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| Clinical Observation of Laparoscopic Cholecystectomy and Mini-incision Cholecystectomy for Cholelithiasis and its Effect on Immune Function |
| FANG Jian, KAI Zhe, CHEN Zhuming |
| Anqing First People's Hospital / Anqing Hospital, Guangdong Medical University, Anhui Anqing 246000, China |
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Abstract Objective: To explore the clinical observation of laparoscopic cholecystectomy and mini-incision cholecystectomy for cholelithiasis and its effect on immune function. Methods: 104 patients with cholecystolithiasis undergoing elective surgery in general surgery of our hospital between October 2017 and April 2019 were divided into the test group(n=52) and the control group(n=52) by simple random grouping method. Patients in the control group were treated with mini-incision cholecystectomy, while patients in the test group were treated with laparoscopic cholecystectomy. The operation conditions, postoperative complications and T lymphocyte subsets between the two groups were compared. Results: The total effective rate of the test group was significantly higher than that of the control group (94.2% vs 76.9%, P<0.05). The incidence of postoperative complications in the test group was lower than that in the control group (11.5% vs. 26.9%, P<0.05). The total incision length, operation time, postoperative hospitalization time, anal exhaust time and ambulation time of the taet group were shorter than those of the control group, and the intraoperative blood loss was less than that of the control group (P<0.05). The levels of CD3+T, CD4+T, CD4+T/CD8+T in the test group were higher than those in the control group (P<0.05). Conclusion: Laparoscopic cholecystectomy with smaller incision cholecystectomy has better therapeutic effect on patients with gallstone, less immunosuppression and better postoperative recovery.
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2020, Vol. 26 
