瑞芬太尼或芬太尼复合丙泊酚全麻对老年手术患者心功能及血流动力学指标的影响对比

doi:10.3969/j.issn.1006-6233.2020.07.034

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Abstract Objective: To investigate the effects of remifentanil or fentanyl combined with propofol general anesthesia on cardiac function and hemodynamic parameters in elderly patients. Methods: A total of 220 elderly patients admitted to our hospital from December 2017 to June 2019 were randomly divided into observation group (110 cases) and control group (110 cases). The changes of heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (map), left ventricular ejection fraction (LVEF), cardiac stroke volume (SV), cardiac output (CO), cardiac index (CI) were compared before anesthesia induction (t0), before tracheal intubation (T1), immediately after tracheal intubation (T2), at the time of skin incision (T3) and 10 minutes after operation (T4) The operation related indexes and complications of the two groups were recorded. Results: There was no significant difference in HR, SBP, DBP, map, LVEF%, SV, CO and CI between the two groups in t0 and T4 period (P > 0.05). The time of extubation, time of opening eyes, time of spontaneous respiration, time of recovery of orientation force and incidence of adverse reactions in the observation group were significantly lower than those in the control group (P < 0.05). Conclusion: Remifentanil combined with propofol for general anesthesia can stabilize the patient's heart function and hemodynamics, improve the awake time and safety of patients, and it is worthy of popularization.

Key words： Remifentanil Propofol Cardiac function Hemodynamics

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	CHEN Yuanli
	XIE Jian
	CHEN Fei

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CHEN Yuanli,XIE Jian,CHEN Fei. Comparison on Effects of Remifentanil or Fentanyl Combined with Propofol General Anesthesia on Cardiac Function and Hemodynamic Parameters in Elderly Patients Undergoing Surgery[J]. HeBei Med, 2020, 26(7): 1200-1204.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2020.07.034 OR http://www.hbyxzzs.cn/EN/Y2020/V26/I7/1200

[1] 尹秀荣.丙泊酚联合瑞芬太尼靶控输注麻醉在老年腹腔镜手术中的应用价值[J].现代中西医结合杂志,2015,24(5):541~543.
[2] 高芳,张月英.瑞芬太尼与异氟醚对老年患者全麻术后认知功能影响的比较[J].徐州医学院学报,2015,4(4):47~49.
[3] Xue ZJ. Efficacy of entropy index in monitoring nociceptive stimulus in patients undergoing propofol-remifentanil general anesthesia [J]. Medicinae Sinicae, 2014, 36(1): 68~72.
[4] 肖春龙.丙泊酚复合瑞芬太尼全凭静脉麻醉对老年开胸术后认知功能和疼痛的影响[J].现代中西医结合杂志,2016,25(32):3631~3633.
[5] Choi J W, Joo J D, Kim D W, et al. Comparison of an intraoperative infusion of dexmedetomidine, fentanyl and remifentanil on perioperative hemodynamics, sedation quality and postoperative pain control [J].Korean Med Sci, 2016, 31(9) : 1485~1490.
[6] Akai N, Kawasaki Y, Waragai T, et al. Successful therapy with tonsillectomy plus pulse therapy for the relapse of pediatric IgA nephropathy treated with multidrugs combination therapy[J]. Fukushima Med Sci, 2016, 62 (1): 68~73.
[7] Yenigun A, Et T, Aytac S, et al. Comparison of different administration of ketamine and intravenous tramadol hydrochloride for postoperative pain relief and sedation after pediatric tonsillectomy [J].Craniofac Surg, 2015, 26(1): 21~24.
[8] Sato M, Kurosawa A, Sasakawa T, et al. Evaluation of the effects of remifentanil doses on hemodynamics and perfusion index at the onset of pneumoperitoneum during laparoscopic surgery [J]. Masui, 2016, 65(6): 573~577.
[9] Gupta A, Stierer T, Zuckerman, et al. Comparison of recovery profile after ambulatory anesthesia with propofol isoflurane sevoflurane and desfluranera systematic review [J]. Anesth Analg, 2015, 98 (3) : 632~641.
[10] Gan TJ, Meyer TA, Apfel CC, et al. Society for ambulatory anesthesia guidelines for the management of postoperative nausea and vomiting[J]. Ambulatory Anesthesiology, 2015, 105 (6) : 1615~1628.
[11] Jung SY. The effect of a subhypnotic with sevoflurane and remifentanil [J]. Korean Journal of Anesthesiology, 2014,66(2):120~126.
[12] 柴林,刘智慧,郑智文,等.靶控输注依托咪酯联合瑞芬太尼对老年手术患者机体免疫及应激反应指标的影响[J].中国药房,2017,28(15):2036~2039.
[13] 李佳玉,金立民,吴津,等.部分神经肌肉阻滞下七氟烷或丙泊酚复合瑞芬太尼应用于老年脑干肿瘤手术对诱发电位监测的影响[J].中国老年学杂志,2016,36(13):3234~3237.
[14] 刘丽,彭明清,王中林,等.瑞芬太尼复合丙泊酚对老年子宫切除手术患者免疫功能、血流动力学及应激反应的影响[J].中国老年学杂志,2017,37(3):670~672.
[15] Xue Z J.Efficacy of entropy index in monitoring nociceptive stimulus in patients undergoing propofol-remifentanil general anesthesia [J]. Medicinae Sinicae, 2014, 36(1): 68~72.
[16] 王叔衡,赵静,李胜锦,等.七氟醚复合瑞芬太尼对扁桃体切除术患儿苏醒期躁动及术后镇痛的影响[J].现代生物医学进展,2017,17(16):3136~3139.
[17] Nishiyama Y. The hemodynamics and bispectral index score during lower abdominal surgery under balanced anesthesia with the two different combination doses of desflurane and remifentanil [J]. Masui, 2015, 64(6): 615~618.
[18] Yenigun A,Et T,Aytac S,et al. Comparison of different administration of ketamine and intravenous tramadol hydrochloride for postoperative pain relief and sedation after pediatric tonsillectomy [J].Craniofac Surg, 2015, 26(1): 21~24.
[19] Sakai W, Yoshikawa Y, Hirata N, et al. Effect of remifentanil during cardiopulmonary bypass on incidence of acute kidney injury after cardiac surgery [J].Anesth, 2017, 31(6): 895~902.
[20] Park JS, Kim KJ, Lee JH, et al. A randomized comparison of remifentanil target-controlled infusion versus dexmedetomidine single-dose administration[J]. AmericanJournalof Therapeutics, 2016, 23(3): e690~e696.