CMR-FT成像技术定量评估扩张型心肌病预后的预测价值

doi:10.3969/j.issn.1006-6233.2023.06.027

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Abstract Objective: To investigate the predictive value of cardiac magnetic resonance signature tracking (CMR-FT) imaging for quantitative assessment of myocardial strain before and after treatment for dilated cardiomyopathy (DCM) on prognosis. Methods: Ninety-four patients with DCM admitted to our hospital from April 2018 to April 2021 were selected and given standard treatment according to guideline recommendations and followed up for 6 months, and divided into poor prognosis group (MACE occurred, 23 cases) and good prognosis group (no MACE occurred, 71 cases) according to whether major adverse cardiovascular events (MACE) occurred, and clinical data and cardiac function indexes before and after treatment were compared between the two groups [left ventricular ejection fraction (LVEF), amino-terminal brain natriuretic peptide precursor (NT-proBNP)], myocardial strain parameters [total strain (εs), passive strain (εe), active strain (εa), peak positive left ventricular systolic strain rate (SRs), peak negative left atrial strain rate in early left ventricular diastole (SRe), peak negative left atrial strain rate in late left ventricular diastole ( SRa)], to analyze the correlation between each myocardial strain parameter and cardiac function indexes, and to evaluate the prognostic impact and predictive value of the difference of each myocardial strain parameter before and after treatment. Results: LVEF before and after treatment was lower in the poor prognosis group than in the good prognosis group [(45.27±3.62)% versus (49.82±4.30)%, t=4.572, P<0.05, (48.96±4.15)% versus (56.41±5.03)%, t=6.423, P<0.05], and NT-proBNP was higher in the good prognosis group [( 1275.84±326.55) pg/mL versus (1014.79±259.87) pg/mL, t=3.924, P<0.05 and (1001.35±241.98) pg/mL versus (665.21±202.43) pg/mL, t=6.591, P<0.05]. The pre- and post-treatment εs, εe, εa, SRs, SRe, SRa and differences were smaller in the poor prognosis group than in the good prognosis group (all P<0.05); myocardial strain parameters were positively correlated with LVEF and negatively correlated with NT-proBNP before and after treatment (all P<0.05); logistic regression analysis showed that myocardial strain parameter differences all had a significant effect on prognosis (all P< Logistic regression analysis showed that the difference in myocardial strain parameters had a significant effect on prognosis (all P<0.05). Conclusion: The application of CMR-FT imaging for quantitative assessment of myocardial strain in patients with DCM has some predictive value for prognosis and provides a reference for the risk of poor prognosis in patients with DCM.

Key words： CMR-FT Imaging technique Dilated cardiomyopathy Myocardial strain Predictive value

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	ZHAO Bingyang
	WEN Meixia

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ZHAO Bingyang,WEN Meixia. Predictive Value of CMR-FT Imaging for Quantitative Assessment of Prognosis in Dilated Cardiomyopathy[J]. HeBei Med, 2023, 29(6): 1020-1025.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2023.06.027 OR http://www.hbyxzzs.cn/EN/Y2023/V29/I6/1020

[1] Cojan-Minzat BO,Zlibut A,Muresan ID,et al.Left ventricular geometry and replacement fibrosis detected by cMRI are associated with major adverse cardiovascular events in nonischemic dilated cardiomyopathy[J].Clin Med,2020,9(6):1997.
[2] 刘修颖,孙阳,冉海涛,等.二维斑点追踪技术评价不同等级左心室舒张功能不全心力衰竭患者的右心室功能[J].中华超声影像学杂志,2020,29(7):564-570.
[3] 侯洁,孙玉,张立波,等.磁共振特征追踪技术评估风湿性二尖瓣狭窄合并房颤左心房心肌应变应用研究[J].磁共振成像,2022,13(4):107-110.
[4] 中华医学会心血管病学分会,中国心肌炎心肌病协作组.中国扩张型心肌病诊断和治疗指南[J].临床心血管病杂志,2018,34(5):421-434.
[5] 余鎏,夏睿,陶黎,等.扩张型心肌病患者心肌应变与左心室球形指数相关性的初步研究[J].中国医疗设备,2021,36(10):113-116.
[6] Rosenbaum AN,Agre KE,Pereira NL.Genetics of dilated cardiomyopathy:practical implications for heart failure management[J].Nat Rev Cardiol,2020,17(5):286-297.
[7] Urmeneta Ulloa J,Pozo Osinalde E,Rodriguez-Hernandez JL,et al.Myocardial strain in nonischemic dilated cardiomyopathy with feature tracking.Feasibility and prognostic implications[J].Rev Esp Cardiol (Engl Ed),2021,74(2):159-166.
[8] 张莉莎,郜发宝.CMR对扩张性心肌病的应用价值[J].国际医学放射学杂志,2022,45(2):157-162,200.
[9] 张艳,赵燕,吴昆华,等.心脏磁共振特征追踪技术在检测成人非梗阻性肥厚型心肌病患者心肌纤维化中的应用[J].中华心力衰竭和心肌病杂志,2021,05(1):30-34.
[10] 任诗君,李华侨,周丹丹.磁共振特征追踪技术对DCM患者心肌应变的评估及与心肌酶谱的关系[J].河北医药,2021,43(16):2442-2445,2450.
[11] 高雨洁,徐怡,廖深根,等.非缺血性扩张型心肌病患者NT-proBNP与心脏磁共振初始T1值的相关性[J].中国医学影像学杂志,2022,30(7):669-675.