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| The Significance of Combined Indocyanine Green and Isosulfan Blue Tracing Sentinel Lymph Nodes in Open Surgery of Uterine Malignant Carcinoma |
| ZHUANG Xinrong, LI Shumei, ZHANG Guixiang |
| The Affiliated Hospital of Chengde Medical College, Hebei Chengde 067000, China |
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Abstract Objective: To evaluate the value of indocyanine green(ICG) and isosulfan blue(ISB) for identifying sentinel lymph node (SLN) in uterine malignant carcinoma. Methods: 60 patients (34 cases of endometrial cancer and 26 cases of cervical cancer) who underwent open surgery in affiliated hospital of chengde medical college were selected. ISB and ICG were injected into the cervix of cervical cancer and around the lesion in the patients with endometrial cancer. All the SLN and other lymph nodes were labeled postoperatively and sent for routine pathological examination. Results: The total detection rate of pelvic SLN was 91.7% (55 / 60) using ICG combined with ISB, the sensitivity and negative predictive value were all 100%. The detection rate of ICG and ISB was 81.7% (49/60) and 71.7% (43/60), respectively. Detection rate of SLN with combined technique was higher than that with single technique, ICG detection rate was higher than ISB technique (P<0.05). Conclusion: ICG combined with ISB tracing SLN showed high sensitivity and negative predictive value. Combined detection method is superior to single technique and will have a certain application prospect in prediction of lymph node metastasis in open surgery of uterine malignant carcinoma.
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2020, Vol. 26 
