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| Effect of Laparoscopic Left Hepatic Pedicle Occlusion in the Treatment of Intrahepatic Bile Duct Stones and the Influence on Liver Function and Stress Index after Operation |
| WUjisiguleng, ZHANG Tong, WANG Wanxiang |
| Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Hohhot 010059, China |
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Abstract Objective: To study the effect of laparoscopic left hepatic pedicle occlusion in the treatment of intrahepatic bile duct stones and its influence on liver function and stress index after operation. Methods: 102 intrahepatic bile duct stones who received therapy from February 2017 to February 2018 in our hospital were selected as research objects. According to random number table,those patients were divided into the observation group (n=52) and the control group (n=50). The control group was treated with laparotomy, while the observation group treated with Laparoscopic left hepatic pedicle occlusion. Then the Surgical indicators (operation time, intraoperative blood loss, time of hepatic portal exhaust, time of getting out of bed, time of hospitalization), liver function indicators of Aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (TBIL), stress indicators (adrenaline, cortisol), incidence of adverse reactions of two groups after treatment were compared. Results: After treatment, The operation time, intraoperative blood loss, portal exhaust time, ambulation time and hospitalization time in the observation group were significantly lower than those in the control group[(204.85±31.87)min vs(273.75±36.52)min,(182.47±40.32)ml vs(227.38±51.28)ml,(21.08±6.37)h vs(46.24±11.76)h,(1.94±0.42)d vs(3.02±0.61)d,(12.05±2.53)d vs(17.32±3.97)d](P＜0.05). AST, ALT and TBIL were significantly lower than those in the control group[(87.47±20.86)U/L vs(101.38±23.97)U/L,(71.97±16.42)U/L vs(90.43±17.94)U/L,(46.83±12.31)μmol/L vs(60.25±14.92)μmol/L](P＜0.05). The levels of adrenaline and cortisol in each node were significantly lower than those in the control group(P＜0.05). The total incidence of adverse reactions was significantly lower than that in the control group [5.76%(3/52)vs28.00％(14/50)](P＜0.05). Conclusion: Laparoscopic left hepatic pedicle occlusion is effective in the treatment of intrahepatic bile duct stones. It can recover quickly after operation. It can reduce the stress reaction to the body and promote the recovery of liver function. It has fewer complications and is safe and reliable.
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2019, Vol. 25 
