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| Value of High-Frequency Ultrasound of Wrist and Finger Joint in the Diagnosis and Differential Diagnosis of Rheumatoid Arthritis |
| ZHANG Ying, MENG Jinghong, XIE Jianli, et al |
| The Third Hospital of Hebei Medical University,Hebei Shijiazhuang 050051,China |
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Abstract Objective: To investigate the value of high-frequency ultrasound (HFUS) of wrist and finger joint in the diagnosis and differential diagnosis of rheumatoid arthritis (RA) and hand osteoarthritis(OA).And to analyze the value of semi-quantitative ultrasound score in the assessment of disease activity of RA.Methods: 54 patients with RA were enrolled,and 30 patients with hand OA were selected as control group.Wrist joints,metacarpophalangeal and proximal interphalangeal joints were examined by high-frequency ultrasound.The thickness of synovial membranes,synovial blood flow,bone erosion and tenosynovitis were measured.Semi-quantitative ultrasound scores of the above four indexes were calculated.And laboratory characteristics were carefully recorded,including ESR,CRP,RF,anti-CCP and DAS28 scores in the RA group.The correlation between ultrasound scores and clinical indicators were analyzed.Results: RA group was significantly more than OA group with synovial hyperplasia,synovial blood flow,bone erosion and tenosynovitis (P<0.01).There were significant positive correlation between semi-quantitative ultrasound score and DAS28 score (r=0.550,P<0.05).Conclusion: High-frequency ultrasound was valuable in the diagnosis and differential diagnosis of RA and hand OA.Semi-quantitative ultrasound score can reflect the disease activity in RA.
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2020, Vol. 26 
