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| Analysis on Relationship between Urinary Albumin Excretion with Diabetic Retinopathy in Type 2 Diabetics |
| SUN Guanyuan, WANG Ying |
| The Affiliated Hospital of Logistics Institute of Chinese People's Armed Police Forces, Tianjin 300162, China |
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Abstract Objective: To analyze the relationship between urinary albumin excretion with diabetic retinopathy in type 2 diabetics. Methods: 320 patients with type 2 diabetics were divided into normal albuminuria group(NA, n=68, 24h-urinary albumin≤30mg), microalbuminuria group(MAU, n=135, 30mg＜24h-urinary albumin＜300mg) and macroalbuminuria group(CAU,n=117,24h-urinary albumin≥300mg) . All the patients were measured the 24h-urinary albumin and examined by digital retinal photographs, thus we can analyze the relationship between urinary albumin excretion with diabetic retinopathy in type 2 diabetics. Results: Simple retinopathy detection were 10.1%,42.9% and 43.3% in normal albuminuria group, microalbuminuria group and macroalbuminuria group, fertile retinopathy detection rate were 5.2%,15.8% and 35.4% in the 3 groups , statistically significant differences existed in the rate of simple retinopathy detection and fertile retinopathy detection of different groups(P＜0.05). Correlation analysis results showed that there is positive correlation between urinary protein excretion and diabetic retinopathy in patients with type 2 diabetes(r=0.526, P＜0.05). Conclusion: Urinary protein excretion were significantly correlated with the incidence of diabetic retinopathy in patients with type 2 diabetes, maybe they have common pathophysiological basis.
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| Fund:天津市科技计划项目,(编号:201321184) |
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[1] 齐丽艳.关于糖尿病的新诊断标准与分型[J].求医问药(学术版),2013,11(1):195.
[2] Shu-Chiung C,Jenn-Kuen L,Chih-Hung C,et al.Justifying the high prevalence of microalbuminuria for type 2 diabetic patients in Taiwan with conditional probability approach—a DEMAND II Study[J].Journal of the Chinese Medical Association,2011,74(1):3~10.
[3] 刘慧慧,甄东户,郭晓颖,等.不同糖代谢人群中微量清蛋白尿患病率及影响因素调查分析[J].中国全科医学,2013,16(15):1747~1751.
[4] Qureshi A I,Suri M F,Kirmani J F,et al.Prevalence and trends of prehypertension and hypertension in United States:National Health and Nutrition Examination Surveys 1976 to 2000[J].Medical Science Monitor International Medical Journal of Experimental Clinical Research,2005,11(9):CR403~409.
[5] Mehrab-Mohseni M,Tabatabaei-Malazy O,Hasani-Ranjbar S,et al.Endothelial nitric oxide synthase VNTR(intron 4 a/b)polymorphism association with type 2 diabetes and its chronic complications[J].Diabetes Research Clinical Practice,2011,91(3):348~352.
[6] 万倩,张倩,薛耀明,等.2型糖尿病肾病患者白蛋白尿的危险因素分析[J].实用医学杂志,2015,31(8):1234~1237. |
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2017, Vol. 23 
