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Dexmedetomidine Combined with Bispectral Index Monitoring on Hemodynamics during General Anesthesia Recovery and Extubation in Patients Undergoing Radical Resection of Lung Cancer |
CHEN Meng, HE Huan, LI Dechun, et al |
The First People's Hospital of Yulin, Guangxi Yulin 537000, China |
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Abstract Objective: To investigate the effects of dexmedetomidine combined with bispectral index applied on hemodynamics of patients with lung cancer effects during anesthesia recovery period and pull. Methods: 60 patients admitted in our hospital from January to December 2016 enrolled in this study were the need for radical lung cancer, were given the same dose of dexmedetomidine and other drugs for induction of anesthesia, surgery according to the clinical experience of infusion of propofol, remifentanil and intermittent intravenous injection of CIS atracurium to maintain the depth of anesthesia. In the observation group, 30 cases maintained bispectral index (BIS) between 40 and 60, and adjusted the amount of propofol according to the monitoring results. The respiratory and consciousness recovery time and the total amount of narcotic drugs were compared between the 2 groups. The hemodynamic indexes of the 2 groups were observed during the extubation, and the incidence of adverse reactions in the 2 groups was counted. Results: The hemodynamics observation group' is more stable (P<0.05); The total amount of remifentanil, were significantly lower than the control group (P <0.05); the observation group breathing recovery time, extubation time, orientation recovery time was significantly lower than the control group (P<0.05); the incidence of adverse reaction the observation group during the extubation was significantly lower than the control group (P<0.05). Conclusion: Dexmedetomidine combined with bispectral index in lung cancer patients blood flow dynamics is stable, can reduce the total use of narcotic drugs, recovery time shortened, and safety.
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