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| Relationship between Different Types of Dyslipidemia and Bone Mineral Density in Physical Examination Population in Changsha |
| ZHU Yemu, LI Cheng, Qin Jiao, et al |
| Changsha Central Hospital, Hunan Changsha 410000, China |
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Abstract Objective: To explore the relationship between different types of dyslipidemia and bone mineral density in physical examination population in Changsha. Methods: A retrospective analysis was performed on the related data of 527 objects undergoing physical examination in the hospital between May 2019 and May 2022. The basic data (blood lipid, bone mineral density) were collected. The objects with normal blood lipid, high triacylglycerol (TG), high cholesterol (TC) and mixed hyperlipidemia were included in normal group (n=140), high TG group (n=70), high TC group (n=159) and mixed group (n=158). The levels of blood lipid and bone mineral density among the four groups were compared. The correlation between blood lipid and bone mineral density, and the effects of blood lipid on bone mineral density were analyzed. Results: LDL-C level was the highest in high TC group, and low in normal group and high TG group. Except for normal group and high TG group, differences in LDL-C level among the other groups were statistically significant (P<0.05). TC in high TC group and mixed group was significantly higher than that in normal group and high TG group (P<0.05). HDL-C level was the highest in high TG group, and the lowest in mixed group (P<0.05). TG level was the highest in mixed group, and the lowest in normal group and high TC group. Except for normal group and high TC group, differences in TG level among the other groups were statistically significant (P<0.05). The ultrasonic velocity of right calcaneus in high TC group and mixed group were significantly lower than those in normal group and high TG group (P<0.05). The ultrasonic velocity of right calcaneus was negatively correlated with LDL-C, TC, HDL-C and TG (P<0.05). Multivariate linear regression analysis showed that influencing factors of bone mineral density were LDL-C, TC, TG and HDL-C. Conclusion: In physical examination population in Changsha, bone mineral density is lower in those with dyslipidemia. Especially, patients with TC and mixed dyslipidemia need regular screening of bone mineral density in order to detect bone mass changes early and conduct targeted preventive treatment.
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2023, Vol. 29 
