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| Effects of Individualized Diet Cntrol and Kuangqi-sijunzi Decoction on Glucose Lipid, RBP4 levels and Maternal and Infant Complications in Pregnant Women with Gestational Diabetes Mellitus |
| YANG Ran, LU Guolian |
| Zunhua People's Hospital, Hebei Zunhua 064200, China |
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Abstract Objective: To analyze the effects of individualized diet control combined with huangqi-sijunzi decoction on the levels of glycolipid, retinol binding protein 4 (RBP4) and maternal and infant complications in pregnant women with gestational diabetes mellitus. Methods: 60 cases of gestational diabetes mellitus patients in our hospital from August 2016 to August 2018 were divided into two groups according to simple random grouping method. The control group was given individualized diet control, and the combined group was given individualized diet control combined with huangqi-sijunzi decoction, with 30 cases in each group. The changes of blood glucose, blood lipid, RBP4 levels before and after treatment and the occurrence of complications of puerpera and infant were compared between the two groups. Results: One month after treatment, the levels of fasting blood glucose (FBG), 2-hour postprandial blood glucose (2hPBG), triglyceride (TG), total cholesterol (TC) and low-density lipoprotein-cholesterol (LDL-C) in the two groups were significantly decreased compared with those before treatment, and the levels of high-density lipoprotein-cholesterol (HDL-C) were significantly increased compared with those before treatment in the combined group. After treatment, the levels of FBG, 2h PBBG, TG, TC and LDL-C were significantly decreased compared with those of the control group, and the level of HDL-C was significantly increased compared with the control group (P<0.05); compared with before treatment, the levels of RBP4 in the combined group were significantly lower after treatment and significantly lower than those in the control group (P<0.01), while there was no significant difference in the control group between and after treatment (P>0.05). The incidence of fetal growth restriction, intrauterine infection, intrauterine distress, amniotic fluid infection, cesarean section rate and macrosomia delivery rate in the combined group were significantly lower than those in the control group (P<0.05), but there was no significant difference in the incidence of postpartum hemorrhage, premature delivery and neonatal hypoglycemia between the two groups (P>0.05). Conclusion: Individualized diet control combined with huangqi-sijunzi decoction can effectively improve the levels of blood sugar, blood lipid and RBP4 in patients with gestational diabetes mellitus, reduce the occurrence of perinatal complications, and have important clinical significance in improving maternal and infant outcomes.
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2019, Vol. 25 
