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| Correlation Analysis Between Levels of Four Serum Lipid Indexes Serum Homocysteine and Occurrence of Acute Cerebral Infarction in Patients with H-type Hypertension |
| WANG Junjun, WANG benxiao, TANG Yongliang, et al |
| Wanbei Coal Power Group General Hospital / the Third Affiliated Hospital of Bengbu Medical College, Anhui Suzhou 234011, China |
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Abstract Objective: To analyze the correlation between levels of four serum lipid indexes, serum homocysteine (Hcy) and occurrence of acute cerebral infarction (ACI) in patients with H-type hypertension. Methods: Eighty patients with H-type hypertension who were admitted to the hospital from August 2018 to July 2019 were enrolled as study objects. According to presence or absence of ACI, they were divided into ACI group (n=30) and non-ACI group (n=50). Another 40 healthy people after physical examination in the hospital during the same period were enrolled as control group. The general data, levels of four serum lipid indexes [triglyceride (TG), cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C)] and serum Hcy were compared among the three groups. The correlation between levels of four serum lipid indexes, serum Hcy and occurrence of ACI in patients with H-type hypertension was analyzed. Results: The systolic blood pressure in ACI group and non-ACI group was higher than that in control group (P<0.05). Serum TC, TG, LDL-C and Hcy levels in ACI group were higher than those in non-ACI group (P<0.05), while serum HDL-C levels were lower than non-ACI group (P<0.05). Serum TC, TG, LDL-C and Hcy levels were positively correlated with the occurrence of ACI (P<0.05), while serum HDL-C level was negatively correlated with it (P<0.05). Serum TC, TG, HDL-C, LDL-C and Hcy were influencing factors of ACI in patients with H-type hypertension (P<0.05). Conclusion: There is correlation between levels of four serum lipid indexes, serum Hcy and occurrence of ACI in patients with H-type hypertension. Clinical monitoring on levels of four serum lipid indexes and serum Hcy is of important value for assessing occurrence of ACI in patients with H-type hypertension.
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2020, Vol. 26 
