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| Association of Triglyceride to High-Density Lipoprotein Cholesterol Ratio with Metabolic Syndrome in High-risk Diabetic Population |
| HOU Yilin, et al |
| Graduate School of Hebei Medical University, Hebei Shijiazhuang 050017, China |
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Abstract Objective: To investigate the correlation between triglycerides to high-density lipoprotein cholesterol ratio (TG/HDL-C) and metabolic syndrome (Mets) in high-risk diabetic population. Methods: According to the definition of high-risk groups of type 2 diabetes in China's Guidelines for the Prevention and Treatment of Type 2 Diabetes (2017 Edition), patients were recruited from the outpatient of the Department of Endocrinology of Hebei General Hospital from April 2018 to April 2019. A total of 531 patients participated in the study. A multivariate Logistic regression model was used to assess their correlation between TG/HDL-C and Mets. Results: TG/HDL-C of the patients with Mets was significantly higher than those without Mets [1.73(1.03,2.55) vs 0.76(0.54,1.12), P<0.001]. With the increase of TG/HDL-C, the prevalence of Mets gradually increased (P<0.001). TG/HDL-C was an independent influencing factor of Mets. After correcting the relevant influencing factors, TG/HDL-C was positively correlated with Mets(Odds ratios=5.23, 95% Confidential interval: 3.30-8.29, P<0.001). Conclusion: TG/HDL-C is closely related to Mets in high-risk groups with type 2 diabetes mellitus, and with the increase of TG/HDL-C, the risk of Mets is significantly increased.
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2022, Vol. 28 
