|
|
Clinical Effect of Focused Ultrasound in the Treatment of vulvar sclerosing moss |
WANG Xiaowei, et al |
Chengde Maternal and Child Health Hospital, Hebei Chengde 067000, China |
|
|
Abstract Objective: To analyze the clinical effect of focused ultrasound in patients with vulvar sclerosing moss. Methods: 76 patients with vulvar sclerosing moss who were admitted and treated from July 2019 to June 2020 were randomly divided into the study group and the control group, 38 patients in each group. The control group received testosterone propionate injection, and the study group received focused ultrasound treatment (once every 7-10 days, 6 consecutive times). The efficacy, pruritus degree and recurrence rate of the two groups were compared, and the SF-36 quality of life questionnaire was selected to evaluate the health status of the two groups. Results: Comparing the two groups, the total effective rate of treatment in the research group is higher, with statistical significance (97. 37% vs 78. 95% χ2=6. 176 P=0. 013); the recurrence rate was decreased, with statistical significance (2. 63% vs 18. 42%) χ2=5. 029 P=0. 025). The itching degree score and SF-36 score of the research group before treatment had no statistical significance (2. 72±0. 25 points vs 2. 70±0. 24 points t=0. 356 P=0. 723, 650. 33±26. 71 points vs 651. 71± 27. 42 points t=0. 222 P=0. 825); the pruritus degree scores of the research group after 1 month, 3 months and 6 months of treatment were all decreased, with statistical significance (2. 26±0. 26 points vs 2. 51±0. 25 points t=4. 273 P =0. 001, 1. 69±0. 28 points vs 2. 18±0. 35 points t=6. 739 P=0. 001, 1. 07±0. 31 points vs 1. 82±0. 35 points t=9. 888 P=0. 001), 1 month, 3 months, 6 months of treatment The SF-36 scores of the research group were all increased, with statistical significance (675. 62±24. 46 points vs 662. 51±25. 22 points t=2. 300 P=0. 024, 692. 65±22. 68 points vs 678. 41±22. 53 points t=2. 746 P=0. 008, 727. 91±21. 52 vs 701. 45±20. 49 points t=5. 489 P=0. 001). Conclusion: Focused ultrasound therapy for patients with vulvar sclerosing moss can significantly relieve itching symptoms, and the recurrence rate after treatment is low, which is conducive to improving the quality of life of patients.
|
|
|
|
|
[1] 杨丽云,成乐楠,卢晓莉,等.5-氨基酮戊酸光动力疗法治疗外阴硬化性苔藓的临床研究[J].宁夏医学杂志,2021,43(7):642-644. [2] 朱利红,赵淑珍,王玉红,等.女性外阴硬化性苔藓患者血清性激素水平与疾病严重程度的相关性分析[J].皮肤性病诊疗学杂志,2019,26(1):23-27. [3] 李晓丹,安芳,王晓瑞,等.高强度聚焦超声消融治疗子宫肌瘤的临床效果及对妊娠结局的影响[J].内蒙古医学杂志,2021,53(10):1240-1241,1244. [4] Angelova-Fischer I,Bauer A,Hipler U C,et al.The objective severity assessment of atopic dermatitis (OSAAD) score:validity,reliability and sensitivity in adult patients with atopic dermatitis.[J].The British journal of dermatology,2005,153(4):67-73. [5] 孙松朋,龙俊红,张书信.中文版SF-36量表应用于肛肠良性疾病患者生命质量评价的信度和效度研究[J].结直肠肛门外科,2019,25(5):497-505,512. [6] 中国医疗保健国际交流促进会妇儿医疗保健分会外阴阴道疾病项目专家委员会.女性外阴硬化性苔藓临床诊治专家共识(2021年版)[J].中国实用妇科与产科杂志,2021,37(1):70-74. [7] 李昕雨,吕亚婷,郭淑兰,等.硬化性苔藓64例临床及病理学特征分析[J].中国麻风皮肤病杂志,2022,38(7):442-446. [8] 刘瑶,范艺巾,秦溢,等.聚焦超声抑制慢性单纯性苔藓大鼠外阴皮肤纤维化及其机制研究[J].临床超声医学杂志,2020,22(8):561-565. [9] 陶春霞,肖菊花,曾莹,等.超声聚焦技术治疗外阴上皮内非瘤样病变的临床研究[J].江西医药,2018,53(10):1115-1116. |
|
|
|