精神分裂症患者攻击行为与血浆IL-6 IL-10 血清甲状腺激素水平关系

doi:10.3969/j.issn.1006-6233.2021.04.04

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Abstract Objective: To explore the relationship between aggressive behavior and plasma IL-6, IL-10 and serum thyroid hormone levels in patients with schizophrenia.Methods: The clinical data of 118 patients with schizophrenia admitted to our hospital from February 2018 to February 2020 were analyzed. According to their MOAS scores, they were divided into 51 cases of aggressive behavior (group A) and 66 cases of non-aggressive behavior (group B) ), measure the levels of IL-6, IL-10 and thyroid hormone (T3, T4, TSH) in all patients and compare them between groups. Use Spearman to analyze the correlation between each index and aggressive behavior in patients with schizophrenia. Results: The scores of the MOAS scale in group A were higher than those in group B (P<0.05); the IL-6 index of group A was higher than that of group B (P>0.05), and the IL-10 index was lower than group B (P<0.05) ; Thyroid hormones (T3, T4, P>0.05; TSH, P<0.05) in group A were higher than those in group B; Aggressive behavior in schizophrenia patients was correlated with IL-6 (r=0.309), IL-10 (r =0.523) significantly correlated (P<0.05); Aggressive behavior T3 (r=0.540) and T4 (r=0.605, P<0.05) are significantly correlated with TSH (r=0.214) , (P>0.05). The correlation is not significant. Conclusion: Plasma IL-6, IL-10 and serum thyroid hormone T3 and T4 indicators are significantly correlated with aggressive behavior in patients with schizophrenia. In the future, more attention should be paid to these indicators in order to provide patients with better quality diagnostic and prognostic services.

Key words： Schizophrenia Interleukin-6 Interleukin-10 Thyroid hormone Aggressive behavior

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	DAI Jinglan
	HE Jinquan
	LUO Jun
	et al

Cite this article:

DAI Jinglan,HE Jinquan,LUO Jun, et al. Relationship between Aggressive Behavior and Plasma IL-6 IL-10 and Serum Thyroid Hormone Levels in Patients with Schizophrenia[J]. HeBei Med, 2021, 27(4): 542-546.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2021.04.04 OR http://www.hbyxzzs.cn/EN/Y2021/V27/I4/542

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