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| Effects of Different Plate Internal Fixation Techniques on Serum SP, NPY Levels and Knee Joint Function in Patients with Tibial Plateau Fractures |
| ZHANG Penggui, LIU Liedong, DONG Jianbin, et al |
| Yulin First Hospital, Shaanxi Yulin 719000, China |
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Abstract Objective: To investigate the effects of different plate internal fixation techniques on serum substance P (SP), neuropeptide (NPY) levels and knee joint function in patients with tibial plateau fractures.Methods: From January 2017 to September 2018, 74 patients with tibial plateau fractures in our hospital were prospectively studied and randomly categorized into two groups with random number table method, 37 cases in each.Group A underwent minimally invasive internal fixation system (LISS) plate technology, and group B underwent anatomical plate internal fixation.The operative indexes, complication rate, perioperative pain stress (serum SP, NPY), varus angle, caster angle, knee joint range of motion and distinguished achiever ratio of knee joint function recovery at three months, six months and twelve months after the operation were compared.Results: The operation time, intraoperative blood loss, and postoperative drainage volume of group A were lower than those of group B, and the length of the incision was shorter than that of group B (P<0.05); serum SP and NPY levels in group A were lower than those in group B at the first, third, and seventh days after surgery (P<0.05); there was no significant difference between the two groups after three, six, and twelve months of varus angle, caster angle, knee joint range of motion (P>0.05); the excellent recovery rate of knee function in group A (81.08%) was not significantly different from that in group B (78.38%) (P>0.05); there was no significant difference in the incidence of complications between group A and group B (P>0.05).Conclusion: The anatomical plate internal fixation technology and LISS plate internal fixation technology have high safety and good knee joint function recovery.However, compared with the anatomical plate internal fixation technique, the LISS plate internal fixation technique has a shorter incision, which can obviously reduce the amount of intraoperative bleeding in patients with tibial plateau fractures, reduce the postoperative pain stress response, and accelerate the postoperative rehabilitation process, with high clinical promotion value.
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2020, Vol. 26 
