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Effect of Azithromycin combined with Tebutaline Inhalation on Inflammatory Factors and Immune Function in Children with Mycoplasmal Pneumonia |
XIAO Yun, WANG Jiangang, ZHANG Di |
Yingkou Central Hospital, Liaoning Yingkou 115002, China |
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Abstract Objective: To investigate the effects of azithromycin combined with teptoline inhalation on inflammatory factors and immune function in children with mycoplasmal pneumonia. Methods: A retrospective analysis of 70 children with mycoplasmal pneumonia admitted to our department from January 2015 to January 2018. All children were divided into two groups according to different treatment methods. 30 patients in the control group were given oral azithromycin tablets. treatment. Forty patients in the combined treatment group were given nebulized inhalation therapy with pedicalin on the basis of the control group. Both groups were treated for 7 days. Results: Before treatment, TNF-α was combined treatment group (70.35±3.62) pg/ml, control group (69.94±4.10) pg/ml; hs-CRP was combined treatment group (22.27±5.67) pg/ml, control Group (21.99±5.02) pg/ml, the difference was not statistically significant. After treatment, TNF-α and hs-CRP were significantly decreased in the two groups. TNF-α was (34.03±3.72) pg/ml in the combination group and (21.99±5.02) pg/ml in the control group; hs-CRP They were (8.32±2.17) pg/ml, (13.48±3.75) pg/ml, and difference is significant (P<0.05). There were no significant differences in the immunological function between the two groups before treatment (P>0.05). After treatment, IgA, IgG, C3, and C4 were significantly increased in the two groups, the difference is significant(P<0.05), and the combination treatment group was significantly better than the control group(P<0.05). The time of disappearance of fever, the time of disappearance of sputum, the time of disappearance of cough and the length of hospital stay were significantly shorter in the combined treatment group than in the control group, and the difference was not statistically(P<0.05). Conclusion: The use of azithromycin combined with teptoline inhalation in children with mycoplasmal pneumonia can better improve the inflammatory factor level and immune function of children, so that children can recover their body temperature, eliminate their voices and cure cough in a short time. Early sunrise, the effect is exact.
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[1] 龙瑜.布地奈德、特布他林雾化联合阿奇霉素治疗支原体肺炎48例临床疗效[J].吉林医学,2017,38(7):1314~1315. [2] 李彤.阿奇霉素联合特步他林雾化吸入在小儿支原体肺炎治疗中的效果观察[J].中国继续教育,2018,7(28):153~154. [3] 杜晓宁,梁丽霞,严慧芳,等.阿奇霉素序贯疗法联合特步他林治疗小儿支原体肺炎的临床观察[J].中国药房,2016(6):740~742. [4] 王彦军.阿奇霉素联合特步他林雾化吸入治疗小儿支原体肺炎的临床效果研究[J].继续医学教育,2017,31(2):150~152. [5] 缪华,刘晓蓉.特布他林联合阿奇霉素治疗小儿支原体肺炎的疗效[J].热带医学杂志,2017,17(12):1659~1663. |
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