|
|
Effect of Group B Haemolytic Streptococci on Maternal Coagulation Vaginal Microecology and Pregnancy Outcome |
GUO Haihong, et al |
Fenyang Hospital, Shanxi Fenyang 032200, China |
|
|
Abstract Objective: To investigate the effect of group B hemolytic streptococcus (GBS) on maternal blood coagulation, vaginal microecology and pregnancy outcome. Methods: A total of 210 pregnant women with GBS infection who were admitted to our hospital from January 2020 to February 2022 were selected as the research subjects, and 210 pregnant women with normal obstetric examination during the same period were selected as the control group. The coagulation function, vaginal microecology and pregnancy outcomes of the two groups of pregnant women were compared. and the association of GBS with coagulation function, vaginal microecology and pregnancy outcome was analyzed. Results: Patients in the study group had significantly lower AP, APTT and INR levels than the control group and significantly higher Fbg levels than the control group (P<0.05).The difference between the two groups was not statistically significant (P>0.05) when comparing positive Trichomonas vaginalis, but the rate of vaginal micro-ecological disorders, positive fungi, positive bacterial vaginosis, abnormal pH, and abnormal cleanliness was higher in the study group than in the control group, which was statistically significant (P<0.05). The incidence of caesarean section, premature rupture of membranes, puerperal infection, intrauterine infection, prematurity, pathological jaundice, neonatal infection and neonatal asphyxia was significantly higher in the study group than in the control group (P<0.05). Conclusion: Pregnant women with Group B haemolytic streptococcal (GBS) infection during pregnancy are at risk of blood hypercoagulation, vaginal microecological disorders and adverse pregnancy outcomes. Maintaining stable vaginal microecology, focusing on coagulation testing and early management can help to reduce the risk of adverse pregnancy outcomes.
|
|
|
|
|
[1] 高艳杰,龚春桃,汪海霞,等.血清β-HCG PCT CRP及分泌物GBS联合检查在预测胎膜早破孕妇并发绒毛膜羊膜炎及新生儿感染的临床价值[J].河北医学,2021,27(6):930-934. [2] 刘利,高玲玲,周冰侠.孕晚期B族溶血性链球菌感染的危险因素分析[J].实用临床医药杂志,2021,25(14):37-40. [3] 陈春,李彩霞.汉中地区孕妇妊娠晚期B族溶血性链球菌感染率及其对母儿的影响[J].陕西医学杂志,2018,47(11):44-47. [4] 张艺,杜晨旭,张适,等.B族溶血性链球菌与围生期妇女妊娠结局的相关性分析[J].中国卫生检验杂志,2019,29(22):2757-2758,2761. [5] 胡哲,杨曼曼.土家药鸡血七不同萃取部分PT、APTT、TT的检测[J].西部中医药,2019,32(3):26-28. [6] 余清源.妊娠晚期孕妇B族溶血性链球菌感染对孕产妇母婴结局及凝血功能的影响[J].血栓与止血学,2020,26(1):82-83. [7] 章春凤,朱庭舫.乳酸菌阴道胶囊治疗老年性阴道炎的效果分析[J].中国基层医药,2019,26(7):822-825. [8] 盛群英,林雅真,崔晓洁,等.细菌16S rDNA测序分析妊娠晚期孕妇感染B族链球菌对阴道微生态及母婴结局的影响[J].国际检验医学杂志,2020,41(20):2528-2532. |
|
|
|