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| Diagnostic Value of Fine Needle Aspiration Biopsy of Thyroid Nodules Guided by Conventional Ultrasound and Elastography for C-TI-RADS4 Nodules |
| DING Huajie, NA Lei, GONG Xue, et al |
| The Affiliated Hospital of Chengde Medical University, Hebei Chengde 067000, China |
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Abstract Objective: To investigate the diagnostic value of fine needle aspiration biopsy of thyroid nodules guided by conventional ultrasound and elastography for C-TI-RADS4 nodules.Methods:A total of 141 patients with 141 nodules who had undergone surgical resection of thyroid nodules from June 2019 to December 2021 at our hospital were retrospectively analyzed, and all nodules were classified as C-TI-RADS4. All nodules were subjected to conventional ultrasound and elastography strain-rate ratio-guided fine needle aspiration biopsy of the thyroid gland (US-FNAB, E-US-FNAB) to obtain cytopathological results, which were eventually compared with postoperative histopathological results to analyze the diagnostic value of conventional ultrasound and elastography-guided fine needle aspiration biopsy of thyroid nodules for C-TI-RADS4 category nodules.Results: For 141 C-TI-RADS4 category thyroid nodules, the sensitivity, specificity, accuracy, positive and negative predictive values of conventional ultrasound-guided fine-needle aspiration biopsy of thyroid nodules were 86.5%, 86.7%, 86.5%, 96%, and 63.4%, respectively; the sensitivity, specificity, accuracy, positive and negative predictive values of elastography-guided fine-needle aspiration biopsy of thyroid nodules were 96.4%, 86.7%, 94.3%, 96.4%, and 86.7%, respectively. The differences between the sensitivity, accuracy and negative predictive values were statistically significant (χ2=6.964, χ2=4.956, χ2=4.779, P<0.05); the differences between the specificity and positive predictive values of the two diagnoses were not statistically significant (χ2=0.000, χ2=0.000, P>0.05).Conclusion: Ultrasound elastography guided fine needle aspiration biopsy of thyroid nodule has certain clinical value in the diagnosis of C-TI-RADS4 nodule.
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[1] 鲁柯兵.超声引导下FNA联合BRAFV600E基因检测在甲状腺结节诊断中的意义[J].临床超声医学杂志,2019,3,21(3):215-217.
[2] 隋燕霞,蒋娜,南鹏飞,等.超声引导下FNAC联合BRAFV600E基因突变检测在甲状腺结节诊断中的意义[J].诊断病理学杂志,2020,27(1):31-37.
[3] 中华医学会-超声医学分会-浅表及血管组.2020甲状腺结节超声恶性分层中国指南:C-TIRADS[J].中华超声影像学杂志,2021,30(3):185-200.
[4] Zhou J,Yin L,Wei X,et al.2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules:the C-TIRADS[J].Endocrine,2020,70(2):256-279.
[5] 任玲,罗渝昆,宋青,等.高频超声对甲状腺无增强表现结节病理性质的诊断[J].中国医学影像学杂志,2020,28(3):174-177.
[6] 李春艳,李忠原.基于超声组学的甲状腺结节良恶性预测关键技术究[J].陕西医学杂志,2020,49(9):1134-1137.
[7] 杨丽娟,江波,郝艳敏,等.彩色多普勒超声联合超声弹性成像对甲状腺良恶性结节的鉴别诊断价值[J].河北医药,2020,42(9):1376-1378.
[8] 温悦,韩若凌.2018版国内甲状腺结节细针穿刺活检专家共识及相关国外指南解读[J].河北医科大学学报,2019,40(7):749-752.
[9] Sinha D,Sharma S,Kundaragi NG,et al.Added value of strain elastography in the characterisation of breast lesions:a prospective study[J].Ultrasound,2020,28(3):164-173.
[10] 任翠龙,刘晓华,谢怡,等.环状钙化超声影像在鉴别良恶性甲状腺结节中的应用[J].中国现代普通外科进展期刊,2020,23(4):308-312. |
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2023, Vol. 29 
