药物涂层球囊扩张与经皮腔内球囊扩张合并支架植入术对下肢动脉硬化闭塞病变患者治疗的各项临床指标的影响

doi:10.3969/j.issn.1006-6233.2022.06.018

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Abstract Objective: To study the effect of drug-coated balloon dilation (DCB) and percutaneous intraluminal balloon dilation combined with stent implantation in the treatment of lower extremity arteriosclerosis occlusive lesions (LEAOD). Methods: A retrospective analysis was performed on 88 patients with LEAOD admitted from March 2017 to February 2022, who were divided into study group (44 cases) and control group (44 cases) according to different treatment methods. The study group was treated with DCB and remedial stenting if necessary; the control group was treated with percutaneous intracavitary balloon dilation combined with stenting. The clinical indicators of "late lumen loss (LLL) value, degree of lower limb artery stenosis, minimum lumen diameter of lower limb artery (MLD), ankle-brachial index (ABI)" and postoperative recovery (incidence of malignant events, revascularization rate of target lesion vessels, restenosis rate, Rutherford grade) were compared between the two groups. Results: The difference in ABI between the two groups on the first day after surgery was not statistically significant (P>0.05); the ABI at 3 months after surgery was higher than that on the first day after surgery in both groups, and the difference was higher in the study group at 3 months after surgery compared with the control group (P<0.05). The differences in LLL values, lower limb artery stenosis and MLD on the first day after surgery were not statistically significant between the two groups (P>0.05); LLL values, lower limb artery stenosis and MLD at 3 months after surgery were lower than on the first day after surgery in both groups, and LLL values and lower limb artery stenosis were lower and lower limb artery MLD was higher in the study group than in the control group at 3 months after surgery, and the differences were statistically significant (P<0.05). The LLL values, lower limb artery stenosis and MLD at 3 months after surgery were lower than those at the first postoperative day in both groups, and the LLL values and lower limb artery stenosis at 3 months after surgery were lower and the lower limb artery MLD was higher in the study group than in the control group, and the differences were statistically significant (P<0.05). There was no statistically significant difference in the incidence of malignant events between the two groups at 3 months postoperatively (P>0.05); the rate of revascularisation of the target lesion, the rate of restenosis and the rate of uterford classification ≤3 were lower in the study group at 3 months postoperatively, all with statistically significant differences (P<0.05). Conclusion: DCB has been shown to be effective in the treatment of LEAOD, further improving arterial stenosis, raising ABI values, accelerating restoration of lower limb arterial flow and reducing restenosis and malignant events

Key words： Lower limb arteriosclerosis occlusive lesions Stent implantation Percutaneous intraluminal balloon dilation Dilation of drug-coated balloon Lower extremity artery stenosis

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	ZHANG Kaixin
	ZHANG Ming
	CHEN Jun
	et al

Cite this article:

ZHANG Kaixin,ZHANG Ming,CHEN Jun, et al. Effects of Drugcoated Balloon Dilation and Percutaneous Intraluminal Balloon Dilation Combined with Stent Implantation on Clinical Indexes of Patients with Lower Extremity Arteriosclerosis Occlusive Lesions[J]. HeBei Med, 2022, 28(6): 960-963.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2022.06.018 OR http://www.hbyxzzs.cn/EN/Y2022/V28/I6/960

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