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| The Comparison of Curative Efficacy of Different Anesthesia Methods in Radical Gastrectomy and the Effects on Liver and Kidney Function and Oxygenation Function |
| ZHAO Jianli, HUANG Hongmei, et al |
| Baise People's Hospital, Guangxi Baise 533000, China |
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Abstract Objective: To study the curative efficacy of different anesthesia methods radical gastrectomy and the effects on liver and kidney function and oxygenation function.Methods: 100 patients admitted to our hospital for radical gastrectomy from August 2016 to August 2019 were included in this study and divided into the observation group (n=53) and the control group (n=47) with simple random grouping method.The control group received general anesthesia, and the observation group received epidural block combined with general anesthesia.The two groups were compared with postoperative clinical indicators, cereal third transaminase (ALT), aspertate aminotransferase (AST), total bilirubin (TBIL), urine nitrogen (BUN), serum creatinine (Cr), pulmonary blood FenLiuLv (QS/QT), lactic acid (ABL), c-reactive protein (CRP) and interleukin 2 (IL 2) and interleukin 8 (IL - 8) level changes and the occurrence of adverse reactions.Results: The respiratory recovery time, eye-opening time, extubation time and restlessness score of the observation group were significantly lower than those of the control group (P<0.05); before operation, there was no significant difference in the level of liver and kidney function between the two groups; after operation, the liver and kidney function of the two groups were increased, but there was no significant difference in the level of BUN and Cr between the two groups; ALT, AST and TBIL of the observation group were significantly lower than those of the control group (P<0.05) Before operation, there was no significant difference in the level of oxygenation index between the two groups; after operation, the level of oxygenation index in the two groups increased, and the QS / QT and ABL levels in the observation group were significantly lower than those in the control group (P<0.05); before operation, there was no significant difference in the level of stress reaction between the two groups; after operation, the level of stress reaction in the two groups increased on average, and the level of CRP, IL-2 and IL-8 in the observation group were significantly lower than those in the control group (P<0.05).The total incidence of adverse reactions in the two groups was 5.66% and 19.15%, respectively, with significant difference (P<0.05).Conclusion: Epidural block combined with general anesthesia in patients with radical gastrectomy has a significant effect, and can effectively improve the liver function and oxygenation function level of patients, which is worthy of promotion and application.
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2020, Vol. 26 
