反复种植失败患者子宫动脉血流动力学和血栓弹力图参数分析

doi:10.3969/j.issn.1006-6233.2021.02.002

Abstract
Figure/Table
References
Related Citation (1)

Download: PDF (1323 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective: To explore the relationship between uterine artery hemodynamic parameters and coagulation function in patients with repeated implantation failure. Methods: The patients undergoing in vitro fertilization-embryo transfor (IVF-ET) treatment in our hospital were divided into the first pregnancy success group, the first pregnancy failure group and the repeated implantation failure group. The basic data, oocyte acquisition, transplantation, uterine artery hemodynamics and thromboelastogram parameters were collected and analyzed. Results: There were no statistically significant difference in the basic data, oocyte acquisition and transplantation of the three groups; the uterine artery hemodynamic parameters PI, RI and S/D in the repeated failure group were higher than those in the other two groups, and the difference were statistically significant; The MA value of the repeated failure group were significantly higher than those in the other two groups. Conclusion: It is very necessary to detect the uterine artery hemodynamic parameters and TEG in patients who were suspected with repeated implantation failure. Once the prethrombotic state or the increase of uterine artery blood flow resistance was found, corresponding treatment should be given in time to improve the success rate.

Key words： Recurrent implantation failure Thromboelastogram parameter Uterine artery hemodynamic Prethrombotic state

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2021.02.002 OR http://www.hbyxzzs.cn/EN/Y2021/V27/I2/181

[1] Ziya Kalem,Muberra Namli Kalem,Batuhan Bakirarar,et al. Intrauterine G-CSF administration in recurrent implantation failure (RIF)[J]. Sci Rep,2020,10(1):5139.
[2] Yuye Li,Shuyi Yu,Chunyu Huang,et al. Evaluation of peripheral and uterine immune status of chronic endometritis in patients with recurrent reproductive failure [J] Fertil Steril,2020,113(1):187~196.
[3] Kliman HJ,Frankfurter D. Clinical approach to recurrent implantation failure:evidence-based evaluation of the endometrium[J].Fertil Steril,2019,111(4):618~628.
[4] 罗丝丝,高明霞,曹冲,等.反复种植失败患者冻融胚胎移植周期中推后种植窗对妊娠结局的影响[J].兰州大学学报(医学版),2019,45(4):5~9.
[5] Wen Yang,Ze Wu,Ming Yu,et al. Characteristics of midluteal phase uterine artery hemodynamics in patients with recurrent pregnancy loss [J].Obstet Gynaecol Res,2019,45(7):1230~1235.
[6] Martinez-Zamora MA,Tassies D,Reverter JC,et al. Increased circulating cell-derived microparticle count is associated with recurrent implantation failure after IVF and embryo transfer [J]. Reprod Biomed Online,2016,33(2):168~173.
[7] 于鹏跃,赵凤莲,张晓华,等.血栓弹力图、平均血小板体积/血小板计数比值和纤维蛋白原水平对复发性流产的预测价值[J].吉林大学学报(医学版),2020,46(1):127~131.
[8] 梁荣丽,罗宋.低分子肝素联合小剂量阿司匹林对原因不明复发性流产患者血栓前状态及免疫功能的影响[J].中国计划生育学杂志,2019,27(2):184~188.
[9] Lambert M,Hocke C,Jimenez C,et al. Repeated in vitro fertilization failure:abnormalities identified in the diagnostic assessment [J]. Gynecol Obstet Fertil,2016,44(10):565~571.
[10] Villani M,Baldini D,Totaro P,et al. Rationale and design of two prospective multicenter observational studies on reproductive outcome in women with recurrent failures after spontaneous or assisted conception:OTTILIA and FIRST registries [J]. BMC Pregnancy Childbirth,2019,19(1):292.
[11] Djurovic J,Stojkovic O,Todorovic J,et al. Genetics of suspected thrombophilia in serbian females with infertility,including three cases,homozygous for FII 20210A or FV 1691A mutations [J]. Hum Fertil (Camb),2017,20(2):132~139.