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| The Application and Clinical analysis of Platelet - rich Plasma in the Treatment of Knee Osteoarthritis |
| FU Ligong, CHEN Lianxu |
| Changchun Hospital, Tsinghua University, Beijing 102218, China |
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Abstract Objective: To investigate the effect of platelet-rich plasma in the treatment of knee osteoarthritis. Methods: 67 Patients with osteoarthritis of the knee were selected from January 2015 to December 2016. The patients were divided into sodium hyaluronate injection control group (34 cases) and platelet-rich plasma injection group (33 cases). The scores of Lysholm knee function scores and VSA pain scores were compared between the two groups before and after treatment. Results: Compared with the control group, the total effective rate of the patients was significantly higher than that of the control group, and the difference was significant (P＜ 0.05). The difference of Lysholm knee function scores between the two groups before treatment was no significant (P ＞0.05). After 1 months of treatment, the Lysholm knee function scores increased significantly, and the difference was significant (P <0.01). After 6 months of treatment, Lysholm knee function scores were down, the control group scores fell as that before injection. While the experimental group, although reduced, but still better than pre-injection score. There was still significant difference between the two groups (P＜0.05). There was no significant difference of the VSA scores between the two groups (P>|0.05). After 1 months of treatment, the VSA scores of the two groups were improved, with the VSA scores of experimental group lower than that of the control group (P＜0.05). But after 6 months of treatment, the VSA scores were significantly decreased in the two groups. The VSA scores of experimental group were still lower than that of the control group, the difference was statistically significant (P <0.05). Conclusion: The use of platelet-rich plasma injection for the treatment of osteoarthritis of the knee is more effective than the sodium hyaluronate injection method, with better knee function recovery and more pain remission, and the effective time is longer. It's worthy for clinical promotion, with reference.
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2017, Vol. 23 
