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The Efficacy of Glucocorticoid in the treatment of Children with Mycoplasma Pneumonia and Lobar Pneumonia |
YANG Lindong, ZHANG Yanfeng |
Yan'an People's Hospital, Shaanxi Yan'an 716000, China |
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Abstract Objective: To investigate the therapeutic effect of glucocorticoid therapy on mycoplasma pneumoniae pneumonia in children. Methods: A total of 100 children with mycoplasma pneumoniae pneumonia were enrolled from January 2016 to December 2016 were randomly divided into two groups. The control group was given routine treatment. The patients in the experimental group were treated with glucocorticoid therapy, The clinical indexes, drug side effects, lung function, inflammatory index, markedly effective rate and total effective rate were compared between the two groups. Results: The time of fever, cough remission, X-ray recovery time, rales disappearance and hospitalization time were significantly lower in the experimental group than in the control group. After treatment, FEF50, FEF75 and FEF25-75 were significantly The levels of IL-1β, IL-2, IL-4, IL-6, CRP, ESR, TNF-α and INF-γ were significantly lower than those of the control group In the control group, there was significant difference (P <0.01). Conclusion: Glucocorticoid therapy is effective in the treatment of mycoplasma pneumoniae lobular pneumonia in children.
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[1] 吴爱民,陈强,刘建梅,等.糖皮质激素在儿童难治性肺炎支原体肺炎中的应用[J].中华实用儿科临床杂志,2014,29(10):797~799. [2] 胡亚美,江载芳,吴瑞萍.实用儿科学[M].北京.人民卫生出版社,1957.1132~1140. [3] 饶友花.糖皮质激素对肺炎支原体肺炎患儿使用的相关因素分析与临床护理[J].河南中医,2014,34(B06):406~406. [4] 梅玉霞.抗生素联合糖皮质激素治疗重症支原体肺炎对患儿临床症状、炎性指标和细胞免疫的影响[J].河北医药,2016,38(6):883~885. [5] 沈彤,刘成军,刘茂花.小剂量糖皮质激素联合小潮气量、肺复张在重症肺炎肺损伤患儿中的应用[J].儿科药学杂志,2016,22(7):8~10. [6] 林炜.早期应用小剂量糖皮质激素治疗儿童重症肺炎的效果分析[J].现代诊断与治疗,2015,26(16):3608~3609. [7] 陈丽萍,陈军辉,陈颖,等.糖皮质激素治疗社区获得性肺炎疗效及安全性Meta分析[J].中华急诊医学杂志,2014,23(1):65~70. [8] 姚欢银,张佩红,童海明.血清糖皮质激素受体在难治性肺炎支原体肺炎患儿中的变化及临床意义[J].医学研究杂志,2016,45(10):82~85. [9] 吴跃进,孙节.糖皮质激素辅助治疗儿童肺炎支原体大叶性肺炎的疗效[J].中国当代儿科杂志,2014,16(4):401~405. [10] 丁圣刚,王建.糖皮质激素在治疗儿童重症肺炎支原体肺炎(MPP)中的价值[J].复旦学报:医学版,2012,39(2):180~183. [11] 王彬彬.新生儿肺炎支原体肺炎26例临床分析[J].中国妇幼保健,2012,27(25):4008~4009. [12] 陈丽兰.常量甲泼尼龙治疗无效的儿童难治性肺炎支原体肺炎的临床特征和治疗方案探讨[J].河北医学,2016,22(1):147~150. |
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