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| Analysis on Long-term Prognosis and Influencing Factors of Regular and Irregular Resection of Single Small Liver Cancer |
| HUANG Fengde, XU Dan, AN Zhiming, et al |
| Mianyang 404 Hospital in Sichuan, Sichuan Mianyang 621000, China |
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Abstract Objective: To analyze the long-term prognosis and influencing factors of regular and irregular resection of single small liver cancer. Methods: 89 patients with single small liver cancer who treated from May 2010 to May 2013 in our hospital, according to random number table method, those patients were divided into 40 cases of A group and 49 cases of B group,group A used regular resection and group B used irregular resection. The operation and complications in both groups were compared, and the influencing factors of long-term prognosis were analyzed. Results: The operation time, intraoperative blood loss, margin size and length of hospital stay in the irregular resection group were lower than those in the regular resection group (P<0.05). the total complication rate in the both groups was no significant difference (P>0.05). Univariate analysis showed that gender, age, Child-pugh grade, serum HbsAg, CGT, AEP, total bilirubin, ALT level, tumor margin, hepatic occlusion time, bleeding volume, and whether the rule was removed for 5 years were no significant difference in survival rate (P>0.05). there were significant differences in 5-year survival rates between different albumin levels, tumor size, tumor capsule, long-term smoking, and intraoperative blood transfusion (P<0.05). Cox regression analysis showed that tumor size and long-term smoking were independent risk factors for the prognosis of patients with single hepatocellular carcinoma, tumor envelope integrity and albumin levels were protective factors. Conclusion: The long-term prognosis of small hepatocellular carcinoma is related to various factors. Regular hepatectomy is not an independent prognostic factor, and the optimal operation should be selected clinically according to the tumor anatomical location and liver function reserve of patients.
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[1] 张扬,王黎明,吴凡,等.98例小肝癌患者的临床病理特征及预后分析[J].中华肿瘤杂志,2017,39(5):389~394.
[2] 张雅敏,王建.解剖性肝切除与非解剖性肝切除对肝癌预后影响的研究进展[J].中华外科杂志,2016,54(12):947~950.
[3] 施文武,游红勇,李兵.不同手术治疗原发性肝癌疗效及其预后影响因素分析[J].检验医学与临床,2014,11(9):1191~1192,1194.
[4] 丛文铭,步宏,陈杰,等.原发性肝癌规范化病理诊断指南(2015年版)[J].解放军医学杂志,2015,21(11):865~872.
[5] 葛万灵.规则性或非规则性肝癌切除术治疗单发小肝癌的预后分析[J].肝胆外科杂志,2017,25(3):181~185.
[6] 刘宝剑,贾光伟.肝规则切除与不规则切除治疗单发性小肝癌疗效对比[J].肝脏,2017,22(12):1157~1159.
[7] 林泽毅,朱少亮,黄山,等.单发小肝癌规则切除与非规则切除疗效及其预后因素分析[J].中华肿瘤防治杂志,2015,22(14):1128~1133.
[8] 苏瑛,龚昭.经手术切除的原发性小肝癌患者复发的危险因素分析[J].安徽医药,2014,18(7):1306~1308.
[9] 雪莹,苏丹柯,韦波,等.小肝细胞肝癌切除术后预后的相关因素分析[J].广西医科大学学报,2014,31(2):251~253.
[10] 刘清,刘斌,卜文平,等.老年肝癌患者行根治术治疗的临床特点及预后分析[J].中华老年医学杂志,2017,36(8):886~888.
[11] 苗润晨,许鑫森,陈伟,等.年龄因素对肝癌肝切除术患者长期预后的影响[J].现代肿瘤医学,2014,22(5):1123~1126.
[12] 钱波,万圣云,喻宗繁,等.原发性肝癌手术预后影响因素分析[J].安徽医科大学学报,2015,50(10):1479~1482.
[13] 李明岳,刘嘉林,郑锦锋,等.原发性肝癌患者手术治疗后生存状况的影响因素分析[J].实用癌症杂志,2014,29(7):802~804. |
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2019, Vol. 25 
