|
|
|
| The Curative Effect of Early Interventional Embolization on the Treatment of Intracranial Aneurysm and Its Effect on the Patients' Neurological Function Mental State and Activities of Daily Living |
| LI Jiangtao, YANG Hua, FAN Yujun |
| The First People's Hospital of Guangyuan, Sichuan Guangyuan 628000, China |
|
|
|
|
Abstract Objective: To explore the therapeutic effect of early interventional embolization in the treatment of intracranial aneurysms, and to observe the effects of early interventional embolization on the neurological function, mental state and activities of daily living of the patients. Methods: The patients with intracranial aneurysm (n=84) from March 2016 to March 2019 were selected as experimental subjects, and divided into two groups with the random digital table method. The control group (n=42) was treated with advanced interventional embolization, and the observation group (n=42) was treated with early intervention. The clinical effect, complication rate, prognosis, neurological function score (NIHSS), daily life ability score (ADL) and mental state score (KPS) were observed before and after treatment. Results: The total effective rate of the observation group was 95.24% in comparison with 71.43% of the total effective rate of the control group(χ2=8.571, P<0.05).Compared with 14.29% of the mortality rate and 23.81% of the disability rate in the control group, the mortality rate in the observation group was 2.38% and the disability rate was 4.76% The difference between the two groups was obvious and statistically significant(P<0.05). The results of repeated ANOVA showed that the NHISS score, KPS score, ADL score, intra-subject effect and inter-subject effect of different time points were statistically significant(P<0.05).The NHISS score of the patients in the observation group was (14.50±1.81), which was significantly lower than that in the control group [(20.19±4.24), P<0.05].The scores of KPS (86.05±6.84) were higher than that in the control group[(78.36±7.58), P<0.05]. The score of ADL (78.45±7.62) was significantly higher than that in the control group[(61.57±8.06), P<0.05], and the MMSE score (26.52±4.17) was significantly higher than that in the control group[(19.86±4.71), P<0.05].Compared with 26.19% of the total complications in the control group, the total incidence of complications in the observation group was 7.14%. There was significant difference between the two groups(χ2=5.486, P<0.05). Conclusion: Compared with advanced interventional embolism, early interventional embolism has a better effect on intracranial aneurysm, which can significantly improve the neurological status of patients, improve the ability of daily living, restore neurological function, effectively reduce complications, and the prognosis of patients is good.
|
|
|
|
|
|
[1] 何婉玲, 袁惠萍, 罗鹏.针对性护理在颅内动脉瘤围手术期的临床效果[J].实用医学杂志, 2017, 33(24):4180~4182.
[2] Xianli Lv, Huijian Ge, Hongwei He, 等. A systematic review of pipeline embolization device for giant intracranial aneurysms[J]. Neurology India, 2017, 65(1):35~38.
[3] 李丽, 温霞.前列地尔联合依达拉奉对急性脑梗死合并高血压患者凝血功能血浆cTnIHcyPCT水平及神经功能的影响[J].河北医学, 2019, 25(5):787~791
[4] Robert lusarz, Monika Biercewicz, Barbara Smarszcz, et al. Application of the functional capacity scale in the early assessment of functional efficiency in patients after aneurysm embolization: Preliminary reports[J]. Advances in Clinical and Experimental Medicine, 2017, 26(6):981~986.
[5] 廖可立, 童瑜, 陈贵军, 等.吲哚菁绿荧光血管造影在颅内动脉瘤手术中的应用[J].新乡医学院学报, 2019, 36(3):234~237.
[6] De-zhang Huang, Bin Jiang, Wei He, et al. Risk factors for the recurrence of an intracranial saccular aneurysm following endovascular treatment[J]. Oncotarget, 2017, 8(20):33676~33682.
[7] 郑津, 胡学斌, 赵洪洋, 等.血管介入栓塞治疗时机对颅内动脉瘤患者并发症及神经功能的影响[J].中国医药, 2018, 13(2):219~223.
[8] Christoph Kabbasch, Lukas Goertz, Eberhard Siebert, . WEB embolization versus stent-assisted coiling: comparison of complication rates and angiographic outcomes[J]. Journal of Neurointerventional Surgery, 2019, 11(8):812~816.
[9] Jun Kyeung Ko, Won Ho Cho, Seung Heon Cha, et al. Semi-jailing technique using a neuroform3 stent for coiling of wide-necked intracranial aneurysms[J]. Journal of Korean Neurosurgical Society, 2017, 60(2):146~154.
[10] 沈育.颅内动脉瘤显微夹闭手术124例疗效分析及影响预后的危险因素[J].安徽医药, 2018, 22(6):1087~1090. |
|
|
|
2020, Vol. 26 
