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| Predictive Value of Blood Flow Indicators of Middle Cerebral Artery Combined with Ductus Venosus on Fetal Intrauterine Hypoxia in Gestational Diabetes Mellitus |
| KE Fengmei, SU Ruifen, SHUI Chengyu, et al |
| The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Hubei Enshi 445000, China |
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Abstract Objective: To investigate the predictive value of blood flow indicators of middle cerebral artery (MCA) combined with ductus venosus (DV) on fetal intrauterine hypoxia in gestational diabetes mellitus (GDM). Methods: 48 GDM pregnant women with fetal intrauterine hypoxia who were treated and delivered in our hospital between July 2019 and July 2020 were selected as the case group, and 48 normal singleton pregnant women were selected as the control group. Color Doppler ultrasound was applied to detect the fetal MCA and DV blood flow indicators in the two groups of fetuses, including resistance index (RI), pulsatility index (PI) and peak systolic velocity/end diastolic velocity (S/D), and comparative analysis was conducted. Results:Compared with the control group, the RI, PI and S/D values of MCA in the case group were significantly decreased (P<0.05), the RI, PI and S/D values of DV were significantly increased (P<0.05), and the RIMCA/RIDV, PIMCA/PIDV and (S/D) MCA/(S/D)DV were also significantly decreased (P<0.05). Logistic regression analysis showed that the ratios of RIMCA/RIDV, PIMCA/PIDV and (S/D) MCA/(S/D)DV were 1.385, 1.602 and 1.480 respectively, which were independent predictors of fetal intrauterine hypoxia in GDM (P<0.05). ROC curve analysis showed that the areas under the curves of RIMCA/RIDV, PIMCA/PIDV, (S/D)MCA/(S/D)DV and the combination of the three in predicting fetal intrauterine hypoxia in GDM were 0.869, 0.870, 0.897 and 0.975 respectively, and the predictive value of the combination of the three was the largest. Conclusion: MCA combined with DV blood flow indicators have important reference value in predicting fetal intrauterine hypoxia in GDM.
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2021, Vol. 27 
