|
|
|
| Effects of Pterygium Excision Combined with Superior Temporal Limbal Stem Cell Transplantation on Postoperative Corneal Astigmatism in Pterygium Patients |
| YANG Junchen, CHENG Tingyu, CHENG Yinong, et al |
| ThePeople's Hospital of Huangshan City, Anhui Huangshan 245000, China |
|
|
|
|
Abstract Objective: To study the efficacy of pterygium excision combined with superior temporal limbal stem cell transplantation in the treatment of pterygium. Methods: A total of 60 pterygium patients admitted to hospital from January 2019 to January 2020 were divided into two groups according to the random number table method, one group was the control group, According to the simple random grouping method, they were randomly divided into two groups (study group and control group with 30 cases each). The control group was treated with pterygium excision alone, while the study group was treated with pterygium excision combined with superior temporal limbal stem cell transplantation. Before and after operation, corneal astigmata, naked eye vision, postoperative corneal wound healing time, total effective rate, complication rate and recurrence rate were compared between the two groups. Results: there was no difference in preoperative corneal astigmatism and naked eye vision between the two groups (P>0.05). The postoperative corneal astigmatism of the two groups was lower than that of the preoperative, and the visual acuity of the naked eye was higher (P<0.05). Compared with the control group, the study group had lower postoperative keratodispersion and recurrence rates, higher naked eye vision and total effective rate, and shorter corneal wound healing time (P<0.05). There was no difference in postoperative complication rate between the two groups (P>0.05). Conclusion: Pterygium excision combined with superior temporal limbal corneal dry cell transplantation is effective in the treatment of pterygium patients, which can effectively reduce the patients' corneal astigmata, improve the level of naked eye vision, and promote the rapid healing of corneal wound, with low complication rate and recurrence rate.
|
|
|
|
|
|
[1] 雷新建.翼状胬肉切除联合角膜缘干细胞移植术与单纯翼状胬肉切除术对翼状胬肉患者治愈与复发及术后恢复的影响观察[J].贵州医药,2020,44(4):613~615.
[2] 吴三妹.翼状胬肉切除术联合自体角膜缘干细胞移植术治疗翼状胬肉患者的临床效果[J].医疗装备,2020,33(7):88~89.
[3] 章宜怡,宋力,仓定红,等.自体角膜缘干细胞移植与单纯切除术对33例翼状胬肉患者视觉质量及并发症的影响[J].上海医药,2019,40(23):55~57.
[4] 凌雪云.翼状胬肉切除术联合自体角膜缘干细胞移植术治疗翼状胬肉的效果研究[J].当代医药论丛,2019,17(21):86~87.
[5] Oner V,Tas M,Qzkaya E,et al.Influence of pterygium on corneal biomechanical properties[J].Curr Eye Res,2016,41(7):913~916
[6] Monden Y,Nagashima C,Yokote N,et al. Management of recurrent pterygium with severe symblepharon using mitomycin C,double amniotic membrane transplantation,cryopreserved limbal allograft,and a conjunctival flap.[J]. International medical case reports journal,2020,13(27):145~147.
[7] 杨迪康,曾颖.翼状胬肉切除联合自体角膜缘干细胞移植术的临床分析[J].当代医学,2019,25(15):169~171.
[8] 宣瑾,杨慧英.翼状胬肉切除联合角膜缘干细胞移植术的临床分析[J].中国医药科学,2018,8(23):242~244.
[9] 黄慕贞.翼状胬肉切除联合自体角膜缘干细胞移植术治疗翼状胬肉的临床疗效[J].黑龙江医学,2018,42(11):1064~1065. |
|
|
|
2021, Vol. 27 
