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| An Analysis of Diagnostic Value on Etiological Classification of PCT and CRP/Alb Ratio in Serum of Patients Suffering from SAP |
| XU Mojun, SUN Xiangjun |
| Langfang People's Hospital, Hebei Langfang 065000, China |
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Abstract Objective: To analyze diagnostic value on etiological classification for stroke associated pneumonia (SAP), by detection on the PCT and CRP/Alb ratio in serum of patients suffering from stroke. Methods 368 patients suffering from SAP hospitalized from January 2017 to November 2019 were selected, and then, based on the results of sputum culture, were divided into the positive group(n=211) and the negative group(n=157). The patients who were hospitalized with stroke but without infection were made the control group(n=157). The clinical data of each group were analyzed retrospectively, and the PCT and CRP/Alb ratio in serum , the results of sputum culture and the serological examination of the pathogen as well. Results:Compared with the control group, the PCT and CRP/Alb ratio in serum of the patients in the observation group were significantly elevated(0.73±0.22vs0.07±0.03; 0.87±0.23vs0.48±0.19 P<0.05). Among the 368 patients suffering from SAP, 211(57.3%)sputum cultures were positive. Gram-positive bacteria were 79(37.3%), Gram-negative bacteria, 91(43.0%), fungus, 17(8.2%) , the rest of sputum cultures, 24(11.4%), mainly including Escherichia coli, Klebsiella Pneumoniae, acinetobacter Bowman, Staphylococcus Aureus, Streptococcus Pneumoniae, Candida Albicans, Candida Tropicalis, Candida Glabrata, et al. The PCT and CRP/Alb ratio in serum of the patients the positive group of sputum bacteria culture were higher than the negative group(1.19±0.34vs0.62±0.27; 2.19±0.45vs1.49±0.28 P<0.05). After examining the serological identification results of the patients in the observation group, 243 cases (66.3%) had bacterial infection, 56 cases (15.2%) had viral infection, 43 cases (11.7%) had mycoplasma infection, 26 (7.1%) of the rest were found with other infections. The PCT and CRP/Alb ratio in serum of the patients of the bacterial infection group were significantly higher than the viral infection group and the mycoplasma infection group(1.26±0.28vs0.51±0.14vs 0.12±0.03;2.37±0.69vs1.79±0.56vs0.38±0.24 P<0.05). Conclusion: The most common pathogens in patients with SAP were bacteria, virus, mycoplasma and fungi. Serum CRP/Alb ratio has a certain diagnostic value on etiological classification in predicting the occurrence of SAP, It is helpful to the etiological diagnosis and it guides the clinical treatment.
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2020, Vol. 26 
