|
|
|
| Risk Factors of Pulmonary Embolism in Hospitalized Patients with AECOPD Deduced by Non-dominant Factors |
| LI Junhua, ZHANG Shiguo, CHEN Zhiyong, et al |
| Bazhong Central Hospital, Sichuan Bazhong 636000, China |
|
|
|
|
Abstract Objective: To investigate the risk factors of pulmonary embolism (PE) in patients with chronic obstructive pulmonary disease (COPD) deduced by non-dominant factors in order to provide the basis for clinical treatment. Methods: 184 patients with AECOPD deduced by non-dominant factors in our hospital were selected and divided into two groups, 60 patients in pulmonary embolism group and 122 patients in non-pulmonary embolism group. The past disease history, general information, auxiliary examination results, clinical symptoms and COPD severity grading of the two groups were compared. Then the risk factors were analyzed by Logistic regression analysis. Results: There was no statistically significant difference in the general information, COPD severity grading, past disease history and clinical symptoms of the two groups (P>0.05).In the pulmonary embolism group, 25.0% patients' bed time was more than one week, 36.67% patients' difference of the two limb circumference was no less than 1cm, 28.33% patients' PCO2 was no more than 36mmHg, 38.33% patients had deep venous thrombosis, and 98.33% patients' D Dimer was no less than 500μg/L. Compared with the pulmonary embolism group, the indexes of the non-pulmonary embolism group were significantly better than those of the pulmonary embolism group (P<0.05). According to the Logistic regression analysis, the time in bed more than one week, the difference of the two limbs circumference no less than 1cm, and deep venous thrombosis were the three main risk factors for AECOPD deduced by non-dominant factors. Conclusion: There are three main risk factors for AECOPD deduced by non-dominant factors including the time in bed more than one week, the difference of the two limbs circumference no less than 1cm, and deep venous thrombosis. The possibility of PE should be paid more attention to in order to avoid misdiagnosis.
|
|
|
| Fund:四川省卫生计划委员会资助项目,(编号:201403252) |
|
|
|
[1] 林英翔.慢性阻塞性肺疾病合并肺栓塞的问题值得关注[J].中华结核和呼吸杂志,2013,36(4):253~254.
[2] 王颖,钟红,杨福祥,等.AECOPD合并肺栓塞48例临床分析[J].临床肺科杂志,2011,16(6):941~942.
[3] 董昭兴,张涛,李永霞,等.肺栓塞在COPD急性加重期中的作用[J].中国呼吸与危重监护杂志,2010,09(6):652~653.
[4] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8~17.
[5] Chen H.,Wang Y, Bai C, et al. Alterations of plasma inflammatory biomarkers in the healthy and chronic obstructive pulmonary disease patients with or without acute exacerbation[J]. Journal of proteomics, 2012, 75(10): 2835~2843.
[6] Bertoletti L, Regamey N, Jeffery P K,et al. The cloud of pulmonary embolism during COPD exacerbation[J].Thorax, 2012, 67(2): 177~178.
[7] Kline J A, Hogg M.M, Courtney D.M, et al. D-dimer threshold increase with pretest probability unlikely for pulmonary embolism to decrease unnecessary computerized tomographic pulmonary angiography[J].Journal of thrombosis and haemostasis, 2012, 10(4): 572~581.
[8] Choi K J, Cha S I, Shin K M, et al. Prevalence and predictors of pulmonary embolism in korean patients with exacerbation of chronic obstructive pulmonary disease[J].Respiration, 2013, 85(3): 203~209. |
|
|
|
2017, Vol. 23 
