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| The Value of Ambulatory Blood Pressure Combined with Quantitative 24-Hour Urine Protein Monitoring in Pre-Eclampsia and Its Pregnancy Outcome |
| YE Ping, CHEN Hongbo, HUANG Xiangyan, et al |
| Maternal and Child Health Hospital Affiliated to Anhui Medical University, Anhui Maternal and Child Health Hospital, Anhui Hefei 230000, China |
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Abstract Objective: To investigate the value of ambulatory blood pressure combined with quantitative 24-hour urine protein monitoring in pre-eclampsia and its pregnancy outcome. Methods: From January 2019 to December 2020, 78 cases of pregnant women with pre-eclampsia were selected for the study. The patients were divided into 32 cases in the observation group with adverse pregnancy outcomes and 46 cases in the control group without adverse pregnancy outcomes according to whether the mothers and infants had adverse pregnancy outcomes. 24-hour ambulatory blood pressure monitoring and quantitative urine protein analysis were performed respectively. Results: The dSBP, dDBP, nSBP and 24hDBP were all higher in the observation group than in the control group (P<0.05); the final birth weight (FBW) of the children in the observation group was significantly lower than that of the control group (t=6.261, P<0.001); the 24-hour urine protein quantification was significantly higher in the observation group than in the control group (t=2.986, P<0.001); all patients in the observation and control groups had significantly higher SBP blood pressure load values and DBP blood pressure load values at night than during the day (P<0.001). Conclusion: Patients with pre-eclampsia have a high incidence of abnormal circadian rhythms, characterized by non-arrythmic circadian rhythms and elevated blood pressure at night, and ambulatory blood pressure and proteinuria monitoring can indicate adverse pregnancy outcomes.
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2022, Vol. 28 
