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| An Analysis of Clinical Characteristics and Risk Factors of Gastroesophageal Reflux Disease Manifested by Extraesophageal Symptoms Among Elderly Patients |
| BU Guangkui, LIAO Jiangtao |
| Hunan Provincial People's Hospital / First Affiliated Hospital of Hunan Normal University, Hunan Changsha 410016, China |
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Abstract Obejective: To explore the clinical characteristics and risk factors of elderly patients with gastroesophageal reflux disease manifested by extraesophageal symptoms. Methods: The clinical data of elderly GERD patients in our hospital from January 2016 to January 2020 were retrospectively analyzed, and the patients were divided into extra-esophageal symptoms group and non-esophageal symptoms group according to whether extra-esophageal symptoms occurred, analyze the clinical characteristics and risk factors of patients with extraesophageal symptoms. Results: The incidence of extraesophageal symptoms in elderly GERD patients is about 52.59%, throat foreign body sensation, chronic cough, and reflux pharyngitis are most common, accounting for 31.97%, 24.59%, and 18.85%, respectively. There were significant differences between the two groups of patients in COPD, calcium channel antagonists, anxiety and depression, sleep disorders, constipation, gastroscopy reflux esophagitis, hiatal hernia, and BMI (P <0.05). Multiple logistic regression analysis revealed anxiety and depression (OR: 3.891, 95% CI: 1.254 to 5.169, P <0.001), hiatal hernia (OR: 4.114, 95% CI: 2.013 to 6.242, P <0.001), BMI (OR: 3.457, 95% CI: 2.287 ~ 4.728, P = 0.001), and smoking (OR: 2.782, 95% CI: 1.651 ~ 3.907, P = 0.009) were risk factors for extraesophageal symptoms in elderly GERD patients. Conclusion: The most common manifestations of extraesophageal symptoms in elderly GERD patients are foreign body sensation in the throat, chronic cough, and reflux pharyngitis. Anxiety and depression, hiatal hernia, BMI, and smoking are risk factors for extraesophageal symptoms in elderly GERD patients.
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2021, Vol. 27 
