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| The Predictive Value of CK AFP and β-hCG in Maternal Serum for Placental Implantation |
| QIU Xiaoru, LIU Xiaohua, WU Xinxin, et al |
| Chengde Central Hospital, Hebei Chengde 067000, China |
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Abstract Objective: Based on the levels of CK, AFP and β-hCG in the maternal serum, the value of predicting placenta accreta was explored. Methods: 50 cases of puerpera in the obstetrics department of Chengde Central Hospital from 2017 to 2019 who were pathologically diagnosed as placenta accreta were selected as the experimental group. 52 cases of non-placental implant women were randomly selected as the control group. The maternal serum CK, AFP and β-hCG levels were measured in each group, and the datas were analyzed by spss23.0 statistical software. Results: The levels of the three types of indicators in the experimental group were significantly higher than those in the control group. The datas were compared and the differences were statistically significant; and the three types of indicators had a certain predictive value for placental accreta, and the combination of the three indicators has higher predictive value for placenta accreta, with sensitivity and specificity of 70% and 81% respectively.The cut off values of serum CK, AFP and β-hCG for placenta accreta is 153.14U/mL, 193.23U/mL and 21909U/L. Conclusion: The combination of CK,AFP and β-hCG in maternal serum can effectively predict the placental accreta of pregnant women before delivery, and the predictive value is relatively high.
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2021, Vol. 27 
