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| Analysis of Incidence and Risk Factors of Adverse HT and Prognosis in Patients with Acute Cerebral Infarction After Mechanical Thrombolysis |
| XU Hui, et al |
| Fuyang People's Hospital, Anhui Fuyang 236000, China |
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Abstract Objective: To analyze the occurrence and risk factors of hemorrhagic transformation (HT) and poor outcome in patients with acute cerebral infarction after mechanical thrombectomy. Methods: The clinical data of 80 patients with acute cerebral infarction admitted to our hospital from January 2019 to January 2020 were retrospectively analyzed. The modified Rankin Scale (mRS) was used to evaluate the clinical outcome of the patients 90 days after the onset of the disease. According to the occurrence of HT,they were divided into HT group and non-HT group; according to mRS score,they were divided into good outcome group and poor outcome group. Multivariate logistic regression analysis was used to analyze the independent risk factors that affect patients' poor outcome and HT. Results: The gender,history of diabetes,history of atrial fibrillation,fasting blood glucose,time from puncture to recanalization,number of thrombectomy,mTICI grade after thrombectomy were compared between the HT group and the non-HT group with statistically significant differences (P<0.05). Using the above factors as independent variables and HT as the dependent variable for multivariate logistic regression analysis,the results showed that atrial fibrillation,the time from puncture to recanalization,the number of thrombectomy times,and the mTICI grade after thrombectomy were the independent risk factors for HT after embolization (P<0.05) that led to mechanical retrieval in patients with acute cerebral infarction. Patients in the good outcome group and the poor outcome group have history of diabetes,atrial fibrillation,baseline National Institutes of Health Stroke Scale (NIHSS) score,middle cerebral artery occlusion vessel,vertebrobasilar artery occlusion vessel,anterior circulation stroke,HT and brain The comparison of parenchymal hematoma was statistically significant (P<0.05). Multivariate logistic regression analysis with the above factors as independent variables and poor outcome as the dependent variable showed that diabetes,baseline NIHSS score,and cerebral parenchymal hematoma were all independent factors that caused poor outcomes in patients with acute cerebral infarction after mechanical thrombectomy (P<0.05). Conclusion: Complicated brain parenchymal hematoma,high baseline NIHSS score,and diabetes are independent risk factors for adverse outcomes in patients with acute cerebral infarction after mechanical thrombectomy,while atrial fibrillation is an independent risk factor for HT.
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2021, Vol. 27 
