compared with pre-operation, the scores of SF-36 scale in two groups were significantly higher at 3 months after operation, and the scores in group A were significantly higher than those in group B (P< 0.05). Conclusion: Compared with the patients whose time between onset and treatment is more than 72 hours, interventional embolization within 72 hours can effectively improve the clinical efficacy of intracranial aneurysms, and play an important role in improving the prognosis, neurological function and quality of life of patients. Therefore, it should be popularized in clinic.
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2019, Vol. 25 
