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Effect of Hemodialysis Combined with Hemodiafiltration and Hemoperfusion on Renal Anemia in Patients |
MIAO Changxian, BAO Pin, YAN Xiaolu, et al |
Dalian Third People's Hospital, Liaoning Dalian 116033, China |
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Abstract Objective: To explore the effect of hemodialysis combined with hemodiafiltration and hemoperfusion on renal anemia in patients. Methods: 100 patients who underwent maintenance hemodialysis in our hospital from August 2018 to April 2020 were selected. According to the simple random number method, they were divided into group A (hemodialysis combined with hemodiafiltration) and group B (hemodialysis combined with hemoperfusion), with 50 cases in each group. The renal anemia indicators [hemoglobin (Hb), hematocrit (Hct), reticulocyte percentage (Ret), serum iron] and blood calcium, blood phosphorus and parathyroid hormone (iPTH) were compared between the two groups before and after treatment, and the incidence rate of adverse events was counted in the two groups. Results: After treatment, Hb, Hct, Ret and serum iron were significantly higher than those in group A (P<0.05). After treatment, the blood calcium level in group B was significantly higher than that in group A while the levels of blood phosphorus and iPTH were significantly lower than those in group A (P<0.05). The incidence rate of adverse reactions in group B was significantly lower than that in group A (P<0.05). Conclusion: Compared with hemodialysis combined with hemodiafiltration can more effectively correct renal anemia, reduce iPTH level and improve calcium and phosphorus metabolism in patients with maintenance hemodialysis.
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