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| Correlation Analysis on EGFR c-Met and Ki-67 in Gastric Cancer with Intravascular Cancer Embolus |
| WANG Aimin, et al |
| The Central Hospital of Chengde, Hebei Chengde 067000, China |
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Abstract Objective: To analyze the expression of EGFR, c-Met and Ki-67 in gastric cancer with intravascular cancer embolus and their influence on the prognosis. Methods: The expression of EGFR, c-Met and Ki-67 in 88 gastric cancer cases and 39 cases of intravascular cancer embolus were detected and the difference between 1-year and 3-year survival rate in cancer embolus positive and negative patients group were analyzed. Results: In gastric cancer tissue with intravascular cancer embolus, the strong positive expression rates of EGFR, c-Met and Ki-67 were all higher than those in gastric cancer tissue without intravascular cancer embolus (P<0.05). The strong positive expression rates of EGFR, c-Met and Ki-67 in gastric cancer tissue without intravascular cancer embolus 1-year and 3-year survival rate were obviously higher than those of cancer embolus positive group (P<0.05). Conclusions: The expression and prognosis of EGFR, c-Met and Ki-67 are related to the gastric cancer with intravascular cancer embolus, and has rather poor prognostic significance in gastric cancer.
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2017, Vol. 23 
