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| Study on the Effect of Perioperative Application of Cefotaxime Sodium on Infection in Emergency Trauma Patients |
| TAN Jun, et al |
| Minda Hospital Affiliated to Hubei University for Nationalities, Hubei Enshi 445000, China |
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Abstract Objective: To investigate the effect of cefotaxime sodium on the infection of patients with trauma in perioperative period. Methods: A total of 120 trauma patients admitted to the emergency department were enrolled between January 2016 and December 2018. They were simple random grouping into two groups according to the random number table: 60 patients in the control group underwent routine clinical therapy. 60 patients in the group were treated with cefotaxime sodium anti-infective treatment based on the same clinical routine treatment as the control group. The changes of body temperature, white blood cells and CRP were measured in the two groups. The clinical efficacy and infection rate of the two treatment methods were evaluated. And wound healing rate, the data results were processed using statistical software SPSS19.0. Results: The study showed that there were no differences in white blood cell and body temperature and CRP levels between the two groups (P>0.05). On the 3rd postoperative day, the body temperature, WBC and CRP levels of the two groups were lower than those before the operation, but the experimental group was significantly lower than the control group (P<0.05). Compared with the control group, the treatment efficiency of the experimental group was significantly better (95.00% vs 76.67%) (P<0.05). After treatment, the infection rate of the experimental group was 3.33%, which was significantly lower than 16.67% of the control group (χ2=5.926, P<0.05). After treatment, the grade A healing rate was 51.67%, the grade B healing rate was 43.33%, and the grade C healing rate was 5.00%. The grade A healing rate was 31.67%, and the grade B healing rate was 38.33%. The rate was 30.00%; the two groups were compared (U=2.395, P=0.031). Conclusion: In the treatment of infection in perioperative emergency trauma patients, cefotaxime sodium has significant effect and high safety.
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2020, Vol. 26 
