心电图最深S波QT间期离散度与原发性高血压合并左心室肥厚患者血压变异性NT-proBNP的相关性分析

doi:10.3969/j.issn.1006-6233.2022.12.029

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Abstract Objective: To analyze the correlation of the deepest S wave (SD) and QT (QTcd) interval dispersion of the electrocardiogram with blood pressure variability and NT-proBNP in patients with essential hypertension combined with left ventricular hypertrophy (LVH). Methods: A total of 304 patients with essential hypertension who were treated in the hospital from January 2021 to June 2022 were selected as the research subjects. According to whether the patients were accompanied by LVH or not, they were divided into LVH group (n=173) and non-LVH group (n=131). The SD, QTcd, blood pressure variability and serum NT-proBNP level were compared between the two groups, and the correlation between SD, QTcd and blood pressure variability and NT-proBNP in patients with essential hypertension and LVH was analyzed using Pearson correlation analysis. Results: SD and QTcd in LVH group were significantly higher than those in non-LVH group (P<0. 05). The 24h SCV, 24h DCV, dSCV, dDCV, nSCV and nDCV were significantly higher in LVH group than those in non-LVH group (P<0. 05). Serum NT-proBNP level in LVH group was significantly higher compared to non-LVH group (P<0. 05). SD and QTcd were significantly positively correlated with 24h SCV, 24h DCV, dSCV, dDCV, nSCV and nDCV in patients with essential hypertension and LVH (P<0. 05). SD and QTcd were significantly positively correlated with NT-proBNP in patients with essential hypertension complicated with LVH (P<0. 05). Conclusion: SD and QTcd in patients with essential hypertension complicated with LVH are significantly increased, which may be related to blood pressure variability and serum NT-proBNP level.

Key words： Essential hypertension Left ventricular hypertrophy Electrocardiogram deepest S wave QT interval dispersion Blood pressure variability N-terminal pro-B-type natriuretic peptide

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2022.12.029 OR http://www.hbyxzzs.cn/EN/Y2022/V28/I12/2086

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