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| Efficacy Observation of Zishui Qingxin Formula in the Treatment of Insomnia in Menopausal Women |
| QUAN Xingmiao, LIU Yulan, WANG Yue, et al |
| Affiliated Hospital of Chengde Medical University, Hebei Chengde 067000, China |
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Abstract Objective: To observe and analyze the clinical effect of Zishui Qingxin Formula on menopause insomnia. Methods: Eighty menopausal women with insomnia admitted to our hospital from March 2017 to December 2019 were randomly divided into a control group (40 patients) and a treatment group (40 patients). The control group received conventional treatment, while the treatment group received Zishui Qingxin Formula in addition to the control group. After treatment, the traditional Chinese medicine syndrome scores, weekly sleep quality (PSQI), and polysomnography (PSG) parameters were observed and compared between the two groups. Results: After treatment, TCM syndrome score, PSQI, PSG parameters (wake times, wake time, sleep latency, fast wave sleep latency) were lower than before treatment (P<0.05), PSG parameters (sleep efficiency, fast wave sleep, slow wave sleep) were higher than before treatment (P<0.05), and the treatment group was better than the control group (P<0.05). The total effective rate of the treatment group (95%) was higher than that of the control group (77.5%) (P<0.05). Conclusion: Zishui Qingxin Formula is effective in the treatment of menopausal insomnia patients, and can effectively improve insomnia symptoms and sleep quality.
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[1] Sheida Z,Chun Y,Cynthia T,et al.Effects of menopause on sleep quality and sleep disorders:canadian Longitudinal Study on Aging.[J].Menopause (New York,N.Y.),2020,27(3):295-304
[2] 孙星,王燕,郗轶楠等.激素替代治疗对更年期综合征患者的临床效果及对治疗依从性的影响因素分析[J].中国性科学,2021,30(9):74-76.
[3] 鞠文雪,姚娓.失眠中医内治、外治法临床进展[J].辽宁中医药大学学报,2023,25(1):147-151.
[4] 谢幸,孔北华,段涛.妇产科学[M].北京:人民卫生出版社,2018.
[5] 贾建平,陈生弟.神经病学[M].北京:人民卫生出版社,2018.
[6] 刘泰,谌剑飞.中西医结合睡眠障碍诊疗学[M].中国中医药出版社,2011.
[7] 张帅美,邓丽影,丁勇民.睡眠相关节律性运动不同临床表型的多导睡眠图特征[J].中风与神经疾病杂志,2020,37(11):968-972.
[8] Baykara S,Alban K.The effects of buprenorphine/naloxone maintenance treatment on sexual dysfunction,sleep and weight in opioid use disorder patients[J].Psychiatry Research,2019,272(22):450-453.
[9] 邹正,史佳芯,梁国标等.基于“水火既济”理论从“心-肾-脑-神轴”探析老年抑郁症[J].中华中医药学刊,2022,40(2):234-237.
[10] 严斐霞,谢永艳,陈畅等.熟地黄炮制过程中的化学成分变化和药理作用研究进展[J].时珍国医国药,2021,32(10):2493-2495.
[11] 王梅爱.北五味子提取物对失眠大鼠模型海马组织内GABA＿ARα1、GABA＿ARγ2、的影响[J].世界睡眠医学杂志,2021,8(11):1916-1918.
[12] 韦凌霞,丁茂鹏,王志旺,姚楠,庞亚蓉.基于网络药理学探讨山茱萸-牡丹皮药对抗肝纤维化作用机制[J].中国新药与临床杂志,2021,40(1):64-70. |
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2024, Vol. 30 
