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| Clinical Efficacy and 5-Year Follow-up Analysis of Breast Conserving Surgery for TNBC Patients |
| ZHAI Rui, QI Jing, MA Xiaoxia |
| The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Xi'an 710061, China |
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Abstract Objective: To analyze the effect of breast conserving surgery in triple negative breast cancer (TNBC). Methods: A total of 124 cases of early TNBC patients admitted to our hospital from February 2015 to December 2017 were selected, and the surgical plan was chosen according to the wishes of patients and their families, their own conditions, surgical indications and contraindications, and divided into observation and control groups, 60 cases in the control group were treated with modified radical surgery, and 64 cases in the observation group were treated with breast-conserving surgery. Comparison of intraoperative condition, hospitalization time, recent efficacy after treatment, postoperative shoulder mobility, postoperative complications, psychological function, somatic function, social function scores, and 5-year postoperative follow-up between the two groups. Results: The hospitalization time, operation duration, objective remission rate, disease control rate, postoperative rate of local recurrence rate, and distant metastasis rate of the two groups were compared, and there was no difference (P>0.05); intraoperative bleeding, postoperative drainage, and the total incidence of complications in the observation group were lower than those in the control group (P<0.05); and the postoperative flexion, abduction, posterior extension, internal rotation, external rotation mobility, psychological function, somatic function and social function scores were elevated more than those of patients in the control group (P<0.05). Conclusion: Breast-conserving surgery for the treatment of early TNBC has no significant difference in recent efficacy, 5-year postoperative local recurrence rate, and distant metastasis rate compared with modified radical surgery. Breast-conserving surgery has less intraoperative bleeding and postoperative drainage, greater shoulder mobility, fewer complications, and higher postoperative quality-of-life scores, and is worthwhile to popularize its use in the clinic.
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[1] 童富云,徐美玲,张超,等.磁共振多序列成像在三阴性乳腺癌新辅助化疗后保乳手术中的应用[J].重庆医学,2021,50(21):3687-3690.
[2] 郑淑萍,曹呈尧.保乳联合前哨淋巴结活检术治疗早期三阴性乳腺癌的疗效及对术后生活质量的影响[J].中国妇幼保健,2022,37(1):48-51.
[3] 方文成,宗守凯,张传平.保乳术联合前哨淋巴结活检治疗早期三阴性乳腺癌的临床研究[J].中国现代普通外科进展,2022,25(8):636-638.
[4] 邓兰,尹静,许思哲.改良根治术治疗三阴性乳腺癌的效果及预后影响因素分析[J].湖南师范大学学报(医学版),2021,18(6):215-218.
[5] 刘振宇,范志民.乳腺癌新辅助化疗后行保乳手术值得关注的问题[J].中国实用外科杂志,2021,41(11):1226-1230.
[6] 吴松阳,江一舟,邵志敏.三阴性乳腺癌治疗进展[J].中国普通外科杂志,2021,30(5):510-521.
[7] 刘心烛,左怀全.老年三阴性乳腺癌患者术后预后影响因素分析[J].中国普外基础与临床杂志,2021,28(3):341-344.
[8] 阿依努尔阿力比亚提·艾尼.早期乳腺癌患者保乳术联合术后放疗与乳房全切术的疗效对比[J].现代肿瘤医学,2022,30(9):1608-1613.
[9] 王宋,邓建,吕红英,等.基于SEER数据库分析保乳术和乳房切除术对不同淋巴结转移状况的T1期三阴性乳腺癌预后的影响[J].中国临床研究,2021,34(8):1014-1018.
[10] 王晓东,陈大鹏,彭永强.保乳手术治疗早期三阴乳腺癌患者的效果及安全性[J].中国医药导报,2022,19(8):109-112. |
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2023, Vol. 29 
