乙肝患者血清HBeAg与HBV-DNA定量的相关性分析

doi:10.3969/j.issn.1006-6233.2019.05.27

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Abstract Objective: To analyze the correlation between HBeAg and HBV-DNA levels in patients with hepatitis B. Methods: A totol of 586 HBsAg positive serum samples were selected. The levels of the HBeAg and HBV-DNA were measured by the ELISA and fluorometric PCR, respectively. The relationship between the markers were analyzed. Results: Among the 586 patients, the detection rate of HBV-DNA in HBeAg positive group and negative group was 86.19 % and 29.46 % respectively, which showed there was significant difference (χ²=194.46, P<0.05) between the HBeAg positive group and negative group. The content of HBV-DNA in the HBeAg positive group was higher than in the HBeAg negative group. With the increase of the HBeAg content, the amount of HBV-DNA in the serum also increased(F=6.67, P<0.05). Conclusion: The HBeAg level is positive correlation with the HBV-DNA load. Simultaneous detection of HBeAg and HBV-DNA would be clinical most desirable.

Key words： Hepatitis B HBV-DNA Hepatitis B E antigen

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	CAI Xinglong

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CAI Xinglong. Analysis on Correlation between HBeAg and HBV-DNA Levels in Patients with Hepatitis B[J]. HeBei Med, 2019, 25(5): 820-822.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2019.05.27 OR http://www.hbyxzzs.cn/EN/Y2019/V25/I5/820

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