[1] Sung H,Ferlay J,Siegel RL,et al.Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].Ca Cancer Clin,2021,71(3):209-249.
[2] Mili N,Paschou SA,Goulis DG,et al.Obesity,metabolic syndrome,and cancer:pathophysiological and therapeutic associations[J].Endocrine,2021,74(3):478-497.
[3] Raglan O,Kalliala I,Markozannes G,et al.Risk factors for endometrial cancer:an umbrella review of the literature[J].Int Cancer,2019,145(7):1719-1730.
[4] Lee CH,Woo YC,Wang Y,et al.Obesity,adipokines and cancer:an update[J].Clin Endocrinol (Oxf) 2015,83(2):147-156.
[5] Scherer PE,Williams S,Fogliano M,et al.A novel serum protein similar to C1q,produced exclusively in adipocytes[J].Biol Chem,1995,270(45):26746-26749.
[6] de Gennaro G,Palla G,Battini L,et al.The role of adipokines in the pathogenesis of gestational diabetes mellitus[J].Gynecol Endocrinol,2019,35(9):737-751.
[7] Yunusova NV,Kondakova IV,Kolomiets LA,et al.Molecular targets for the therapy of cancer associated with metabolic syndrome (transcription and growth factors)[J].Asia Pac Clin Oncol,2018,14(3):134-140.
[8] Kim DS,Scherer PE.Obesity,diabetes,and increased cancer progression[J].Diabetes Metab,2021,45(6):799-812.
[9] Ashizawa N,Yahata T,Quan J,et al.Serum leptin-adiponectin ratio and endometrial cancer risk in postmenopausal female subjects[J].Gynecol Oncol,2010,119(1):65-69.
[10] Wang Z,Gao S,Sun C,et al.Clinical significance of serum adiponectin and visfatin levels in endometrial cancer[J].Int Gynaecol Obstet,2019,145(1):34-39.
[11] Zheng Q,Wu H,Cao J.Circulating adiponectin and risk of endometrial cancer[J].Plos One,2015,10(6):129824.
[12] Dimou NL,Papadimitriou N,Mariosa D,et al.Circulating adipokine concentrations and risk of five obesity-related cancers:a mendelian randomization study[J].Int Cancer,2021,148(7):1625-1636.
[13] Katira A,Tan PH.Evolving role of adiponectin in cancer-controversies and update[J].Cancer Biol Med,2016,13(1):101-119.
[14] Hardie DG,Ross FA,Hawley SA.AMPK:a nutrient and energy sensor that maintains energy homeostasis[J].Nat Rev Mol Cell Biol,2012,13(4):251-262.
[15] Yan Y,Shi H,Zhao Z,et al.Adiponectin deficiency promotes endometrial carcinoma pathogenesis and development via activation of mitogen-activated protein kinase[J].Pathol,2022,257(2):146-157.
[16] Hayes MP,Wang H,Espinal-Witter R,et al.PIK3CA and PTEN mutations in uterine endometrioid carcinoma and complex atypical hyperplasia[J].Clin Cancer Res,2006,12(20):5932-5935.
[17] Yabushita H,Iwasaki K,Obayashi Y,et al.Clinicopathological roles of adiponectin and leptin receptors in endometrial carcinoma[J].Oncol Lett,2014,7(4):1109-1117.
[18] Hebbard LW,Garlatti M,Young LJ,et al.T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model[J].Cancer Res,2008,68(5):1407-1416.
[19] Zhang Y,Proenca R,Maffei M,et al.Positional cloning of the mouse obese gene and its human homologue[J].Nature,1994,372(6505):425-432.
[20] Kumar R,Mal K,Razaq MK,et al.Association of leptin with obesity and insulin resistance[J].Cureus,2020,12(12):e12178.
[21] Wang PP,He XY,Wang R,et al.High leptin level is an independent risk factor of endometrial cancer:a meta-analysis[J].Cell Physiol Biochem,2014,34(5):1477-1484.
[22] Shetty A,Venkatesh T,Tsutsumi R,et al.Gene expression changes and promoter methylation with the combined effects of estradiol and leptin in uterine tissue of the ovariectomized mice model of menopause[J].Mol Biol Rep,2020,47(1):151-168.
[23] Daley-Brown D,Harbuzariu A,Kurian AA,et al.Leptin-induced notch and IL-1 signaling crosstalk in endometrial adenocarcinoma is associated with invasiveness and chemoresistance[J].World Clin Oncol,2019,10(6):222-233.
[24] Zou S,Tong Q,Liu B,et al.Targeting STAT3 in cancer immunotherapy[J].Mol Cancer,2020,19(1):145.
[25] Daley-Brown D,Oprea-Ilies GM,Lee R,et al.Molecular cues on obesity signals,tumor markers and endometrial cancer[J].Horm Mol Biol Clin Investig,2015,21(1):89-106.
[26] Seldin MM,Peterson JM,Byerly MS,et al.Myonectin (CTRP15),a novel myokine that links skeletal muscle to systemic lipid homeostasis[J].BIOL CHEM,2012,287(15):11968-11980.
[27] Kong M,Gao Y,Guo X,et al.Role of the CTRP family in tumor development and progression[J].Oncol Lett,2021,22(4):723.
[28] Liao X,Liu S,Tang X,et al.Circulating CTRP6 levels are increased in overweight or obese Chinese individuals and associated with insulin resistance parameters:a pilot study[J].Exp Clin Endocrinol Diabetes,2021,129(7):535-541.
[29] Lei X,Seldin MM,Little HC,et al.C1q/TNF-related protein 6 (CTRP6) links obesity to adipose tissue inflammation and insulin resistance[J].Biol Chem,2017,292(36):14836-14850. |
2023, Vol. 29 
