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The Effect of Internal and External Therapies in the Treatment of Children with Pneumonia and Effect on Procalcitonin hs-CRP and Immune Function |
ZHANG Huali, WANG Chao, ZHANG Rui, et al |
The First Hospital of Shijiazhuang, Hebei Shijiazhuang 050011, China |
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Abstract Objective: To find a new therapy for the treatment of pneumonia in children, to explore the clinical effect of combined internal and external treatment. Methods: 200 cases of pneumonia patients were classified as the observation group and control group, each with 100 cases. The control group was treated with symptomatic treatment, the observation group based on the use of internal and external therapies in the control group. The treatment effect and the levels of hs-CRP, PCT, CD4+, CD4+/CD8+, Treg and CD4+CD25+ of two groups were observed. Results: After treatment, the curative effect of observation group was significantly better than the control group (P < 0.05). Before treatment, the hs-CRP level of observation group and control group was higher than that in healthy control group (P < 0.05), after treatment, there was no significant difference between the observation group patients and healthy control group, while the control group, the level of hs-CRP was slightly higher than that in the healthy control group (P < 0.05). Before treatment, the PCT level of observe group and control group was higher than that of the healthy control group (P < 0.05), after treatment, the observation group patients and healthy control group (P < 0.05), while the control group, the level of PCT was slightly higher than that in the healthy control group (P < 0.05). Before treatment, the levels of CD4+, CD4+/CD8+, Treg CD4+CD25+ in the observation group and the control group were lower than those in the healthy control group (P < 0.05). After treatment, there was no significant difference between the observation group and healthy control group, while the levels of CD4+CD25+, CD4+/CD8+ and Treg CD4+ in the control group were slightly higher than those in the healthy control group (P < 0.05). Conclusion: Combining internal and external therapy in the treatment of infantile pneumonia, the curative effect is significant, and can effectively improve children's hs-CRP, PCT, CD4 +, CD4 + / CD8 + and CD4 + CD25 + Treg levels.
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