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| Tremor Analysis and External Anal Sphincter Electromyography in Patients with Parkinson's Disease and P-Type Multiple System Atrophy |
| LI Hailiang, CHENG Yanbo, DONG Ruiguo, et al |
| The Affiliated Hospital of Xuzhou Medical University, Jiangsu Xuzhou 221000, China |
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Abstract Objective: To investigate the differences in tremor analysis and external anal sphincter electromyography(EAS-EMG) in Parkinson's disease (PD)and P-type Multiple system Atrophy patients ( MSA-P).Methods: Fifty PD patients and twenty-five MSA-P patients treated at the Department of Neurology, Affiliated Hospital of Xuzhou Medical University, were selected. According to the H&Y staging, PD patients were divided into early-middle stage PD group (H&Y 0-3, 27 cases) and late-stage PD group (H&Y 4~5, 23 cases), along with the MSA-P group (25 cases). Tremor analysis and EAS-EMG were performed for all three groups, and the differences in various indices of tremor analysis and EAS-EMG among the three groups were analyzed.Results: The incidence of resting tremor was higher in the PD group compared to the MSA-P group (P<0.05), with no significant differences in tremor frequency and postural tremor incidence. In the early-middle stage PD group, both resting tremor and postural tremor frequencies were higher than in the late-stage PD group (P<0.05), with resting tremor being predominant in both groups. However, there were no statistically significant differences in the incidence of resting tremor and postural tremor between the two groups (P>0.05). The incidence of resting tremor was higher in the early-middle stage PD group compared to the MSA-P group (P<0.05), with no significant difference in the incidence of postural tremor. Compared with the PD group, the MSA-P group had a prolonged average duration of motion unit of the anal sphincter during slight contraction (MUAP), a significantly higher percentage of polyphasic waves, and a higher incidence of satellite potentials (P<0.05). In the late-stage PD group compared to the early-middle-stage PD group, there was a prolonged average duration of MUAP, a significantly higher percentage of polyphasic waves, and a higher incidence of satellite potentials (P<0.05). Compared to the MSA-P group, the early-middle stage PD group had a shorter average duration of MUAP (P<0.05), a lower percentage of polyphasic waves, and a lower incidence of satellite potentials (P<0.05).Conclusion: Tremor analysis and EAS-EMG are associated with the progression of Parkinson's disease and may provide a basis for differentiating between MSA-P and early-middle-stage PD patients.
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2024, Vol. 30 
