妊娠期糖尿病与血清铁铁蛋白以及转铁蛋白的相关性

doi:10.3969/j.issn.1006-6233.2020.12.039

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Abstract Objective: To explore the relationship between gestational diabetes and serum iron, ferritin and transferrin. Methods: The data of pregnant women in the second trimester of pregnancy (24 weeks to 28 weeks of pregnancy) who were admitted to the Affiliated Hospital of Chengde Medical College from May 2018 to January 2020 were selected for retrospective analysis. According to the diagnosis results of all pregnant women, they were divided into GDM group (n=127) and normal group (n=130). Compare the general clinical data of the two groups of pregnant women. Compare the blood-related indicators [hemoglobin (Hb), mean red blood cell volume (MCV), mean red blood cell hemoglobin content (MCH), mean red blood cell hemoglobin concentration (MCHC)], blood glucose indicators [fasting blood sugar, blood sugar 1h blood sugar, serving Sugar 2h blood glucose], iron-related indicators [serum iron (SI), serum ferritin (SF), serum transferrin (TRF)]. Analysis of the correlation between iron related indicators and fasting blood glucose was conducted. Analysis of independent factors of GDM was conducted. Results: The data of sex, age, BMI and gestational age in GDM group and normal group were not statistically significant (P>0.05). The fasting blood glucose, blood glucose for 1h, glucose for 2h, SI, SF, TRF in the GDM group were higher than those in the normal group (P<0.05). The difference in Hb, MCV, MCH, MCHC data between the two groups was not statistically significant (P>0.05). There was a positive correlation between SI, SF, TRF and fasting blood glucose (P<0.05). SI, SF, TRF have become independent factors of GDM (P<0.05). Conclusion: Patients with GDM are prone to increased iron storage. The increase in SI, SF, and TRF has a certain correlation with the incidence of GDM. In actual work, more attention is needed.

Key words： Gestational diabetes mellitus Serum iron Ferritin Transferrin Blood glucose

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2020.12.039 OR http://www.hbyxzzs.cn/EN/Y2020/V26/I12/2098

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